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Core Biological Sciences Research is sponsored by U.S. National Science Foundation, Directorate for Biological Sciences (BIO). The NSF BIO supports foundational research across all areas of biology, advancing fundamental understanding of the dynamics, functions, and interactions of biological systems at all scales of organization, ranging from molecules to organisms to ecosystems.
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Directorate for Biological Sciences (BIO) | NSF - U.S. National Science Foundation Directorate for Biological Sciences (BIO) View image credit & caption Directorate for Biological Sciences (BIO) The U.S. National Science Foundation Directorate for Biological Sciences (NSF BIO) supports research and education that advances the understanding of all forms of life and their components at all scales — from molecules to ecosystems and across space and time.
New NSF-supported center will accelerate data-driven understanding of organismal resilience and adaptation BIO Newsletter: August 2026 Core Research in Biological Sciences (BIO Core) Next Required Due Date: Proposals Accepted Anytime Unleashing a new age of AI-enabled scientific discovery through the Genesis Mission Next Required Due Date: See letter for details Unlocking Dataset Value for AI-Enabled Scientific Discovery (AI Datasets) Next Required Due Date: November 4, 2026 Postdoctoral Research Fellowships in Biology (PRFB) Next Required Due Date: September 29, 2026 NSF Graduate Research Fellowship Program (GRFP) Next Required Due Date: October 19, 2026 Advancing Research at the intersection of Biology and Artificial Intelligence/Machine Learning (AI/ML) Next Required Due Date: See letter for details View all BIO opportunities Core biological sciences research Advancing fundamental understanding of biological systems at all scales of organization, ranging from molecules to organisms to ecosystems.
Funding development of the biological sciences workforce through education and training at multiple career stages. Additional initiatives and infrastructure Supporting research and partnerships to advance biological discovery and infrastructure capacity. Thursday, October 15, 2026, 1:00 p.
m. – 2:00 p. m.
NSF BIO Virtual Office Hour Webinar: Updates from the NSF Directorate for Biological Sciences Q&As and information sessions Please join the U.S. National Science Foundation Directorate for Biological Sciences for a directorate-wide virtual office hour. Wednesday, November 18, 2026, 1:00 p. m.
– 2:00 p. m. NSF BIO Virtual Office Hour Webinar: Updates from the NSF Directorate for Biological Sciences Q&As and information sessions Please join the U.S. National Science Foundation Directorate for Biological Sciences for a directorate-wide virtual office hour.
NSF launches three new Science and Technology Centers with $90M investment in transformative research Eight NSF research institutes to propel U.S. quantum science with $290M investment NSF announces $1. 5B for foundational research to drive scientific breakthroughs for American technological leadership
According to the current listing, eligibility includes: U. S. scientists, engineers, and educators from across the country can submit proposals for research and education. Confirm the full requirements in the official notice before applying.
Core Biological Sciences Research is funded by U.S. National Science Foundation, Directorate for Biological Sciences (BIO). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Addressing separation and purification challenges in biorefineries is sponsored by European Commission — Horizon Europe. Expected Outcome: Successful proposals will contribute to the updated EU Bioeconomy Strategy, the Circular Economy Act, the Clean Industrial Deal, the European Chemical Industry Action Plan and the Chemicals Strategy for Sustainability. Projects results are expected to contribute to the following expected outcomes: Enhancing competitiveness, efficiency, sustainability, circularity and safety of industrial biorefineries. Efficient, selective and scalable separation and purification technology platform(s) with high potential to be integrated within existing and/or new biorefineries. Purity and stability of targeted intermediates/product(s) compatible with further conversion requirements. Scope: While significant advancements have been made in recent years in the development of core biorefinery processes, challenges remain in separation and purification steps. Separation and purification, both upstream and downstream of biorefinery processes, play a key role in determining quality and purity of the intermediates and products. They usually account for a significant share of the whole process costs and are often a relevant bottleneck towards full-scale deployment and commercialisation of bio-based products (including intermediates, chemicals, ingredients, materials). It is therefore crucial to develop new technologies to improve separation and purification performances, while at the same time improving resource efficiency and reducing costs. Proposals under this topic should: Develop scalable separation and purification technologies and test the developed innovative solutions on at least 3 use cases from biorefinery processes at industrial or demo scale. Each technology should address at least two of the following: increase efficiency when using available green solvents (including water), or develop novel ones and in both cases minimise the use of harsh solvents; applying process intensification including through reduction of process steps; reducing thermal and/or electric energy and water consumption. Address compatibility of the innovative separation and purification solutions with existing upstream technologies or develop solutions that address simultaneously the upstream and downstream challenges. Test and validate the performance of targeted technologies and their effect on selected bio-based product(s). Both novel (not yet available on the market) and well-established bio-based products are in scope. In addition to the specific requirements applicable for the type of action, as described in section 2.2.3.1 of the CBE JU Annual Work Programme 2026 [1] , proposals under this topic should: Include a task to apply the SSbD framework, developed by the European Commission for the assessment of targeted biorefinery products obtained using the developed separation and purification processes. For more information on the SSbD framework and criteria, refer to Safe and sustainable by design . Ensure complementarities with past and ongoing R&I projects addressing similar challenges, including projects funded under Horizon 2020/Horizon Europe (under Cluster 6 and other Clusters of Horizon Europe) and BBI JU/CBE JU projects. [1] https://www.cbe.europa.eu/reference-documents Programme areas: Global Challenges and European Industrial Competitiveness, Food, Bioeconomy Natural Resources, Agriculture and Environment, Bio-based Innovation Systems in the EU Bioeconomy, Horizon Europe (HORIZON) Keywords: Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation, Industrial biotechnology, bio-based products, biorefineries, downstream, green solvents, purification technologies, resource efficiency, safe and sustainable by design, separation technologies
The FY 2026 Continuation of Solicitation for the Office of Science Financial Assistance Program is an open annual grant from the U.S. Department of Energy (DOE) Office of Science that funds research across its core program areas, including Advanced Scientific Computing Research, Basic Energy Sciences, Biological and Environmental Research, Fusion Energy Sciences, High Energy Physics, Nuclear Physics, and Isotope R&D and Production. Any research within SC's Congressionally authorized mission may be proposed under this solicitation, which remains open throughout the fiscal year. Eligible applicants include colleges and universities, non-profit and for-profit research organizations, DOE national laboratories, small businesses, and other federal research organizations. Anticipated awards range from $750,000 to $3,000,000 per year; the solicitation closes September 30, 2026.
NSF 26-517 replaces the core solicitations of Environmental Biology, Integrative Organismal Systems and Molecular and Cellular Biosciences with a single directorate-wide opportunity. Proposals are accepted anytime, sorted centrally by NSF rather than targeted by the PI, and reorganized under three inquiry areas. Here is what the $280 million actually buys, why the loss of program targeting cuts both ways, and what to do before the September 16 webinar.
Read articleNSF's Arctic Research Opportunities solicitation funds roughly 75 awards a year — up to $50 million — across six program areas from natural sciences to social sciences to the Arctic Observing Network. The July 15, 2026 target date is not a hard deadline, and understanding that distinction is the first strategic decision an Arctic researcher makes. Here is how the six doors differ and how to choose the right one.
Read articleAwards slashed by half, life sciences applicants rejected at 95%, and the White House steering which fields get funded. How the GRFP went from funding the person to funding the priority.
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