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Questions about this NOFO ? Check the Frequently Asked Questions available at https://arpa -e. energy.
gov/faqs . For questions that have not already been answered, e mail ARPA -E-CO@hq. doe.
gov (with NOFO name and number in subject lin e). Problems with ARPA -E eXCHANGE? Email ExchangeHelp@hq.
doe. gov (with NOFO name and number in subject line).
## NOTICE OF FUNDING OPPORTUNITY ## ADVANCED RESEARCH PROJECTS AGENCY – ENERGY (ARPA -E) ## U.S. DEPARTMENT OF ENERGY # CATALYTIC APPLICATION TESTING FOR ACCELERATED # LEARNING CHEMISTRIES VIA HIGH -THROUGHPUT # EXPERIMENTATION AND MODELING EFFICIENTLY SBIR/STTR # (CATALCHEM -E SBIR/STTR ) Announcement Type: Initial Announcement Notice of Funding Opportunity No. DE -FOA -000350 6 Assistance Listing Number 81.
135 NOFO s are posted on ARPA -E eXCHANGE ( https://arpa -e-foa. energy. gov/ ), Grants.
gov (http://www. grants. gov/ ), and FedConnect ( https://www.
fedconnect. net/FedConnect/ ). Any modifications to the NOFO are also posted to these websites.
You can receive an e -mail when a modification is posted by registering with FedConnect as an interested party for this NOFO . It is recommended that you register as soon as possible after release of the NOFO to ensure that you receive timely notice of any modifications or other announcements. Questions about this NOFO ?
Check the Frequently Asked Questions available at https://arpa -e. energy. gov/faqs .
For questions that have not already been answered, e mail ARPA -E-CO@hq. doe. gov (with NOFO name and number in subject lin e).
Problems with ARPA -E eXCHANGE? Email ExchangeHelp@hq. doe.
gov (with NOFO name and number in subject line). BASIC INFORMATION ................................ ................................
................................ ................................ .........
- 5 - I. FUNDING OPPORTUNITY DESCRIPTION ................................ ................................
................................ ..... - 7 - A.
AGENCY OVERVIEW ................................ ................................ ................................
................................ ........... - 7 - B.
SBIR/STTR PROGRAM OVERVIEW ................................ ................................ ................................
...................... - 9 - C. PROGRAM OVERVIEW ................................
................................ ................................ ................................
. - 10 - 1. SUMMARY ................................
................................ ................................ ................................
............... - 10 - 2. TECHNICAL BACKGROUND ................................
................................ ................................ ...........................
- 10 - D. PROGRAM OBJECTIVES ................................ ................................
................................ ................................ - 15 - E.
REQUIRED TECHNICAL APPROACHES ................................ ................................ ................................
................... - 17 - F. TECHNICAL PERFORMANCE TARGETS ................................
................................ ................................ ..................
- 20 - 1. PHASE 1: WORKFLOW DEVELOPMENT USING REFERENCE CHEMISTRY ................................ ................................
- 21 - 2. PHASE 2: NEW CATALYST AND CHEMISTRY DISCOVERY ................................ ................................
.................... - 25 - 3. JUSTIFICATION TABLE ................................
................................ ................................ ................................
. - 27 - 4. SUMMARY OF PROJECT REQUIREMENTS ................................
................................ ................................ ........
- 27 - G. ADDITIONAL PROJECT REQUIREMENTS ................................ ................................
................................ ........... - 28 - H.
STATEMENT OF SUBSTANTIAL INVOLVEMENT ................................ ................................ ................................
... - 29 - I. FUNDING RESTRICTIONS ................................
................................ ................................ ................................
... - 30 - 1. ALLOWABLE COSTS ................................
................................ ................................ ................................
.... - 30 - 2. PRE -AWARD COSTS ................................
................................ ................................ ................................
... - 30 - 3. PATENT COSTS ................................
................................ ................................ ................................
.......... - 30 - 4. CONSTRUCTION ................................
................................ ................................ ................................
......... - 31 - 5. FOREIGN TRAVEL ................................
................................ ................................ ................................
....... - 31 - 6. PERFORMANCE OF WORK IN THE UNITED STATES ................................
................................ ............................ - 31 - 7.
PURCHASE OF NEW EQUIPMENT ................................ ................................ ................................
.................. - 31 - 8. TECHNOLOGY TRANSFER AND OUTREACH ................................
................................ ................................ ......
