Chronic, Noncommunicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award

Chronic, Noncommunicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award is sponsored by National Institutes of Health (NIH) Fogarty International Center. This program supports collaborative research training between institutions in the U. S.

and Low and Middle-Income Countries (LMICs) to build research capacity in chronic, noncommunicable diseases and disorders across the lifespan.

Expired PAR-21-230: Chronic, Non-Communicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award (NCD-LIFESPAN) (D43 Clinical Trial Optional) This notice has expired. Check the NIH Guide for active opportunities and notices. Department of Health and Human Services Part 1.

Overview Information Participating Organization(s) National Institutes of Health ( NIH ) Components of Participating Organizations Fogarty International Center ( FIC ) National Institute on Alcohol Abuse and Alcoholism ( NIAAA ) National Institute of Dental and Craniofacial Research ( NIDCR ) National Institute of Mental Health ( NIMH ) National Institute of Neurological Disorders and National Center for Complementary and Integrative Health ( NCCIH ) National Institute on Aging ( NIA ) All applications to this funding opportunity announcement should fall within the mission of the Institutes/Centers.

The following NIH Offices may co-fund applications assigned to those Institutes/Centers.

Division of Program Coordination, Planning and Strategic Initiatives, Office of Disease Prevention ( ODP ) Office of Research on Women's Health ( ORWH ) Special Note : Applicants should carefully note which ICs participate in this announcement and view their respective areas of research interest and requirements in Section I under "Specific Interests of the FOA Sponsors".

Consultation with NIH staff contacts before submitting an application is strongly encouraged (see Section VII. Agency Contacts). Funding Opportunity Title Chronic, Non-Communicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award (NCD-LIFESPAN) (D43 Clinical Trial Optional) D43 International Research Training Grants March 11, 2022 - This PAR has been reissued as PAR-22-104 .

October 28, 2021 - Reminder: FORMS-G Grant Application Forms & Instructions Must be Used for Due Dates On or After January 25, 2022 - New Grant Application Instructions Now Available. See Notice NOT-OD-22-018 . September 13, 2021 - Updates to the Non-Discrimination Legal Requirements for NIH Recipients.

See Notice August 5, 2021 - New NIH "FORMS-G" Grant Application Forms and Instructions Coming for Due Dates on or after January 25, 2022. August 5, 2021 - Update: Notification of Upcoming Change in Federal-wide Unique Entity Identifier Requirements. See Notice NOT-OD-21-170 April 20, 2021 - Expanding Requirement for eRA Commons IDs to All Senior/Key Personnel.

See Notice NOT-OD-21-109 June 15, 2021 - Notice of Participation of the National Institute on Aging (NIA) in PAR-21-230. See Notice NOT-AG-21-027 . Funding Opportunity Announcement (FOA) Number Companion Funding Opportunity See Section III.

3. Additional Information on Eligibility. Assistance Listing Number(s) 93.

989, 93. 242, 93. 213, 93.

121, 93. 853, 93. 313, 93.

273, 93. 866 Funding Opportunity Purpose This funding opportunity announcement (FOA) encourages applications for the Chronic, Non-Communicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award (NCD-LIFESPAN) D43 program for institutional research training programs in low-and middle-income countries (LMICs, as defined by the World Bank classification system).

Applications may be for collaborations between institutions in the U. S and an eligible LMIC or may involve just LMIC institutions if there is a previous track record of externally funded research and/or research training programs by the lead LMIC institution.

The proposed institutional research training program is expected to sustainably strengthen the NCD research capacity of the LMIC institutions, and to train in-country experts to develop and conduct research on NCDs across the lifespan, with the long-range goal of developing and implementing evidence-based interventions relevant to their countries. Interdisciplinary research training that cuts across NCDs is encouraged.

However, for more topical applications, the main focus of research training covered in the application must be relevant to the mission and/or interests of at least one of the participating NIH ICs, other than FIC, as stated by each in this FOA. Other NCD topics and types of training may be included as secondary and complementary focus areas.

This Funding Opportunity Announcement (FOA) allows appointment of Trainees (D43) proposing to serve as the lead investigator of an independent clinical trial; or proposing a separate ancillary clinical trial; or proposing to gain research experience in a clinical trial led by another investigator, as part of their research and career development.

Open Date (Earliest Submission Date) Letter of Intent Due Date(s) 30 days before receipt date Renewal / Resubmission / Revision (as allowed) New Date March 11, 2022 per issuance of PAR-22-104 . (Original Expiration Date: July 14, 2023 ) Required Application Instructions Conformance to all requirements (both in the Application Guide and the FOA) is required and strictly enforced.

