Autism Single Investigator Innovation Program (Autism-SIIP) – Autism Transitions Research Project (ATRP)

Autism Single Investigator Innovation Program (Autism-SIIP) – Autism Transitions Research Project (ATRP) is sponsored by Health Resources and Services Administration (HRSA). This program supports primary and secondary research studies that advance the evidence base on the social determinants and risk factors associated with healthy life outcomes among adolescents and young adults with Autism Spectrum Disorder (ASD) who are transitioning to adulthood.

Autism Single Investigator Innovation Program (Autism-SIIP) – Autism Transitions Research Project (ATRP) | HRSA 22 099 Autism Single Investigator Innovation Program (Autism-SIIP) – Autism Transitions Research Project (ATRP) | HRSA 22 099 Department of Health and Human Services, Health Resources and Services Administration Opportunity Information: Apply for HRSA 22 099 The Autism Single Investigator Innovation Program (Autism-SIIP) Autism Transitions Research Project (ATRP) is a federal grant opportunity from the U.S. Department of Health and Human Services, Health Resources and Services Administration (HRSA).

It is offered as a discretionary cooperative agreement (Funding Opportunity Number HRSA-22-099; CFDA 93. 877) focused on strengthening the research evidence around what helps adolescents and young adults with autism spectrum disorder (ASD) achieve healthier, more stable outcomes as they transition into adulthood.

The program is specifically interested in how social determinants of health and other risk or protective factors shape life outcomes across multiple domains, including physical health, mental and emotional or behavioral health, social functioning, and educational or occupational success.

At its core, ATRP is designed to fund both primary and secondary research that can clarify what drives better adult-transition outcomes for youth with ASD and what gets in the way. A key expectation is that applicants will not only analyze existing data or conduct observational studies, but also carry out at least one pilot intervention study.

The pilot requirement signals that HRSA wants projects to move beyond describing problems and toward testing practical, innovative approaches that could later be expanded.

Applicants are also encouraged to use ATRP-supported work as a springboard to compete for additional external funding to run full-scale intervention studies in the future, meaning the award is meant to catalyze a longer research and implementation pipeline rather than stand alone as a one-time study. HRSA lays out several priority areas to help applicants align their research with real-world transition needs.

Examples include addressing co-occurring mental health conditions that are common in transition-age youth with ASD, strengthening training for both pediatric and adult health care providers on effective health care transition practices for autistic patients, and improving pathways tied to employment, career development, and long-term economic well-being.

Transportation is also highlighted, reflecting how access to reliable transportation can directly affect health care access, education, employment, and social participation for young adults with ASD. While these examples are not the only acceptable topics, they indicate the program is looking for research questions that are tightly connected to day-to-day adult functioning and systems of care.

Another major purpose of ATRP is to shape the next generation of autism transition research by pinpointing gaps in what is currently known. This includes gaps in understanding life outcomes, service needs, and service access during the transition period, as well as gaps in identifying which service delivery or program models actually work.

HRSA is looking for projects that can clarify what supports are missing, what barriers are structural versus individual, and what kinds of interventions or service configurations might plausibly produce better outcomes at scale. Related to this, ATRP emphasizes improving how the field defines and measures "desired healthy life outcomes" for transitioning youth with ASD.

Applicants are encouraged to develop or refine measurement tools and to generate evidence demonstrating whether innovative service models are effective, helping move the field toward clearer benchmarks and more comparable results across studies. Equity is a central theme of the opportunity.

HRSA explicitly calls for innovative, empirically sound strategies aimed at increasing equity in healthy life outcomes, with an emphasis on underserved communities. In practice, this points to research that does not treat disparities as an afterthought, but instead designs studies and interventions that directly address uneven access to diagnosis, care, transition planning, employment supports, or community resources.

It also encourages applicants to examine how factors such as geography, income, race and ethnicity, language, disability complexity, and service availability shape transition experiences and outcomes for autistic youth and young adults. The opportunity also prioritizes identifying barriers that delay or prevent timely access to services during the transition to adulthood.

That can include barriers in eligibility rules, insurance coverage changes, handoffs between pediatric and adult systems, workforce shortages, fragmented service delivery, limited provider training, transportation limitations, and administrative burdens that families and young adults face.

By mapping these barriers clearly and tying them to measurable outcomes, HRSA is aiming to support work that can inform policy, program design, and health system practices. Finally, ATRP places value on dissemination and public impact.

Beyond producing research findings, awardees are expected to help raise national and public awareness of the factors associated with better outcomes for transitioning adolescents and young adults with ASD.

This includes providing leadership in communicating results from ATRP-supported research, which typically means translating evidence for stakeholders such as clinicians, educators, workforce programs, community service providers, policymakers, autistic individuals, and families.

The overall intent is to ensure the work meaningfully influences practice and future research directions rather than remaining confined to academic publication channels. In terms of logistics, this opportunity was created on January 4, 2022, with an original closing date of April 4, 2022. HRSA anticipated making one award, with an award ceiling of $500,000.

Eligible applicants were broad and included various levels of government (state, county, city/township, and special districts), public and private institutions of higher education, federally recognized tribal governments and other tribal organizations, and nonprofits with 501(c)(3) status, among others as allowed in the full eligibility guidance.

This wide eligibility is consistent with HRSA's interest in supporting research that is both scientifically rigorous and grounded in the systems that serve transition-age youth with ASD.

The Department of Health and Human Services, Health Resources and Services Administration in the health sector is offering a public funding opportunity titled " Autism Single Investigator Innovation Program (Autism-SIIP) – Autism Transitions Research Project (ATRP) " and is now available to receive applicants. Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93. 877 .