- 31 - 9. LOBBYING ................................ ................................
................................ ................................ ................
- 32 - 10. CONFERENCE SPENDING ................................ ................................
................................ ............................. - 32 - 11.
INDEPENDENT RESEARCH AND DEVELOPMENT COSTS ................................ ................................ .......................
- 33 - 12. BUY AMERICA REQUIREMENT FOR PUBLIC INFRASTRUCTURE PROJECTS ................................ ..............................
- 33 - 13. REQUIREMENT FOR FINANCIAL PERSONNEL ................................ ................................
................................ .... - 34 - 14.
PARTICIPANTS , COLLABORATING ORGANIZATIONS , AND CURRENT AND PENDING SUPPORT ................................ ... - 34 - 15.
PAYMENT OF FEE OR PROFIT ................................ ................................ ................................
....................... - 34 - II. ELIGIBILITY INFORMATION ................................
................................ ................................ ......................
- 36 - A. ELIGIBLE APPLICANTS ................................ ................................
................................ ................................ .......
- 36 - 1. SBIR ELIGIBILITY ................................ ................................
................................ ................................ .......
- 36 - 2. STTR ELIGIBILITY ................................ ................................
................................ ................................ ......
- 36 - 3. JOINT SBIR AND STTR ELIGIBILITY ................................ ................................
................................ ............... - 36 - B.
ELIGIBLE SUBRECIPIENTS ................................ ................................ ................................
................................ ... - 37 - 1.
RESEARCH INSTITUTIONS ................................ ................................ ................................
............................ - 37 - 2. OTHER PROJECT TEAM MEMBERS ................................
................................ ................................ ................
- 37 - 3. FOREIGN ENTITIES ................................ ................................
................................ ................................ .....
- 38 - C. ELIGIBLE PRINCIPAL INVESTIGATORS ................................ ................................
................................ ............... - 38 - 1.
SBIR ................................ ................................ ................................
................................ ....................... - 38 -Questions about this NOFO ?
Check the Frequently Asked Questions available at https://arpa -e. energy. gov/faqs .
For questions that have not already been answered, e mail ARPA -E-CO@hq. doe. gov (with NOFO name and number in subject lin e).
Problems with ARPA -E eXCHANGE? Email ExchangeHelp@hq. doe.
gov (with NOFO name and number in subject line). 2. STTR ................................
................................ ................................ ................................
...................... - 38 - D. FOREIGN PARTICIPATION ................................
................................ ................................ .............................
- 39 - 1. FOREIGN NATIONAL PARTICIPATION FROM COUNTRIES OF CONCERN ................................ ................................
. - 39 - 2. FOREIGN PARTICIPATION CONSIDERATIONS ................................
................................ ................................ ...
- 39 - E. ELIGIBILITY OF PRIOR SBIR AND STTR AWARDEES : SBA BENCHMARKS ON PROGRESS TOWARDS COMMERCIALIZATION . - 39 - F.
COMPLIANCE AND RESPONSIVENESS ................................ ................................ ................................
................... - 41 - G. LIMITATION ON NUMBER OF SUBMISSIONS ................................
................................ ................................ .....
- 41 - H. COST SHARING ................................ ................................
................................ ................................ ...........
- 41 - III. APPLICATION CONTENTS AND FORMAT ................................ ................................
.............................. - 42 - A. GENERAL APPLICATION CONTENT REQUIREMENTS ................................
................................ ................................ - 42 - 1.
MARKING OF CONFIDENTIAL INFORMATION ................................ ................................ ................................
... - 42 - 2. EXPORT CONTROL INFORMATION ................................
................................ ................................ .................
- 42 - B. CONCEPT PAPERS ................................ ................................
................................ ................................ ............
- 43 - 1. FIRST COMPONENT : CONCEPT PAPER ................................ ................................
................................ ............ - 43 - 2.
SECOND COMPONENT : SUMMARY SLIDE AND WORKFLOW TOPOLOGY ................................ ............................... - 43 - C.
FULL APPLICATIONS ................................ ................................ ................................
................................ .... - 44 - 1.
FIRST COMPONENT : TECHNICAL VOLUME ................................ ................................ ................................
...... - 44 - 2. SECOND COMPONENT : JUSTIFICATION TABLE ................................
................................ ................................ .
- 45 - 3. THIRD COMPONENT : LETTERS OF INTENT ................................ ................................
................................ ....... - 45 - 4.
