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Find similar grantsBRAIN Initiative: Data Knowledgebase Ecosystem and NeuroAI Integration is sponsored by National Institutes of Health (NIH). This NIH BRAIN Initiative topic seeks applications for interconnected Knowledgebase projects, including a data commons that federates established BRAIN data repositories.
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BRAIN Initiative: Data Knowledgebase Ecosystem and NeuroAI Integration | Grants & Funding U.S. Department of Health and Human Services National Institutes of Health BRAIN Initiative: Data Knowledgebase Ecosystem and NeuroAI Integration When beginning your next investigator-initiated application, consider the following NIH highlighted topic.
The area of science described below is of interest to the listed NIH Institutes, Centers, and Offices (ICOs). This is not a notice of funding opportunity (NOFO). Apply through an appropriate NIH Parent Funding Announcement or another broad NIH opportunity available on Grants.
gov . Learn how to interpret and use Highlighted Topics . Post Date: February 24, 2026 Expiration Date: September 29, 2027 The NIH Brain Research Through Advancing Innovative Neurotechnologies ® (BRAIN) Initiative strategically advances neuroscience to revolutionize our understanding of the human brain.
The Initiative seeks applications for an interconnected set of Knowledgebase projects including a data commons that will federate currently established BRAIN data repositories into a unified framework with three key research areas: Developing standardized cell-type taxonomies and spatial reference frameworks for cross-species brain mapping Creating quality-assured connectivity atlases with validated annotation tools for circuit-level analysis Integrating synchronized neural-behavioral data with cross-species ontologies to characterize brain-behavior relationships.
These federated resources will enable AI-powered cross-modal discovery using knowledge graphs and open data standards to accelerate predictive modeling and translation from pre-clinical models to human health applications.
The NIH BRAIN Initiative simultaneously seeks transformative NeuroAI approaches that leverage these integrated knowledgebase resources through three complementary research directions: Developing interpretable computational models that elucidate biological mechanisms across scales while maintaining cross-modal integration capabilities Advancing energy-efficient neuromorphic platforms that adapt to individual variations through real-time processing for research and health monitoring applications Establishing brain-body system frameworks to investigate embodied intelligence through integration of neuronal and non-neuronal cellular interactions with environmental contexts.
These NeuroAI innovations must demonstrate bidirectional knowledge exchange where biological principles inform brain-inspired computing architectures while computational tools drive mechanistic neuroscience discovery.
Applications should address critical gaps through data-driven approaches that advance reproducibility and transparency while maintaining BRAIN's leadership in interdisciplinary neuroscience and technology development for improving human health. The NIH BRAIN Initiative consists of the NIH Institutes and Centers identified below, unless otherwise indicated.
Central Scientific Contact: National Institute of Neurological Disorders and Stroke (NINDS) IC may dedicate funds available to support applications in this Topic area depending upon the availability of funds, the number of meritorious applications, and competing ICO priorities.
National Center for Complementary and Integrative Health (NCCIH) National Eye Institute (NEI) National Institute on Aging (NIA) National Institute on Alcohol Abuse and Alcoholism (NIAAA) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institute on Drug Abuse (NIDA) National Institute on Deafness and Other Communication Disorders (NIDCD) National Institute of Mental Health (NIMH) Office of Research on Women's Health (ORWH) The NIH Office of Research on Women's Health (ORWH) may co-fund meritorious applications in this topic area based on the availability of funds and alignment with research priorities in women's health.
This office does not award grants. Applications must be relevant to the objectives of at least one of the participating NIH Institutes and Centers listed in this topic. Elena Gorodetsky, M.
D. , Ph. D.
Victoria Shanmugam, MBBS, MRCP, FACR, CCD For technical issues E-mail OER Webmaster
According to the current listing, eligibility includes: See NIH Parent Funding Announcement for specific eligibility, generally open to academic, non-profit, and other research organizations. Confirm the full requirements in the official notice before applying.
Applications for BRAIN Initiative: Data Knowledgebase Ecosystem and NeuroAI Integration are due September 29, 2027. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
BRAIN Initiative: Data Knowledgebase Ecosystem and NeuroAI Integration is funded by National Institutes of Health (NIH). Verify program details on the funder's official page before applying.
Yes — this listing is flagged as national in scope, so applicants across the U.S. may apply, subject to the sponsor's other eligibility criteria.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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