Applicants must read and follow all application instructions in the Application Guide as well as any program-specific instructions noted in Section IV . When the program-specific instructions deviate from those in the Application Guide, follow the program-specific instructions. Applications that do not comply with these instructions may be delayed or not accepted for review.

Part 1. Overview Information Part 2. Full Text of Announcement Section I.

Funding Opportunity Description Section II. Award Information Section III. Eligibility Information Section IV.

Application and Submission Information Section V. Application Review Information Section VI. Award Administration Information Section VII.

Agency Contacts Section VIII. Other Information Part 2. Full Text of Announcement Section I.

Funding Opportunity Description The Fogarty International Center ( FIC ), together with the participating Institutes Centers and Offices: National Institute of Mental Health ( NIMH ), National Institute of Neurological Disorders and Stroke ( NINDS ), National Center for Complementary and Integrative Health ( NCCIH ), National Institute of Dental and Craniofacial Research ( NIDCR ), National Institute on Alcohol Abuse and Alcoholism ( NIAAA ), Office of Womens Health Research ( ORWH ), and Office of Disease Prevention ( ODP ) , encourages applications for the Chronic, Non-Communicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award (NCD-LIFESPAN) D43 program for institutional research training programs in low- and middle-income countries (LMICs, as defined by the World Bank classification system).

The application must propose a collaborative research training program in an LMIC involving either a U.S. institution and institution(s) in an LMIC or applications developed and submitted directly by LMIC institutions with substantial research and research training program experience to work with LMIC institutions with less capacity.

Programs must sustainably strengthen the capacity of LMIC institutions and investigators to conduct research on NCDs. Sustainable NCD research capacity is known to require a critical mass of scientists and health research professionals with in-depth scientific expertise and complementary leadership skills that enable them to conduct independent, internationally recognized NCD research relevant to the health priorities of their country.

This NCD-LIFESPAN program supports institutional research training awards for training programs designed to strengthen the capacity of the LMIC institution(s) to support independent research through the education and career development of individual researchers and key personnel. The trainees are expected to contribute to the research capacity in the LMIC upon completion of their training.

New research training programs are expected to focus on collaboration with a single LMIC institution as the major partner unless that collaboration for research training is already well-established at the LMIC site to the extent that outreach to other sites can be well-justified.

The ultimate goal is for the LMICs to run their own research training programs so all applications originating from the US institution must include plans to transition research training capabilities and management to the foreign site over the course of the grant period. Renewal applications from the US institution must also justify the continued need for leadership by the US awardee institution .

Applicants with well-established programs at the LMIC site may reach out to form research training networks to develop the research capacity of other LMIC institutions. The long-range goal is to provide a solid foundation in LMICs for development and implementation of evidence-based interventions, relevant to NCD's across the lifespan.

Sufficient evidence may exist upon which to base research for interventions and implementation strategies. However, often the evidence base is not well developed or not relevant to the given country or culture.

Therefore, training across the spectrum of research disciplines is encouraged as needed, from basic biomedical, behavioral and social science to clinical and applied sciences, including translational and implementation science that emphasizes the resources, context and needs of multiple stakeholders in local settings.

Special Program Objectives and Considerations The objectives of the NCD-LIFESPAN research training program are: To strengthen the capacity of LMIC institutions to conduct NCD research and to train a cadre of experts who can assess the magnitude, etiology of, interventions for and other aspects of NCDs.

Over time, the goal is for these institutions to become national, regional and international centers of expertise in NCD research; To support multidisciplinary research training in basic through translation and implementation science to address NCDs; To develop a cadre of research experts who are most likely to contribute to science advances and affect clinical practice and public health policy in their country; To support training-related research (degree-related or mentored research projects) that is directly relevant to the health priorities of the LMIC and to global health; To strengthen the research and research training capacity required for success by building on existing research and public health programs in the LMIC; To integrate, whenever possible, with other efforts to strengthen core research support capabilities needed to manage research and research training grants at the LMIC institution: including expertise in ethics and compliance issues, protection for human subjects, animal welfare, fiscal management, budgeting, program and grants administration, grant and report writing, preparation of scientific manuscripts, information technologies, technology transfer and management of intellectual property, data management, and Internet connectivity; To build on established research training programs to network for research training among institutions within a country and regionally between countries.

