BBSRC Standard Research Grant: 2025 round 1: Responsive mode

BBSRC Standard Research Grant: 2025 round 1: Responsive mode is sponsored by Biotechnology and Biological Sciences Research Council (BBSRC). This scheme supports excellent investigator-led research across the breadth of BBSRC's scientific remit. While not exclusively for pandemic preparedness, research into infectious diseases, host-pathogen interactions, and related biological sciences can be funded.

BBSRC Standard Research Grant: 2025 round 1: Responsive mode – UKRI Funding opportunity: BBSRC Standard Research Grant: 2025 round 1: Responsive mode Biotechnology and Biological Sciences Research Council (BBSRC) 26 September 2024 9:00am UK time 15 January 2025 4:00pm UK time Last updated: 31 January 2025 - see all updates Standard research grants are available for researchers at eligible research organisations.

This scheme supports excellent investigator-led research across the breadth of Biotechnology and Biological Sciences Research Council (BBSRC) scientific remit. You must be based at a UK research organisation eligible for BBSRC funding. The full economic cost (FEC) of your project can be up to £2 million.

Funding is available for up to five years. BBSRC will fund 80% of the FEC. Before applying for funding, check the eligibility of your organisation .

For full details, visit Eligibility as an individual . See also our guidance for applicants . We will not accept uninvited resubmissions of projects that have been submitted to UKRI or any other funder.

Find out more about BBSRC’ resubmissions policy . Equality, diversity and inclusion We are committed to achieving equality of opportunity for all funding applicants. We encourage applications from a diverse range of researchers.

We support people to work in a way that suits their personal circumstances. This includes: support for people with caring responsibilities alternative working patterns Find out more about equality, diversity and inclusion at UKRI . This scheme supports excellent investigator-led research across the breadth of BBSRC scientific remit .

You are encouraged to consider the relevance of your proposed work in line with the long-term research and innovation priorities set out in BBSRC’s strategic delivery plan 2022 to 2025 . A small number of Responsive Mode Spotlight areas may be in operation at any one time, in line with the more targeted nature of the new mechanism.

The aim of the Responsive Mode Spotlight mechanism is to provide simpler, more agile, and dynamic targeting of particular areas of timely strategic interest, opportunity or need. Funding is available for: research projects, including data intensive and technology development projects.

equipment or use of existing facilities community resources, new facilities, or infrastructure research networks and coordination You can apply to undertake biotechnology or biological research in: tools and technology underpinning biological research Investigations within and across scales are supported, from molecules and cells, to tissues, whole organisms, populations and landscapes.

We welcome multidisciplinary proposals that cross into other research council areas but expect the primary focus of your work to fall within BBSRC’s remit. We work with other research councils to ensure that applications close to remit boundaries are assessed by the most appropriate lead council. Please contact remit@bbsrc.

ukri. org with any queries about the suitability of your application before applying. We have a strong commitment to funding curiosity-led research and advancing excellent bioscience across our portfolio.

The duration of this award is up to five years. The full economic cost (FEC) of your project can be up to a maximum of £2 million. We will fund 80% of the FEC.

For example, if the FEC cost of your project is equal to £2 million, we will fund £1. 6 million and your research organisation will be expected to fund £400,000). Supporting skills and talent We encourage you to follow the principles of the Concordat to Support the Career Development of Researchers and the Technician Commitment .

Trusted Research and Innovation (TR&I) UKRI is committed in ensuring that effective international collaboration in research and innovation takes place with integrity and within strong ethical frameworks.

Trusted Research and Innovation (TR&I) is a UKRI work programme designed to help protect all those working in our thriving and collaborative international sector by enabling partnerships to be as open as possible, and as secure as necessary. Our TR&I Principles set out UKRI’s expectations of organisations funded by UKRI in relation to due diligence for international collaboration.

As such, applicants for UKRI funding may be asked to demonstrate how their proposed projects will comply with our approach and expectation towards TR&I, identifying potential risks and the relevant controls you will put in place to help proportionately reduce these risks. See further guidance and information about TR&I , including where you can find additional support.