FOURTH COMPONENT : SF -424 ................................ ................................ ................................
................... - 45 - 5. FIFTH COMPONENT : BUDGET JUSTIFICATION WORKBOOK /SF -424A ................................
................................ . - 46 - 6.
SIXTH COMPONENT : SUMMARY FOR PUBLIC RELEASE ................................ ................................ ......................
- 46 - 7. SEVENTH COMPONENT : SUMMARY SLIDE AND WORKFLOW TOPOLOGY ................................ ..............................
- 46 - 8. EIGHTH COMPONENT : BUSINESS ASSURANCES & DISCLOSURES FORM ................................ ................................
- 47 - 6. NINTH COMPONENT : SBIR. GOV COMPANY REGISTRATION ................................
................................ .............. - 47 - 7.
TENTH COMPONENT : ADDITIONAL OWNERSHIP CERTIFICATIONS ................................ ................................ .......
- 47 - D. REPLIES TO REVIEWER COMMENTS ................................ ................................
................................ ................ - 47 - IV.
SUBMISSION REQUIREMENTS AND DEADLINES ................................ ................................ ...................
- 49 - A. COMPLETION OF SBIR. GOV COMPANY REGISTRATION ................................
................................ .......................... - 49 - B.
UNIQUE ENTITY IDENTIFIER AND SAM REGISTRATION ................................ ................................ ...........................
- 49 - C. USE OF ARPA -E EXCHANGE ................................ ................................
................................ ...................... - 50 - D.
REQUIRED DOCUMENTS CHECKLIST AND DEADLINES ................................ ................................ .........................
- 51 - E. COMPLIANCE ................................ ................................
................................ ................................ ..................
- 52 - F. INTERGOVERNMENTAL REVIEW ................................ ................................
................................ ......................... - 52 - V.
APPLICATION REVIEW INFORMATION ................................ ................................ ................................
..... - 53 - A. RESPONSIVENESS ................................
................................ ................................ ................................
............ - 53 - 1. TECHNICAL RESPONSIVENESS REVIEW ................................
................................ ................................ ...........
- 53 - 2. SUBMISSIONS SPECIFICALLY NOT OF INTEREST ................................ ................................
................................ . - 54 - B.
REVIEW CRITERIA ................................ ................................ ................................
................................ ............ - 54 - 1.
CRITERIA FOR CONCEPT PAPERS ................................ ................................ ................................
................... - 54 - 2. CRITERIA FOR FULL APPLICATIONS ................................
................................ ................................ ................
- 55 - 3. CRITERIA FOR REPLIES TO REVIEWER COMMENTS ................................ ................................
............................ - 56 - C. PROGRAM POLICY FACTORS ................................
................................ ................................ .........................
- 56 -Questions about this NOFO ? Check the Frequently Asked Questions available at https://arpa -e. energy.
gov/faqs . For questions that have not already been answered, e mail ARPA -E-CO@hq. doe.
gov (with NOFO name and number in subject lin e). Problems with ARPA -E eXCHANGE? Email ExchangeHelp@hq.
doe. gov (with NOFO name and number in subject line). D.
REVIEW AND SELECTION PROCESS ................................ ................................ ................................
................. - 57 - 1. CONCEPT PAPERS ................................
................................ ................................ ................................
...... - 57 - 2. FULL APPLICATIONS ................................
................................ ................................ ................................
... - 58 - 3. REPLY TO REVIEWER COMMENTS ................................
................................ ................................ .................
- 58 - 4. PRE -SELECTION CLARIFICATIONS AND “D OWN -SELECT ” PROCESS ................................ ................................
...... - 58 - 5. SELECTION FOR AWARD NEGOTIATIONS ................................
................................ ................................ ........
- 58 - E. ARPA -E REVIEWERS ................................ ................................
................................ ................................ .......
- 59 - F. ARPA -E SUPPORT CONTRACTORS ................................ ................................
................................ ..................... - 59 - G.
RISK REVIEW ................................ ................................ ................................
................................ .............. - 60 - VI.
AWARD NOTICES AND AWARD TYPES ................................ ................................ ................................
. - 61 - A. AWARD NOTICES ................................
................................ ................................ ................................
............ - 61 - 1. REJECTED SUBMISSIONS ................................
................................ ................................ .............................
- 61 - 2. CONCEPT PAPER NOTIFICATIONS ................................ ................................
................................ .................. - 61 - 3.