All applications to this program should have a central NCDs across the lifespan-related theme or focus although the theme may be as narrow or broad as deemed appropriate for the goals outlined in the FOA. The specific NCDs that may be addressed must be relevant to the stated interests of the participating NIH institutes, centers and offices (see "Specific Interests of the FOA Sponsors" section).

Research training programs are especially encouraged: That are relevant across NCDs in the target LMIC(s) That emphasize research training for lifecycle studies and early life determinants of chronic diseases (including genetic, epigenetic, environmental and lifestyle factors), co-morbid conditions and common risk factors and interventions relevant to multiple NCD conditions, their prevention and treatment.

For training in translation and implementation research for NCDs in general. The programs are expected to both support trainees to conduct research and, as appropriate and needed, to go beyond traditional training models to develop multifaceted and novel training paradigms targeted to the special needs of LMIC investigators and institutions.

Where well-established research and/or research training programs exist in LMIC institutions, proposals for research training hubs and networks within countries and/or regions are encouraged. The Need for a Multidisciplinary Approach: Risk factors for NCDs are complex and differentially amenable to control.

Environmental influences, trauma, infection, lifestyle factors, diverse socio-economic influences and epigenetic changes interact with underlying genetic vulnerability to influence the trajectory and severity of many NCDs. Increasing evidence for the prenatal and childhood roots of chronic NCDs provide possible avenues for early prevention of and intervention for NCDs.

During the past several decades, improvements in health care have led to a decrease in child mortality and an increase in life expectancy in LMICs. However, many of the factors that previously contributed to early mortality remain and influence later health outcomes.

These positive trends have, therefore, set the stage for a complex epidemiology of health and disease as more children survive into adulthood predisposed by early disease, malnutrition and adverse environmental and psychological influences and experiences to later development of chronic diseases such as cardiovascular and cerebrovascular disease, diabetes, cancer, mental illness, substance abuse, developmental, neurological and neurodegenerative diseases and disorders.

During the remainder of the lifecycle, social and environmental factors such as environmental pollutants and chronic stress continue to influence health. However, individual behaviors and exposures such as physical inactivity, poor diet, tobacco, alcohol and drug abuse become increasingly important risk factors influencing the trajectory of NCDs.

It is critical to develop a deeper understanding of the complex motivations that contribute to decision making and risky behavior in resource poor settings.

The factors that are responsible for onset and prevention of chronic disease are complex, so trainees must gain a broad appreciation for the need for research across health disciplines that may encompass genetics, medicine, nutrition, psychology, behavioral health, epidemiology, population studies, health law, environmental health, and public health, as well as many disciplines not traditionally associated with health research such as business administration, economics, urban planning, information science, communications, organizational and management theory, finance, individual and systems-level behavioral change, statistics, anthropology, learning theory, and marketing.

While no one trainee can acquire expertise in all these fields, training might include development of team projects that include trainees from multiple fields of expertise and provide experience in collaborative interdisciplinary team research. In the context of this FOA, "trainees" are individuals from the host/target LMIC(s) eligible for research training under this FOA and according to the applicant's proposed selection criteria.

The proposed training is expected to strengthen sustainable research and research training capacity at the LMIC institution. The program application should incorporate an appropriate mix of long-, medium- and short-term training opportunities and in-country mentored research to address the research training needs for NCDs identified for the LMIC.

Applicants are encouraged to design multi- and inter-disciplinary research training programs and teams. Training can take place in the U.S. or LMIC, with the goal for most of the training to occur within the LMIC by the end of the initial grant award period.

Applications involving already existing research training collaborations under other programs at the same LMIC sites are expected to begin with a substantial level of research training within the LMIC that takes advantage of the research training infrastructure already created (such as faculty and courses). Training-related research should always be carried out in the LMIC.

In addition to early career short-, medium- and long-term training, mid-career training is also allowed. The actual training mix should be justified according to the assessed needs and already existing infrastructure and the level of research capacity and training infrastructure in the LMIC.

In LMICs with weak research infrastructure and where few established NCD-related researchers and potential faculty exist to support an institutional research training program, more degree-related research training in the U.S. may be necessary to develop the initial cadre of researchers who can then go on to be mentors and faculty in the LMIC for future trainees.

In LMICs where substantial research and training infrastructure and expertise already exist, but without a strong focus on NCDs, a mix of NCD-oriented activities that augment existing research, training and personnel resources at the LMIC institution(s) may be proposed.

The LMIC activities would enhance their individual and institutional capacity to identify, undertake and successfully complete NCD studies and to utilize the results from research that they and others conduct to influence teaching, implementation and country policy.