We are running this funding opportunity on the new UK Research and Innovation (UKRI) Funding Service so please ensure that your organisation is registered. You cannot apply on the Joint Electronic Submissions (Je-S) system. The project lead is responsible for completing the application process on the Funding Service, but we expect all team members and project partners to contribute to the application.

Only the lead research organisation can submit an application to UKRI. Select ‘Start application’ near the beginning of this Funding finder page. Confirm you are the project lead.

Please allow at least 10 working days for your organisation to be added to the Funding Service. We strongly suggest that if you are asking UKRI to add your organisation to the Funding Service to enable you to apply to this Opportunity, you also create an organisation Administration Account. This will be needed to allow the acceptance and management of any grant that might be offered to you.

Answer questions directly in the text boxes. You can save your answers and come back to complete them or work offline and return to copy and paste your answers. If we need you to upload a document, follow the upload instructions in the Funding Service.

All questions and assessment criteria are listed in the How to apply section on this Funding finder page. Allow enough time to check your application in ‘read-only’ view before sending to your research office. Send the completed application to your research office for checking.

They will return it to you if it needs editing. Your research office will submit the completed and checked application to UKRI. Where indicated, you can also demonstrate elements of your responses in visual form if relevant.

You should: use images sparingly and only to convey important information that cannot easily be put into words insert each new image onto a new line provide a descriptive legend for each image immediately underneath it (this counts towards your word limit) ensure files are smaller than 5MB and in JPEG, JPG, JPE, JFI, JIF, JFIF, PNG, GIF, BMP or WEBP format Watch our research office webinars about the new Funding Service .

For more guidance on the Funding Service, see: how applicants use the Funding Service how research offices use the Funding Service how reviewers use the Funding Service Applications should be self-contained, and hyperlinks should only be used to provide links directly to reference information. To ensure the information’s integrity is maintained, where possible, persistent identifiers such as digital object identifiers should be used.

Assessors are not required to access links to carry out assessment or recommend a funding decision. You should use your discretion when including references and prioritise those most pertinent to the application. References should be included in the appropriate question section of the application and be easily identifiable by the assessors for example (Smith, Research Paper, 2019).

You must not include links to web resources to extend your application. BBSRC must receive your application by 15th January 2025 at 4:00pm UK time. You will not be able to apply after this time.

Make sure you are aware of and follow any internal institutional deadlines. Following the submission of your application to the funding opportunity, your application cannot be changed, and applications will not be returned for amendment. If your application does not follow the guidance, it may be rejected.

BBSRC, as part of UKRI, will need to collect some personal information to manage your Funding Service account and the registration of your funding applications. We will handle personal data in line with UK data protection legislation and manage it securely. For more information, including how to exercise your rights, read our privacy notice .

BBSRC, as part of UKRI, will need to share the application and any personal information that it contains with DEFRA or international funders (if you are applying via an international scheme) so that they can participate in the assessment process. For more information on how DEFRA uses personal information, visit DEFRA’s website . BBSRC, as part of UKRI, will publish the outcomes of this funding opportunity at UKRI Gateway to Research .

If your application is successful, we will publish some personal information on this site. In plain English, provide a summary we can use to identify the most suitable experts to assess your application. We usually make this summary publicly available on external-facing websites, therefore do not include any confidential or sensitive information.

Make it suitable for a variety of readers, for example: the wider research community Guidance for writing a summary Clearly describe your proposed work in terms of: the challenge the project addresses potential applications and benefits its relevance to the BBSRC long-term research and innovation priorities and, if applicable Responsive Mode Spotlight areas List the key members of your team and assign them roles from the following: project co-lead (UK) (PcL) professional enabling staff research and innovation associate Only list one individual as project lead.

Find out more about UKRI’s core team roles in funding applications and our eligibility guidance . Indicate the scheme through which you are applying. In the text box, copy the number corresponding to the scheme you are applying through.

