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Find similar grantsCurrent NCI SBIR Contract Solicitation PHS 2025-1 is sponsored by National Cancer Institute (NCI). This solicitation outlines specific contract topics for small businesses to propose research and development projects related to cancer prevention, detection, diagnosis, treatment, and basic research.
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Current NCI SBIR Contract Solicitation - NCI Current NCI SBIR Contract Solicitation Program Solicitation PHS 2025-1 The application period is closed [ View solicitation ]. FY25 NCI SBIR Contract Solicitation Webinar [ View recording ] Below were the 13 topics included in the PHS 2025-1 SBIR Contract Solicitation.
NIH/NCI 466 - Novel Delivery Systems for RNA-based Cancer Vaccines NIH/NCI 467 - Development of Cancer Immunoprevention Agents NIH/NCI 468 - Synthetic Microbes (Excluding Oncolytic Viruses) for Immuno-Oncology Therapies NIH/NCI 469 - Development of Novel Therapeutics for HPV-related Precancer NIH/NCI 470 - Precision Nutrition Interventions to Reduce Cancer-Related Symptoms NIH/NCI 471 - Drug-Loaded Carrier Particles for Improved Oral Delivery for Colon Cancer Prevention NIH/NCI 472 - Antibody-Drug Conjugates as Radiopharmaceutical Theranostics for Cancer NIH/NCI 473 - Point of Care Detection of Antibodies Against HPV16/18 E6 and E7 Oncoproteins in Oropharyngeal Cancer NIH/NCI 474 - Point of Care Technologies for GI Cancer Prevention and Early Detection NIH/NCI 475 - Development of Digital Biomarkers and Endpoints for Clinical Cancer Care NIH/NCI 476 - Digital Twin Software for Optimization of Cancer Radiation Therapy NIH/NCI 477 - Wearable Technologies to Facilitate Remote Monitoring of Cancer Patients Following Treatment NIH/NCI 478 - Advanced Biomaterials to Improve Cancer Modeling for Research For additional information, please see the NCI Board of Scientific Advisors (BSA) presentation on the PHS 2025-1 SBIR Contract Solicitation topics.
Applicants must use the Contract Proposal Submission (eCPS) website to submit their proposal. No other method of proposal submission is permitted. Instructions for electronic submission are provided in the solicitation.
Actual contract topic numbers will be available in the solicitation. For more information, contact Tanya Renwick, contract analyst in the Office of Acquisitions, at ncioasbir@mail. nih.
gov .
According to the current listing, eligibility includes: Small businesses with research capabilities and technological expertise to contribute to the research and development missions of the NCI. Confirm the full requirements in the official notice before applying.
Current NCI SBIR Contract Solicitation PHS 2025-1 is funded by National Cancer Institute (NCI). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
On May 21, 2026, the National Cancer Institute posted RFA-CA-27-006, RFA-CA-27-007, and RFA-CA-27-008 — the three competitive renewals for the NCI Community Oncology Research Program. Combined FY 2027 commitments reach $147.5 million across roughly 57 awards: $74.5 million for up to 7 Research Bases, $73 million for up to 50 Community and Academic Community Sites. Pre-application webinars run June 16-18 this week. Applications are due August 18, 2026 with six-year project periods. For community hospitals, oncology consortia, and NCI-designated cancer centers, this is the single largest cancer clinical-trials infrastructure decision NCI makes until 2033.
Read articleThe Breast Cancer Research Foundation launched a $100 million venture philanthropy fund at CGI on September 22, 2026, seeded with $23 million and aiming at 20 to 30 companies. Here is what the structure actually means for investigators, for startups in the valley of death, and for every disease foundation now weighing the same move.
Read articlePAR-27-062 creates a three-year, $80,000-salary postdoctoral career award across NCI, NIAID, NIBIB, NIDCR and NINDS — and it carries a hard eligibility window that closes two years after you start your postdoc. Full analysis of the Academic Career Excellence Award, what it replaces, and why the timing rule is the whole competition.
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