FULL APPLICATION NOTIFICATIONS ................................ ................................ ................................
............... - 61 - B. PRE -AWARD COSTS ................................
................................ ................................ ................................
......... - 62 - C. RENEWAL AWARDS ................................
................................ ................................ ................................
..... - 63 - D. FUNDING AGREEMENTS ................................
................................ ................................ ...............................
- 63 - VII. POST -AWARD REQUIREMENTS AND ADMINISTRATION ................................ ................................
...... - 64 - A. NATIONAL POLICY REQUIREMENTS ................................
................................ ................................ ....................
- 64 - 1. NATIONAL POLICY ASSURANCES ................................ ................................
................................ ................... - 64 - 2.
ENVIRONMENTAL IMPACT QUESTIONNAIRE ................................ ................................ ................................
... - 64 - B. ADMINISTRATIVE REQUIREMENTS ................................
................................ ................................ ......................
- 65 - 1. INTELLECTUAL PROPERTY AND DATA MANAGEMENT PLANS ................................ ................................
............. - 65 - 2. U.S. COMPETITIVENESS ................................
................................ ................................ ..............................
- 65 - 3. NONDISCLOSURE AND CONFIDENTIALITY AGREEMENTS REPRESENTATIONS ................................ ..........................
- 67 - 4. INTERIM CONFLICT OF INTEREST POLICY FOR FINANCIAL ASSISTANCE ................................ ................................
.. - 68 - 5. COMPLIANCE AUDIT REQUIREMENT ................................
................................ ................................ ..............
- 68 - 6. RESEARCH SECURITY TRAINING REQUIREMENT ................................ ................................
............................... - 68 - C. REPORTING ................................
................................ ................................ ................................
................ - 69 - 1. FRAUD , WASTE , AND ABUSE ................................
................................ ................................ .......................
- 69 - 2. COMMERCIALIZATION PLAN AND SOFTWARE REPORTING ................................ ................................
................. - 69 - VIII. OTHER INFORMATION ................................
................................ ................................ .........................
- 70 - A. TITLE TO SUBJECT INVENTIONS ................................ ................................
................................ .......................... - 70 - B.
GOVERNMENT RIGHTS IN SUBJECT INVENTIONS ................................ ................................ ................................
.... - 70 - 1. GOVERNMENT USE LICENSE ................................
................................ ................................ ........................
- 71 - 2. MARCH -IN RIGHTS ................................ ................................
................................ ................................ ....
- 71 - C. RIGHTS IN TECHNICAL DATA ................................ ................................
................................ ......................... - 71 - D.
PROTECTED PERSONALLY IDENTIFIABLE INFORMATION ................................ ................................ ......................
- 72 - IX. GLOSSARY ................................ ................................
................................ ................................ ...........
- 73 -Questions about this NOFO ? Check the Frequently Asked Questions available at https://arpa -e. energy.
gov/faqs . For questions that > have not already been answered, e mail ARPA -E-CO@hq. doe.
gov (with NOFO name and number in subject lin e). Problems with > ARPA -E eXCHANGE? Email ExchangeHelp@hq.
doe. gov (with NOFO name and number in subject line). Notice of Funding Opportunity (NOFO) Issue Date: November 14, 2024 Deadline for Concept Paper Questions to ARPA -E-CO@hq.
doe. gov : 5 PM ET, Dece mber 10, 2024 Submission Deadline for Concept Papers: 9:30 AM ET, December 17, 2024 Anticipated Timeframe for Encourage/Discourage Notifications: March, 2025 Deadline for Full Application Questions to ARPA -E-CO@hq. doe.
gov : 5 PM ET, TBD Submission Deadline for Full Applications: 9:30 AM ET, TBD Expected Reviewer Comment Release Date: 5 PM ET, TBD Submission Deadline for Replies to Reviewer Comments: 5 PM ET, TBD Anticipated Timeframe for Selection Notifications: May 2025 Anticipated Timeframe for Award: August 2025 Anticipated Period of Performance: August 2025 – August 2028 Approximately $ 35 million, subject to the availability of appropria ted funds to be shared between NOFOs DE -FOA -0003505 and DE -FOA -0003506.
ARPA -E anticipates making approximately 10 -12 awards between NOFOs DE -FOA - 0003505 and DE -FOA -0003506. ARPA -E may issue one, multiple, or no awards. The Federal share of awards may vary between $2.