This is for administrative purposes to help the initial application processing.

Please follow the scheme specific guidance below and upload the additional documents listed as a single PDF no larger than 8MB: a letter from your institution’s technology transfer office outlining the management of outputs from the proposed research FAPESP consolidated budget form FAPESP letter of eligibility BBSRC remit classification Your application will be considered by one of our four research committees made up of independent experts.

Indicate which you feel would be best placed to assess your application. In the text box, write only the letter (in uppercase) corresponding to the committee you feel would be best placed to assess your application.

A animal disease, health and welfare B plants, microbes, food and sustainability C genes, development, and science, technology, engineering and maths (STEM) approaches to biology D molecules, cells and industrial biotechnology This is for administrative purposes to help the initial application processing. We will check your choice and make a final decision as to which committee will assess your application.

What are you hoping to achieve with your proposed work?

What the assessors are looking for in your response Explain how your proposed work: is of excellent quality and importance within or beyond the field(s) or area(s) has the potential to advance current understanding, or generate new knowledge, thinking or discovery within or beyond the field or area is timely given current trends, context, and needs impacts world-leading research, society, the economy, or the environment You may demonstrate elements of your responses in visual form if relevant.

Further details are provided in the Funding Service. References may be included within this section. How are you going to deliver your proposed work?

What the assessors are looking for in your response Explain how you have designed your approach so that it: is effective and appropriate to achieve your objectives is feasible, and comprehensively identifies any risks to delivery and how they will be managed uses a clearly written and transparent methodology (if applicable) summarises the previous work and describes how this will be built upon and progressed (if applicable) will maximise translation of outputs into outcomes and impacts describes how your, and if applicable your team’s, research environment (in terms of the place and relevance to the project) will contribute to the success of the work You may demonstrate elements of your responses in visual form if relevant.

Please make sure to check sizing and readability of the image using ‘read view’ prior to submission. Further details are provided in the service. Further details are provided in the Funding Service.

References may be included within this section.

Within the ‘Approach’ section we also expect you to: provide a detailed and comprehensive project plan including milestones and timelines in the form of an embedded Gantt chart or similar (please make sure to check sizing and readability of the image using ‘read view’ prior to submission) BBSRC’s action plan for EDI outlines our commitment to removing barriers to participation in our programmes, ensuring investments do not inadvertently prevent access or usage by individuals from minority groups, for example disabled researchers.

To this end, applications should identify how accessibility and inclusiveness in the widest sense have been incorporated into the design of the project.

For example, you may wish to reference relevant institutional strategies and policies which support equality, diversity, and inclusion as they relate to access to equipment and facilities and indicate how the proposed project has been designed and will be delivered with broad access in mind. Applicant and team capability to deliver Why are you the right individual or team to successfully deliver the proposed work?

What the assessors are looking for in your response Please ensure the current job titles of the core team members are included here to ensure eligibility can be established for the core team roles assigned. Find out more about UKRI’s core team roles in funding applications and our eligibility guidance . If relevant, please name collaborators in this section.

If applying to an international scheme, please name international collaborators in this section. Please include the research organisation for any collaborator.

Evidence of how you, and if relevant your team, have: the relevant experience (appropriate to career stage) to deliver the proposed work the right balance of skills and expertise to cover the proposed work the appropriate leadership and management skills to deliver the work and your approach to develop others contributed to developing a positive research environment and wider community You may demonstrate elements of your responses in visual form if relevant.

Further details are provided in the Funding Service. The word count for this section is 1,650 words: 1,150 words to be used for R4RI modules (including references) and, if necessary, a further 500 words for Additions.

Use the Résumé for Research and Innovation (R4RI) format to showcase the range of relevant skills you and, if relevant, your team (project and project co-leads, researchers, technicians, specialists, partners and so on) have and how this will help deliver the proposed work. You can include individuals’ specific achievements but only choose past contributions that best evidence their ability to deliver this work.