While innovative research training models for NCDs are encouraged, typically research training programs involve the following: Long-term (master's or doctoral degree and other training that is six months or longer) training for the full range of skills necessary to plan, conduct, manage and disseminate the results of research on NCDs with the understanding that the focus of thesis and training-related research will be in the LMIC.

Advanced degree or non-degree research training may be supported at a U.S. or foreign institution. Research trainees who are also training as clinicians must devote their time to the proposed research training and must confine clinical duties to those that are an integral part of the research training experience.

Medium-term (three- to up to six-months) training or mentoring, which may include specialized research, policy or administrative/business skills necessary to conduct research that is planned or ongoing and translate results for interventions and policy.

Short-term (less than three months) training or mentoring that focuses on research skills and methodology, laboratory skills necessary to support research, ethics and compliance issues, grant writing, peer review, preparation of scientific manuscripts, data management, technology transfer, medical informatics, and other relevant areas. Additional institutional capacity-building efforts are encouraged.

These may include, but are not limited to, in-country training workshops in advanced techniques; distance learning; and interaction with other national and regional efforts to strengthen the ability of institutions to identify and undertake successful research and research training in NCDs to influence teaching, implementation and country policy.

Proposed research training can take place in the U.S. or a foreign country, but training-related research should be carried out in the LMIC. Scientific research training for clinicians and healthcare professionals including physicians, nurses, dentists, social work professionals and other practitioners is encouraged.

It is expected that LMIC trainees will disseminate the results of their research at scientific conferences and in peer-reviewed publications. Advanced in-country mentored research may be undertaken by the trainee in his/her home country upon completion of his/her initial period of long-term training under the program (Master's, Ph. D.

, post-doctoral or other long-term training) and may be supported by the training program .

All training-related research projects in which trainees are involved under this award must be independently peer-reviewed through scientific review procedures established by the applicant institution, and have written evidence of documentation of education in the protection of human subjects for the trainee, compliance with the required federal citations, and approval from an institutional (or ethical) review board or committee at the applicant institution and, if different, at the LMIC institution in which the research is being conducted.

Where appropriate, the design of training-related research projects should account for potential sex and gender differences that may affect the questions asked and the analyses performed. These might include different responses to and impacts of health interventions, differences in physiology, and different behavioral bases for disease prevention strategies.

This NCD-LIFESPAN program strongly encourages principal investigator/program directors (PIs/PDs) to include women, and individuals from groups underrepresented in biomedical and behavioral research in the country (including individuals from racial, ethnic and socially disadvantaged backgrounds and those living with disabilities), as faculty and research trainees at all sites.

Specific Interests of the FOA Sponsors NIH institutes and Centers (ICs) participating in this announcement will consider applications for funding. Because of the differences in individual Institute and Center (IC) program interests for this FOA, prospective applicants should carefully note which ICs participate in this announcement and view their respective areas of research interest and requirements below.

Applicants can obtain additional information and research interests for each of the FOA's sponsoring partners at their websites and by contacting the partner program official listed in this announcement (Section VII. Agency Contacts). The National Institute of Neurological Disorders and Stroke ( NINDS , www.

ninds. nih. gov ) is interested in supporting innovative research training programs for basic, mechanistic, epidemiological, prevention, translational and clinical research across the spectrum of neurological, neuromuscular and neurovascular diseases and disorders.

In addition to prevalent neurological disorders and stroke, NINDS is also interested in supporting research in areas of rare and neglected neurological diseases that are relevant to low- and middle- income countries (NINDS Disorder Index http://www. ninds. nih.

gov/disorders/disorder_index. htm ). The NINDS strongly encourages training in scientific rigor and experimental design.

Trainees should have a thorough understanding of the principles and practices of rigorous scientific research. These principles should be examined in the context of the collection, appropriate analysis and interpretation of scientific data. Programs are also encouraged to provide education in human decision-making tendencies and cognitive biases, and how they can lead to erroneous interpretation of data (c.

f. Kahneman, D. 2011 Thinking, Fast and Slow.

New York. Farrar, Straus and Giroux). Programs are expected to provide formal instruction in the principles of rigorous experimental design to ensure that trainees understand the practices required for robust hypothesis testing and the application of these principles and practices to their individual research (see: NINDS Rigor Resources : https://www.

ninds. nih. gov/Current-Research/Trans-Agency-Activities/Rigor-Transparency/RigorChampionsAndResources ).

The National Center for Complementary and Integrative Health (NCCIH) is interested in supporting training programs investigating the use of complementary approaches for Chronic, Non-Communicable Diseases and Disorders, for which these approaches are most frequently used.