5 million and $3. 5 million. • Questions and answers (Q&As) about ARPA -E and this specific NOFO: http://arpa -e.
energy. gov/faq . • Send other questions about the NOFO to: ARPA -E-CO@hq.
doe. gov . • Send questions about use of ARPA -E eXCHANGE to: ExchangeHelp@hq.
doe. gov . Upon the issuance of a NOFO, only the Grants Officer via ARPA -E-CO@hq.
doe. gov may communicate with Applicants. This “quiet period” remains in effect until ARPA -E’s public announcement of project selections.
Emails sent to other email addresses will be disregarded. Catalyst discovery, development, and optimization has been critical to the commodity fuels and chemical industry, but it can take years to develop a durable commercial catalyst. Further, the development process often relies on experience, intuition, engine ering judgement, and experimental trial and error across multiple length scales.
Recent advancements in high - throughput experimentation (HTE) methods using artificial intelligence (AI) and machine learning (ML) present a significant and unique opportunity to accelerate the design and development cycle for catalyst research and development (R&D) workflows.
The CATALCHEM -E program seeks to disrupt and accelerate the traditional heterogeneous catalyst R&D workflows spanning from rational design of research catalyst powders to synthesis, characterization , and reactor -scale testing of technical catalyst composites. These novel workflows will be developed in two phases of 18 months each. In Phase 1 , teams will Questions about this NOFO ?
Check the Frequently Asked Questions available at https://arpa -e. energy. gov/faqs .
For questions that > have not already been answered, e mail ARPA -E-CO@hq. doe. gov (with NOFO name and number in subject lin e).
Problems with > ARPA -E eXCHANGE? Email ExchangeHelp@hq. doe.
gov (with NOFO name and number in subject line). tightly coupl e state -of -the -art HTE methods with advanced tools and techniques in AI/ML to achieve more than a ten -time acceleration in the catalyst development cycle. Further impact will be realized in Phase 2 by utilizing the tools developed in Phase 1 to achieve novel catalyst - reaction discovery and co -design.
The program encourages the development of closed -loop and ot her promising, automated workflow topologies that enable inverse design of heterogenous catalysts. Other key program goals include synthe sis of new “drop -in” manufacturable technical catalysts in engineered forms at the kilogram scale for thermochemical or electrochemical reactor systems, generation of high -quality databases, and creation of AI/ML models.
Various communities, such as subject matter experts in HTE, AI/ML, computational modeling and simulation, traditional experimental catalysis, industrial catalysis , and manufacturing must come together in an unprecedented way to achieve these ambitious, game -changing program goals. Questions about this NOFO ? Check the Frequently Asked Questions available at https://arpa -e.
energy. gov/faqs . For questions that > have not already been answered, e mail ARPA -E-CO@hq.
doe. gov (with NOFO name and number in subject lin e). Problems with > ARPA -E eXCHANGE?
Email ExchangeHelp@hq. doe. gov (with NOFO name and number in subject line).
## I. FUNDING OPPORTUNITY DESCRIPTION The Advanced Research Projects Agency – Energy (ARPA -E), an organization within the Department of Energy (DOE), is chartered by Congress in the America COMPETES Act of 2007 (P. L.
110 -69), as amended by the America COMPETES Reauthorization Act of 2010 (P. L. 111 - 358), as further amended by the Energy Act of 2020 (P.
L.
116 -260): “(A) to enhance the economic and energy security of the United States through the development of energy technologies that — (i) reduce imports of energy from foreign sources; (ii) reduce energy -related emissions, including greenhouse gases; (iii) improve the energy efficiency of all economic sectors; (iv) provide transformative solutions to improve the management, clean -up, and disposal of radioactive waste and spent nuclear fuel; and (v) improve the resilience, reliability, and security of infrastructure to produce, deliver, (B) to ensure that the United States maintains a technological lead in developing and deploying advanced energy technologies.
” ARPA -E issues this Notice of Funding Opportunity (NOFO ) under its authorizing statute codified at 42 U.S.C. § 16538. The NOFO and any cooperative agreements or grants made under this NOFO are subject to 2 C.
F. R. Part 200 as supplemented by 2 C.
F. R. Part 910.
ARPA -E funds research on, and the development of, transformative science and technology solutions to address the energy and environmental missions of the Department. The agency focus es on technologies that can be meaningfully advanced with a modest investment over a defined period of time in order to catalyze the translation from scientific discovery to early - stage technology.