Complete this section using the R4RI module headings listed. Use each heading once and include a response for the whole team, see the UKRI guidance on R4RI .

You should consider how to balance your answer, and emphasise where appropriate the key skills each team member brings: contributions to the generation of new ideas, tools, methodologies, or knowledge the development of others and maintenance of effective working relationships contributions to the wider research and innovation community contributions to broader research or innovation users and audiences and towards wider societal benefit Provide any further details relevant to your application.

This section is optional and can be up to 500 words. You should not use it to describe additional skills, experiences, or outputs, but you can use it to describe any factors that provide context for the rest of your R4RI (for example, details of career breaks if you wish to disclose them). Complete this as a narrative.

Do not format it like a CV. References may be included within this section. For full details, see Eligibility as an individual .

Add details about any project partners’ contributions. If there are no project partners, you can indicate this on the Funding Service. A project partner is a collaborating organisation who will have an integral role in the proposed research.

This may include direct (cash) or indirect (in-kind) contributions such as expertise, staff time or use of facilities. If you are applying via the IPA/LINK scheme, please include details of industry partners here.

Add the following project partner details: the organisation name and address (searchable via a drop-down list or enter the organisation’s details manually, as applicable) the project partner contact name and email address the type of contribution (direct or in-direct) and its monetary value If a detail is entered incorrectly and you have saved the entry, remove the specific project partner record and re-add it with the correct information.

For audit purposes, UKRI requires formal collaboration agreements to be put in place if an award is made. Project partners: letters (or emails) of support Only complete a statement of support if you have named project partners in the project partner section above. A statement is required to be provided from each partner you named in the ‘Project partners’ section.

If you are applying via the IPA/LINK scheme, please include details of industry partner support here. What the assessors are looking for in your response A project partner is a collaborating organisation who will have an integral role in the proposed research. This may include direct (cash) or indirect (in-kind) contributions such as expertise, staff time or use of facilities.

confirm the partner’s commitment to the project clearly explain the value, relevance, and possible benefits of the work to them describe any additional value that they bring to the project Ensure you have prior agreement from project partners so that, if you are offered funding, they will support your project as indicated in the ‘Project partners’ section.

For audit purposes, UKRI requires formal collaboration agreements to be put in place if an award is made. Do not provide a statement of support from host and project co-leads’ research organisations. Do not provide a statement of support from collaborators.

Trusted Research and Innovation Does the proposed work involve international collaboration in a sensitive research or technology area?

What the assessors are looking for in your response Demonstrate how your proposed international collaboration relates to Trusted Research and Innovation, including: list the countries your international project co-leads, project partners and visiting researchers, or other collaborators are based in if international collaboration is involved, explain whether this project is relevant to one or more of the 17 areas of the UK National Security and Investment (NSI) Act if one or more of the 17 areas of the UK National Security and Investment (NSI) Act are involved list the areas If your proposed work does not involve international collaboration, you will be able to indicate this in the Funding Service.

If your proposed work does not involve international collaboration, please indicate this by stating ‘N/A’ We may ask you to provide additional information about how your proposed project will comply with our approach and expectation towards TR&I, identifying potential risks and the relevant controls you will put in place to help manage these risks.

Resources and cost justification What will you need to deliver your proposed work and how much will it cost? What the assessors are looking for in your response The full economic cost (FEC) of your project can be up to a maximum of £2 million. We will fund 80% of the FEC.

For example, if the FEC cost of your project is equal £2 million, we will fund £1. 6 million and your research organisation will be expected to fund £400,000 Please note, equipment over £10,000 is funded by BBSRC at 50%. The Funding Service does not currently have the ability to record this.

For this round we ask that you include equipment over £10,000 in ‘Exceptions’ at 100% of cost. We will cut this to 50% at award. You must ensure you have prior agreement from RO to fund the remaining 50%.