These would include, but not be limited to, investigations of the impact of complementary health modalities in alleviating chronic pain syndromes and inflammatory processes, and improving health and wellness. Complementary health approaches of interest to NCCIH include both mind-body and natural product approaches.

Training programs can propose secondary data analyses, non-interventional, observational, or epidemiological clinical research, or basic mechanistic and non-clinical translational research. NCCIH will not support training programs proposing interventional clinical trial research through this FOA. Applicants are strongly encouraged to contact NCCIH program staff prior to submission.

chart the course of neuropsychiatric disorders over the lifespan in order to understand ideal times and methods for intervention to prevent, preempt progression of, or treat mental disorders and hasten recovery; describe the molecules, cells, and circuits associated with typical and atypical behavior; identify genomic, epigenomic, and other factors such as the environment and experience across diverse populations that are associated with mental illnesses; Identify clinically useful biomarkers and behavioral indicators that predict change across the trajectory of illness examine the interactions of neurobiological and environmental/social factors that affect brain development, resulting in behavioral outcomes (e.g. expression of cognitive impairment, coping, adaptation, response to interventions) ; conduct psychosocial and biomedical intervention trials that identify and test the mechanisms, moderators, and predictors (e.g. biological, genetic, behavioral, experiential, environmental) of intervention response and side effects in different patient populations; develop new preventive and treatment interventions based on discoveries in genomics, neuroscience, and behavioral science; develop innovative approaches for the delivery of psychosocial and biomedical interventions by different kinds of providers and within different service settings; develop and test models and methods for implementing mental health interventions: 1) in diverse systems of health care; and 2) to meet the needs of groups with inadequate access to evidence-based mental health services (e.g. based on age, sex, gender, stage of illness, race/ethnicity, rural or urban setting, or other factors); improve the efficiency and effectiveness of existing mental health services; and develop innovative service delivery models to optimize the outcomes of mental health services received in diverse communities and populations The National Institute on Alcohol Abuse and Alcoholism (NIAAA) fosters international collaboration in research and research training that advances the understanding of alcohol misuse and alcohol use disorder (AUD).

This includes research on prevention of alcohol misuse of alcohol and alcohol use disorder, improving the health and well-being of individuals living with AUD and alcohol-associated pathology , such as fetal alcohol spectrum disorders (FASD) and organ damage, and reducing alcohol-related morbidity and mortality.

Specifically, NIAAA supports international research that provides a unique opportunity to generate and disseminate fundamental knowledge on the effects of alcohol misuse on health and applies that knowledge for finding solutions to improve prevention and treatment of alcohol misuse and alcohol use disorder across the lifespan.

NIAAA encourages research training that capitalizes on emerging research opportunities and provides trainees with knowledge and advanced skills in areas that include, but are not limited to, the following: genetic, epigenetic, neurobiological, and behavioral mechanisms and interactions of individual and environmental factors that affect prevention, disease progression, and recovery in alcohol use disorder and alcohol-associated pathology across the lifespan, biomarkers and indicators that predict disease progression and response to interventions, translation of scientific discoveries to new interventions, novel approaches to prevention and treatment of alcohol misuse, alcohol use disorder, and related conditions, therapeutic approaches, medications, and other treatments to mitigate alcohol-associated deficits and disorders, such as alcohol-associated liver disease, across the lifespan, and innovation in identification and service delivery models to optimize the outcomes in diverse communities and populations.

Research shows that diverse teams working together outperform homogenous teams. Scientists and trainees from diverse backgrounds and with different life experiences bring different perspectives, creativity, and individual enterprise to address complex scientific problems. Diverse teams of scientists will lead the way to develop more innovative inclusive research that will more broadly enhance public health.

Fostering diversity by addressing underrepresentation in the scientific research workforce is a key component of the NIH strategy to identify, develop, support, and maintain the quality of our scientific workforce. It is expected that the research programs will include a diverse group of scientists, including individuals from underrepresented backgrounds as per NOT OD 20-031 (Notice of NIH's Interest in Diversity).

NIAAA is especially interested in enhancing representation from racial, ethnic and gender minorities and early-stage investigators. This program does not support applications primarily focused on cancer if submitted from U.S. institutions and otherwise eligible under the NCI D43 program at: https://grants. nih.

gov/grants/guide/rfa-files/RFA-CA-20-031. html "Strengthening Institutional Capacity to Conduct Global Cancer Research in Low- and Middle-Income Countries", D43 (direct foreign applications are not currently eligible for RFA-CA-20-031 ). This program will continue to support Cancer-related D43 applications directly from LMIC institutions (with or without a U.S. partner).