For the latest news and information about ARPA -E, its programs and the research projects currently supported, see: http://arpa -e. energy. gov/ .
ARPA -E funds transformational research. Existing energy technologies generally progress on established “learning curves” where refinements to a technology and the economies of scale that accrue as manufacturing and distribution develop drive improvements to the cost/performance metric in a gradual fashion.
This continual improvement of a technology is important to its increased commercial deployment and is appropriately the focus of the private sector or the applied technology offices within DOE. In contras t, ARPA -E supports transformative research that has the potential to create fundamentally new learning curves.
ARPA -E technology projects typically start with cost/performance estimates well above the level of an incumbent technology. Given the high risk inherent in these projects, many will fail to progress, but some may succeed in generating a new learning curve with a projected cost/performance metric that is significantly better than that of the incumbent technology.
ARPA -E will provide support at the h ighest funding level only for submissions with significant Questions about this NOFO ? Check the Frequently Asked Questions available at https://arpa -e. energy.
gov/faqs . For questions that > have not already been answered, e mail ARPA -E-CO@hq. doe.
gov (with NOFO name and number in subject lin e). Problems with > ARPA -E eXCHANGE? Email ExchangeHelp@hq.
doe. gov (with NOFO name and number in subject line). technology risk, aggressive timetables, and careful management and mitigation of the ARPA -E funds technology with the potential to be disruptive in the marketplace .
The mere creation of a new learning curve does not ensure market penetration. Rather, the ultimate value of a technology is determined by the marketplace, and impactful technologies ultimately become disruptive – that is, they are widely adopted and displace existing technologies from the marketplace or create entirely new markets.
ARPA -E understands that definitive proof of market disruption takes time, particularly for energy technologies. Therefore, ARPA -E funds the development of technologies that, if technically successful, have clear disruptive potential, e.g., by demonstrating capability for manufacturing at competitive cost and deployment at scale. ARPA -E funds applied research and development (R&D) .
The Office of Management and Budget defines “applied research” as an “original investigation undertaken in order to acquire new knowledge…directed primarily towards a specific practical aim or objective” and defines “experimental development” as “creative and systematic work, drawing on knowledge gained from research and practical experience, which is directed at producing new products or processes or improving existing products or processes .
” 1 Applicants interested in receiving financial assistance for basic research (defined by the Office of Management and Budget as “experimental or theoretical work undertaken primarily to acquire new knowledge of the underlying foundations of phenomena and observable facts”) 1 should contact the DOE’s Office of Science ( http://science. energy. gov/ ).
Office of Science national scientific user facilities (http://science. energy. gov/user -facilities/ ) are open to all researchers, including ARPA -E Applicants and awardees.
These facilities provide advanced tools of modern science including accelerators, colliders, supercomputers, light sources and neutron sources, as well as facilities for studying the nanoworld, the environment, and the atmosphere.
Projects focused on early - stage R&D for the improvement of technology along defined roadmaps may be more appropriate for support through the DOE applied energy offices including: the Office of Energy Efficiency and Renewable Energy ( http://www. eere. energy.
gov/ ), the Office of Fossil Energy and Carbon Management ( https://www. energy. gov/fecm/office -fossil -energy -and -carbon - management ), the Office of Nuclear Energy ( http://www.
energy. gov/ne/office -nuclear -energy ), and the Office of Electricity ( https://www. energy.
gov/oe/office -electricity ). ARPA -E encourages submissions stemming from ideas that still require proof -of -concept R&D efforts as well as those for which some proof -of -concept demonstration already exists. Submissions can propose a project with the end deliverable being an extremely creative, but > 1OMB Circular A -11 (https://www.
whitehouse. gov/wp -content/uploads/2018/06/a11_web_toc. pdf), Section 84, Questions about this NOFO ?
Check the Frequently Asked Questions available at https://arpa -e. energy. gov/faqs .
For questions that have not already been answered, e mail ARPA -E-CO@hq. doe. gov (with NOFO name and number in subject lin e).
Problems with ARPA -E eXCHANGE? Email ExchangeHelp@hq. doe.
gov (with NOFO name and number in subject line). ## B. SBIR/STTR PROGRAM OVERVIEW The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs are Government -wide programs authorized under Section 9 of the Small Business Act (15 U.S.C.
§ 638).