Justify the application’s more costly resources, in particular: significant travel for field work or collaboration (but not regular travel between collaborating organisations or to conferences) any equipment that will cost more than £10,000 any consumables beyond typical requirements, or that are required in exceptional quantities all facilities and infrastructure costs all resources that have been costed as ‘Exceptions’ Assessors are not looking for detailed costs or a line-by-line breakdown of all project resources.

Overall, they want you to demonstrate how the resources you anticipate needing for your proposed work: are comprehensive, appropriate, and justified represent the optimal use of resources to achieve the intended outcomes maximise potential outcomes and impacts Data management and sharing How will you manage and share data collected or acquired through the proposed research?

What the assessors are looking for in your response Provide a data management plan that clearly details how you will comply with UKRI’s published data sharing policy , which includes detailed guidance notes. Does your proposed research require the support and use of a facility? What the assessors are looking for in your response If you will need to use a facility, follow your proposed facility’s normal access request procedures.

Ensure you have prior agreement so that if you are offered funding, they will support the use of their facility on your project.

For each requested facility you will need to provide the: name of facility, copied and pasted from the facility information list (DOCX, 38KB) proposed usage or costs, or costs per unit where indicated on the facility information list confirmation you have their agreement where required Facilities should only be named if they are on the facility information list above.

If you will not need to use a facility, you will be able to indicate this in the Funding Service. Ethics and responsible research and innovation (RRI) What are the ethical or RRI implications and issues relating to the proposed work? If you do not think that the proposed work raises any ethical or RRI issues, explain why.

What the assessors are looking for in your response Demonstrate that you have identified and evaluated: the relevant ethical or responsible research and innovation considerations how you will manage these considerations You may demonstrate elements of your responses in visual form if relevant. Further details are provided in the Funding Service.

Genetic and biological risk Does your proposed research involve any genetic or biological risk?

What the assessors are looking for in your response In respect of animals, plants or microbes, are you proposing to: use genetic modification as an experimental tool, like studying gene function in a genetically modified organism release genetically modified organisms ultimately develop commercial and industrial genetically modified outcomes If yes, provide the name of any required approving body and state if approval is already in place.

If it is not, provide an indicative timeframe for obtaining the required approval. Identify the organism or organisms as a plant, animal or microbe and specify the species and which of the three categories the research relates to. Identify the genetic and biological risks resulting from the proposed research, their implications, and any mitigation you plan on taking.

Assessors will want to know you have considered the risks and their implications to justify that any identified risks do not outweigh any benefits of the proposed research. If this does not apply to your proposed work, please state ‘N/A’. Research involving the use of animals Does your proposed research involve the use of vertebrate animals or other organisms covered by the Animals Scientific Procedures Act?

What the assessors are looking for in your response If you are proposing research that requires using animals, download and complete the Animals Scientific Procedures Act template (DOCX, 74KB) , which contains all the questions relating to research using vertebrate animals or other Animals (Scientific Procedures) Act 1986 regulated organisms.

Studies proposing to use non-human primates, cats, dogs, equines or pigs will be assessed during NC3Rs review of research applications. Save it as a PDF. The Funding Service will provide document upload details when you apply.

If this does not apply to your proposed work, please state ‘N/A’. Upload as a single PDF ensuring it is no larger than 8MB. Conducting research with animals overseas Will any of the proposed animal research be conducted overseas?

What the assessors are looking for in your response If you are proposing to conduct overseas research, it must be conducted in accordance with welfare standards consistent with those in the UK, as in Responsibility in the use of animals in bioscience research, page 14 . Ensure all named applicants in the UK and overseas are aware of this requirement.

If your application proposes animal research to be conducted overseas, you must provide a statement in the text box. Depending on the species involved, you may also need to upload a completed template for each species listed.

Provide a statement to confirm that: all named applicants are aware of the requirements and have agreed to abide by them this overseas research will be conducted in accordance with welfare standards consistent with the principles of UK legislation the expectation set out in Responsibility in the use of animals in bioscience research will be applied and maintained appropriate national and institutional approvals are in place Overseas studies proposing to use non-human primates, cats, dogs, equines or pigs will be assessed during NC3Rs review of research applications.