This program does not support Trauma and Injury related Research Training that is otherwise eligible under: Fogarty Global Trauma and Injury Research Training Program (D43 Clinical Trial Optional) (RFA-TW-21-003, https://grants. nih. gov/grants/guide/rfa-files/RFA-TW-21-003.

html ). Please see the FOAs and discuss with the listed program contacts if you have any questions.

Note : This Funding Opportunity Announcement (FOA) allows appointment of Trainees (D43) proposing to serve as the lead investigator of an independent clinical trial; or proposing a separate ancillary clinical trial; or proposing to gain research experience in a clinical trial led by another investigator, as part of their research and career development. See Section VIII. Other Information for award authorities and regulations.

Section II. Award Information Grant: A support mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity. Application Types Allowed The OER Glossary and the SF424 (R&R) Application Guide provide details on these application types.

Only those application types listed here are allowed for this FOA. Optional: Accepting applications that either propose or do not propose clinical trial(s). Need help determining whether you are doing a clinical trial?

Funds Available and Anticipated Number of Awards Application budgets are limited to $230,000 per year for new awards and $250,000 per year for renewal awards (total direct costs). The maximum project period is up to 5 years. Other Award Budget Information Stipends, Tuition, and Fees Stipends: Awards may provide stipends as a subsistence allowance to help defray living expenses during the research training experience.

Trainees may be paid a stipend comparable to their professional experience. Tuition and Fees: Funds for tuition and academic fees at the U.S. or foreign institution may be requested. However, programs are encouraged to seek cost-sharing arrangements with the grantee institutions to provide reduced tuition for trainees.

Note that health insurance is not included as part of this budget category and is now included under Training Related Expenses category. Tuition and fees are excluded from the F&A base. Health insurance is included in the F&A base.

Trainee Travel: Trainee travel to participate in training experiences at other institutions or to present their research results at scientific meetings that the institution determines to be necessary for the individual's research training experience is an allowable trainee expense.

Training Related Expenses Training related expenses: Awards will provide funds to help defray other research training expenses, such as health insurance, training equipment (not exceeding $5000), trainee research supplies, laptop computers and internet access, relevant journal subscriptions and publication costs and costs for short courses or workshops.

One-time advanced in-country research training support of up to $20,000 direct costs may be included for mentored research to be undertaken by a long-term trainee in his/her country.

Other Program Related Expenses Limited program-related administrative and clerical salary costs associated distinctly with the program that are not normally provided by the applicant organization may be direct charges to the grant only when they are in accordance with applicable cost principles. This type of training program may qualify as a "major project" where administrative salaries are allowable as a direct cost.

When specifically identified and justified, these expenses must be itemized in Sections A and B, as appropriate, of the R&R Budget. Faculty: Salary for the PD(s)/PI(s), other key personnel, training faculty and administrative staff may be requested at levels commensurate with the salary structure and benefits at the institution where they are employed and within the limits described at http://grants. nih.

gov/grants/policy/salcap_summary. htm . Collaborators may receive appropriate compensation for their significant activities on the program, such as recruitment and selection activities, as well as other program-related roles.

The administrative, training or teaching responsibilities and time commitment for personnel receiving salary should be thoroughly described. The salary and fringe benefits for the faculty and staff should not exceed 25 percent of total direct costs.

Funds may be requested for round-trip economy airfare on U.S. carriers (to the maximum extent possible) and lodging and per diem for the PD/PI(s) and faculty to attend the annual program networking meeting, normally in the U.S. Funds for one trip per year may be requested for faculty mentors to conduct well justified training activities.

Support for key personnel, faculty mentors or consultants to attend scientific meetings and conferences is not allowed. These expenses must be justified as specifically required by the proposed program and must not duplicate items generally available at the applicant institution.

Indirect Costs (also known as Facilities & Administrative [F&A] Costs) are reimbursed at 8% of modified total direct costs (exclusive of tuition and fees, consortium costs in excess of $25,000, and expenditures for equipment), rather than on the basis of a negotiated rate agreement. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this FOA. Section III.

Eligibility Information Higher Education Institutions Public/State Controlled Institutions of Higher Education Private Institutions of Higher Education The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education: Hispanic-serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISIs) Nonprofits Other Than Institutions of Higher Education Nonprofits with 501(c)(3) IRS Status (Other than Institutions of