The objectives of the SBIR program are to (1) stimulate technological innovation in the private sector, (2) strengthen the role of Small Business Concerns in meeting Federal R&D needs, (3) increase private sector commercialization of innovations derived f rom Federal R&D activities, (4) foster and encourage participation by socially and economically disadvantaged and women -owned Small Business Concerns, and (5) improve the return on investment from Federally funded research and economic benefits to the Nati on.
The objective of the STTR program is to stimulate cooperative partnerships of ideas and technologies between Small Business Concerns and partnering Research Institutions through Federally ARPA -E administers a joint SBIR/STTR program in accordance with the Small Business Act and the SBIR and STTR Policy Directive issued by the U.S. Small Business Administration (SBA).
3 ARPA -E provides SBIR/STTR funding in three phases (Phase I, Phase II, and Phase IIS). Applicants must apply for a Combined Phase I/II Award or a Combined Phase I/II/IIS Award. Combined Phase I/II and I/II/IIS Awards are intended to develop transformational technologies with disruptive commercial potential.
Such commercial potential may be evidenced by (1) the likelihood of follow -on funding by private or non -SBIR/STTR sources if the project is successful, or (2) the Small Business Concern's record of successfully commercializing technologies developed under prior SBIR/STTR awards. Phase IIS awards are a “sequential” (i.e., additional) Phase II award, intended to allow the continued development of promising energy technologies.
Combined Phase I/II/IIS awards may be funded up to $ 4,505,859 . Funding amounts will be consistent with the Phase I and Phase II limits posted on SBIR. gov website.
4 ARPA -E reserves the right to select all or part of a proposed project (i.e., only Phase I, or only Phase I and Phase II). In the event that ARPA -E selects Phase I only or Phase I/II only, then the maximum award amount for a Phase I award is $ 314,363 and the maximum amount for a Phase I/II award is $2, 410,111 .
> 2Research Institutions include FFRDCs, nonprofit educational institutions, and other nonprofit research > organizations owned and operated exclusively for scientific purposes.
Eligible Research Institutions must maintain > a place of business in the United States, operate primarily in the United States, or make a significant contribution > to the U.S. economy through the payment of taxes or use of American products, materials, or la bor. > 3See 8 8Fed. Reg.
19704 (May 3, 2023 )or SBIR. gov file at SBIR and STTR Policy Directive -May 2023 . > 4For current SBIR and STTR Phase I and Phase II funding amounts, see https://legacy.
www. sbir. gov/about .
Phase > IIS funding amounts are equal to Phase II funding amounts for both SBIR and STTR awards. Questions about this NOFO ? Check the Frequently Asked Questions available at https://arpa -e.
energy. gov/faqs . For questions that have not already been answered, e mail ARPA -E-CO@hq.
doe. gov (with NOFO name and number in subject lin e). Problems with ARPA -E eXCHANGE?
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The Catalytic Application Testing for Accelerated Learning Chemistries via High -throughput Experimentation and Modeling Efficiently (CATALCHEM -E) program aims to disrupt and accelerat e the design and development cycle for heterogeneous catalyst R&D workflows . The program will span from rational material discovery to synthesis and final reactor testing.
These novel workflows will be developed by coupling the latest advancements in artificial intelligence (AI) and machine learning (ML) with high -throughput ex perimentation (HTE) to verifiably complete 10 –15 years of traditional catalysis R&D work wi thin 12 –18 months , thus achieving more than a ten -time acceleration in the catalyst development cycle.
5 The program will then use the se new tools to discover and optimize catalytic chemistries relevant to ARPA -E’s goals.
These new chemistries will ultimately help advance the objective of net -zero carbon emissions Innovations developed under the CATALCHEM -E program will involve: • Future refinery relevant or other next -generation feedstocks such as hydrogen (H 2), nitrogen (N 2), oxygen (O 2), water (H 2O), carbon dioxide (CO 2), methane (CH 4), ammonia (NH 3), methanol (MeOH), ethanol (EtOH), bio -intermediates (C xHyOz), waste plastics, and triglycerides (TAGs ); and • Products like ethylene (C2=) and p ropylene (C3=) as low carbon monomers , and sustainable aviation fuel (SAF), diesel, and syngas as distillate range hydrocarbons.
## 2. TECHNICAL BACKGROUND The DOE has set major energy and emissions goals for establishing a net -zero sustainable hydrogen and managed carbon economy within the next few decades . 7,8,9 A feasible t ransition to this economy by 2050 will require new thermochemical and electrochemical catalytic processes to produce low -emission chemicals, fuels , and materials.