Provide the required information by completing the template from the question ‘Research involving the use of animals’. For studies involving other species, select, download, and complete the relevant Word checklist or checklists from this list: Additional questions on the use of rodents overseas (DOCX, 49. 1KB) Additional questions on the use of rabbits overseas (DOCX, 49.

2KB) Additional questions on the use of sheep overseas (DOCX, 50. 9KB) Additional questions on the use of goats overseas (DOCX, 47. 3KB) Additional questions on the use of pigs overseas (DOCX, 51.

4KB) Additional questions on the use of cattle overseas (DOCX, 57. 0KB) Additional questions on the use of Xenopus laevis and Xenopus tropicalis overseas (DOCX, 57. 3KB) Save your completed template as a PDF and upload to the Funding Service.

If you use more than one checklist template, save it as a single PDF. The Funding Service will provide document upload details when you apply. If conducting research with animals overseas does not apply to your proposed work, please state ‘N/A’.

Upload as a single PDF ensuring it is no larger than 8MB. Research involving human participation Will the project involve the use of human subjects or their personal information? What the assessors are looking for in your response If you are proposing research that requires the involvement of human subjects, provide the name of any required approving body and whether approval is already in place.

Justify the number and the diversity of the participants involved, as well as any procedures. Provide details of any areas of substantial or moderate severity of impact. If this does not apply to your proposed work, you will be able to indicate this in the Funding Service.

Research involving human tissues or biological samples Does your proposed research involve the use of human tissues, or biological samples? What the assessors are looking for in your response If you are proposing work that involves human tissues or biological samples, provide the name of any required approving body and whether approval is already in place.

Justify the use of human tissue or biological samples specifying the nature and quantity of the material to be used and its source. If this does not apply to your proposed work, you will be able to indicate this in the Funding Service. How we will assess your application We will assess your application using the following process.

We will invite experts to review your application independently, against the specified criteria for this funding opportunity. You will not be able to nominate reviewers for applications on the new UK Research and Innovation (UKRI) Funding Service. Research councils will continue to select expert reviewers.

We are monitoring the requirement for applicant-nominated reviewers as we review policies and processes as part of the continued development of the new Funding Service. Following peer review, we will invite experts to use the evidence provided by reviewers and your applicant response to assess the quality of your application and rank it alongside other applications after which the panel will make a funding recommendation.

We aim to complete the assessment process within six months of receiving your application. We support the San Francisco declaration on research assessment and recognise the relationship between research assessment and research integrity. Find out about the UKRI principles of assessment and decision making .

Sharing data with co-funders We will need to share the application (including any personal information that it contains) with other research councils so that they can participate in the assessment process. For more information on how UKRI uses personal information, read UKRI’s privacy notice . We reserve the right to modify the assessment process as needed.

The assessment areas we will use are: Applicant and Team capability to deliver Ethics and responsible research and innovation (RRI) Find details of assessment questions and criteria under the ‘Application questions’ heading in the ‘How to apply’ section.

Get help with your application If you have a question and the answers aren’t provided on this page Important note: The Helpdesk is committed to helping users of the UK Research and Innovation (UKRI) Funding Service as effectively and as quickly as possible. In order to manage cases at peak volume times, the Helpdesk will triage and prioritise those queries with an imminent opportunity deadline or a technical issue.

Enquiries raised where information is available on the Funding Finder opportunity page and should be understood early in the application process (for example, regarding eligibility or content/remit of an opportunity) will not constitute a priority case and will be addressed as soon as possible.

For help and advice on costings and writing your proposal please contact your research office in the first instance, allowing sufficient time for your organisation’s submission process. For questions related to this specific funding opportunity please contact: eligibility: eligibility@bbsrc. ukri.

org scope and remit: remit@bbsrc. ukri. org IPA or LINK schemes: industry.

collaboration@bbsrc. ukri. org international agreements: inca@bbsrc.

ukri. org Any queries regarding the system or the submission of applications through