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Find similar grantsControlling Cellular Machinery - Diagnostics and Therapeutics is sponsored by DARPA Defense Sciences Office. DARPA is soliciting research proposals for the development of synthetic regulatory genetic elements that can be used in mammalian cells to detect, treat, or prevent disease.
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gov Maintenance Calendar Controlling Cellular Machinery - Diagnostics and Therapeutics DARPA - Defense Sciences Office Document Type:Grants Notice Funding Opportunity Number:DARPA-BAA-11-23 Funding Opportunity Title:Controlling Cellular Machinery - Diagnostics and Therapeutics Opportunity Category:Discretionary Opportunity Category Explanation: Funding Instrument Type:Cooperative Agreement Procurement Contract Category of Funding Activity:Science and Technology and other Research and Development Expected Number of Awards: Assistance Listings:12.
910 -- Research and Technology Development Cost Sharing or Matching Requirement:No Original Closing Date for Applications:Mar 03, 2011 Current Closing Date for Applications:Mar 03, 2011 Archive Date:May 03, 2011 Estimated Total Program Funding: Eligible Applicants:Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility" Additional Information on Eligibility: ## Additional Information Agency Name:DARPA - Defense Sciences Office Description:DARPA is soliciting research proposals for the development of synthetic regulatory genetic elements that can be used in mammalian cells.
The proposed research should comprise approaches that enable fundamental advances to the development and broad application of synthetic regulatory elements for in vivo biomedical applications to detect, treat, or prevent disease.
Technical challenges that need to be addressed include, but are not limited to, discovery, characterization, evolution or design, and demonstration of orthogonal and modular genetic regulatory elements; construct stability and function in the cell; and synthesis, amplification, and delivery of novel circuits in mammalian cells.
The designed modules must limit specific interactions with the cellular metabolism or milieu to the desired performance characteristics and demonstrate maintenance of independent function without interference long enough to achieve the intended clinical effect. Specifically excluded is research that primarily results in evolutionary improvements to the existing state of practice.
Proposers that intend to pursue nucleic acid vaccines as an application are referred to the companion announcement, Controlling Cellular Machinery - Vaccines, DARPA-BAA-11-22. Link to Additional Information:[](https://www. grants.
gov/search-results-detail/58910) Grantor Contact Information:If you have difficulty accessing the full announcement electronically, please contact: #### Health & Human Services * Frequently Asked Questions ## Your session will expire in 3 minutes. To continue working, click on the "OK" button below. This is being done to protect your privacy.
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According to the current listing, eligibility includes: Unrestricted (i. e. , open to any type of entity), subject to any clarification in text field entitled 'Additional Information on Eligibility'. Confirm the full requirements in the official notice before applying.
Controlling Cellular Machinery - Diagnostics and Therapeutics is funded by DARPA Defense Sciences Office. Verify program details on the funder's official page before applying.
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