Many of the heterogenous catalysts developed to meet 2050 goals have challenges related to throughput, single -pass yield, lifetime, stability, energy requirements (i.e. , heat, electricity) , manufacturability, supply > 5Sharon Mitchell, Nina -Luisa Michels, and Javier Pérez -Ramírez, “From Powder to Technical Body: The > Undervalued Science of Catalyst Scale Up,” Chemical Society Reviews 42, no. 14 (June 21, 2013): 6094 –6112 , > https://doi.
org/10. 1039/C3CS60076A . > 6U.
S. Department of Energy. “ How we’re moving to net -zero by 2050 ,” (April 2021 ).
> https://www. energy. gov/articles/how -were -moving -net -zero -2050 .
> 7U. S. Department of Energy.
“Hydrogen shot,” accessed October 23, 2024. > https://www. energy.
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> https://www. energy. gov/fecm/carbon -negative -shot .
Questions about this NOFO ? Check the Frequently Asked Questions available at https://arpa -e. energy.
gov/faqs . For questions that > have not already been answered, e mail ARPA -E-CO@hq. doe.
gov (with NOFO name and number in subject lin e). Problems with > ARPA -E eXCHANGE? Email ExchangeHelp@hq.
doe. gov (with NOFO name and number in subject line). chain security , and cost.
10 To solve these issues in a timely manner, new laboratory -scale powder research catalysts must be quickly discovered, formulated, compounded, and developed into commercial -ready, formed technical catalysts . An overview of the traditional catalysis R&D workflows for research and technical catalyst development is shown in Figure 1 . > Figure 1.
An overview of the traditional catalysis R&D workflows for research and technical catalyst development , > which typically takes 10 –15 years from conception to pilot -scale testing. These conventional workflows largely rely on experience, intuition, engineering judgement, and experimental trial and error, followed by long -term pilot -scale performance testing campaigns to derisk the technologies .
Additionally, the transfer of research catalyst knowledge and data to the industrial technical catalyst development community must take place for successful Research Catalyst Development (State -of -the -Art): Traditional lab oratory -scale research cataly st R&D workflows are based on rational surface science, synthesis, characterization , pre - treatment, and activity testing of new materials.
Research catalysts are typically synthesized in powder form at milligram -to -gram quantities and tested over relatively short time periods (hours -to -days) for material compositional screening purposes .
5 Many of these laboratory -scale prepared materials struggle to meet the first -tier performance targets set by catalyst manufacturers (e.g. , yield, durability, stability, lifetime) or are too expensive to risk developing into a technical catalyst .
Consequently, for some novel materials, the R&D cycle for powder research catalysts focuse s on reactive surface fundamentals and the scientific discovery process can take decades to complete. > 10 Yix iao Wang et al. , “Catalytic Processes to Accelerate Decarbonization in a Net‐Zero Carbon World,” > ChemSusChem 15, no. 24 (December 20, 2022): e202201290 ,https://doi.
org/10. 1002/cssc. 202201290 .
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gov/faqs . For questions that > have not already been answered, e mail ARPA -E-CO@hq. doe.
gov (with NOFO name and number in subject lin e). Problems with > ARPA -E eXCHANGE? Email ExchangeHelp@hq.
doe. gov (with NOFO name and number in subject line). In the past, experimental attempts to accelerate these R&D cycles involved brute force, combinatorial synthesis , and screening of powders to explore compositional space .
These techniques were hindered by scale (microgram -to -milligram), reactor geometry , and the rational material design challenge of covering the vast compositional space across the periodic table with just human experience and intuition.
Thus, the latter challenge was addressed using in -silico approaches le veraging high -performance computing hardware resources to solve ab initio chemistry methods like density functional theory (DFT).
Although these approaches have traditionally been limited by computational time, calculation accuracy, and lack of connection to synthesis procedures, commercial technology organizations specializing in software platforms have recently made significant strides in accelerating these techniques.
11 ,12 Technical Catalyst Development (State -of -the -Art): On the other hand, commercial -scale industrial catalysis researchers follow materials development workflows , taking months -to - years . Whereas laboratory
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On September 21, 2026 DOE selected 21 projects under DE-FOA-0003472 — five EGS field tests and 16 exploration wells — for up to $99 million of a $171.5 million authorization. The solicitation is structured to reopen for up to 72 months on roughly annual cycles. Here is how to position for the next one.
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