This funding opportunity was created on Jan 04, 2022. Applicants must submit their applications by Apr 04, 2022. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)

Each selected applicant is eligible to receive up to $500,000. 00 in funding. The number of recipients for this funding is limited to 1 candidate(s).

Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others (see text field entitled Additional Information on Eligibility for clarification).

[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal: Your browser does not support the video tag. Autism Transitions Research Project (ATRP) - FAQs What is the Autism Transitions Research Project (ATRP)?

ATRP is a federal grant opportunity under the Autism Single Investigator Innovation Program (Autism-SIIP) from the U.S. Department of Health and Human Services (HHS), Health Resources and Services Administration (HRSA). It supports research to strengthen evidence about what helps adolescents and young adults with autism spectrum disorder (ASD) achieve healthier, more stable outcomes as they transition into adulthood.

Which federal agency is offering this opportunity? The opportunity is offered by HRSA (Health Resources and Services Administration), within HHS (U.S. Department of Health and Human Services). Is this a grant or a cooperative agreement?

This opportunity is offered as a discretionary cooperative agreement. What is the Funding Opportunity Number and CFDA listing? Funding Opportunity Number (FON): HRSA-22-099.

CFDA: 93. 877. What is the main goal of ATRP?

The main goal is to build the research evidence base on factors that influence adult-transition outcomes for youth and young adults with ASD, including what improves outcomes and what creates barriers during the transition to adulthood. Who is the population of interest for this program? The program focuses on adolescents and young adults with autism spectrum disorder (ASD), specifically during the transition into adulthood.

What kinds of outcomes does ATRP care about? ATRP highlights outcomes across multiple domains, including physical health, mental and emotional or behavioral health, social functioning, and educational or occupational success. How do social determinants of health fit into the research focus?

The program is explicitly interested in how social determinants of health, along with other risk and protective factors, shape life outcomes during the transition to adulthood for youth with ASD. What types of research does ATRP fund? ATRP is designed to support both primary and secondary research.

This includes analyzing existing data, conducting observational studies, and testing practical approaches through intervention work. Is an intervention study required? Yes.

A key expectation is that funded projects will include at least one pilot intervention study, reflecting HRSA's interest in moving beyond describing problems to testing innovative approaches. Why does HRSA require a pilot intervention study? The pilot requirement is meant to encourage projects to test practical, innovative strategies that could later be expanded, rather than stopping at observational or descriptive findings.

Does HRSA expect this work to lead to additional funding later? Applicants are encouraged to use ATRP-supported work as a springboard to compete for additional external funding for future full-scale intervention studies, suggesting the award is intended to catalyze a longer research and implementation pipeline. What are examples of HRSA priority topics for ATRP?

Examples mentioned include: addressing co-occurring mental health conditions among transition-age youth with ASD; strengthening training for pediatric and adult health care providers on effective health care transition practices; improving pathways related to employment, career development, and long-term economic well-being; and transportation as a factor affecting access to health care, education, employment, and social participation.

Are applicants limited to the listed priority topics? No. The examples are described as illustrative rather than the only acceptable topics, but they indicate HRSA is looking for research tied closely to real-world adult functioning and systems of care. What does ATRP mean by identifying research gaps?

ATRP aims to pinpoint gaps in knowledge about life outcomes, service needs, and service access during the transition period, as well as gaps in understanding which service delivery or program models actually work. What kinds of barriers is ATRP interested in studying? The program prioritizes identifying barriers that delay or prevent timely access to services during the transition to adulthood.

Examples include eligibility rules, insurance coverage changes, handoffs between pediatric and adult systems, workforce shortages, fragmented service delivery, limited provider training, transportation limitations, and administrative burdens for families and young adults. How does ATRP approach the measurement of outcomes?

ATRP emphasizes improving how the field defines and measures "desired healthy life outcomes" for transitioning youth with ASD. Applicants are encouraged to develop or refine measurement tools and generate evidence that helps establish clearer benchmarks and more comparable results across studies. What is the role of equity in this funding opportunity?

Equity is described as a central theme. HRSA calls for innovative, empirically sound strategies aimed at increasing equity in healthy life outcomes, with an emphasis on underserved communities. What does ATRP suggest researchers examine when focusing on equity?

The opportunity encourages examination of how factors such as geography, income, race and ethnicity, language, disability complexity, and service availability shape transition experiences and outcomes for autistic youth and young adults. What is HRSA expecting in terms of dissemination and public impact?

Beyond research findings, awardees are expected to help raise national and public awareness about factors associated with better outcomes for transitioning adolescents and young adults with ASD, including leadership in communicating results to stakeholders. Who are the intended audiences for disseminating ATRP findings?

Stakeholders mentioned include clinicians, educators, workforce programs, community service providers, policymakers, autistic individuals, and families. When was this opportunity created and when did it close? The opportunity was created on January 4, 2022, and had an original closing date of April 4, 2022.

How many awards did HRSA anticipate making? HRSA anticipated making one award. What was the award ceiling?

The award ceiling was $500,000. Who was eligible to apply? Eligibility was broad and included various levels of government (state, county, city/township, special districts), public and private institutions of higher education, federally recognized tribal governments and other tribal organizations, and nonprofits with 501(c)(3) status, among others as permitted by the full eligibility guidance.

Why is eligibility so broad for this opportunity? The stated rationale is consistent with HRSA's interest in supporting research that is scientifically rigorous while also being grounded in the real-world systems that serve transition-age youth with ASD.

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