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Program 24-505 has been archived. The page directs users to the latest version at PD 26-8011.
Designing Synthetic Cells Beyond the Bounds of Evolution (Designer Cells) is sponsored by National Science Foundation (NSF). This solicitation supports research that develops cell-like systems to identify minimal requirements for life, designs synthetically-modified cells to address fundamental questions in evolution or explore biological diversity, and leverages basic research in cell design to build…
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Designing Synthetic Cells Beyond the Bounds of Evolution (Designer Cells) | NSF - U.S. National Science Foundation Designing Synthetic Cells Beyond the Bounds of Evolution (Designer Cells) Archived funding opportunity This document has been archived. See PD 26-8011 for the latest version.
NSF's implementation of the revised 2 CFR NSF Financial Assistance awards (grants and cooperative agreements) made on or after October 1, 2024, will be subject to the applicable set of award conditions, dated October 1, 2024, available on the NSF website . These terms and conditions are consistent with the revised guidance specified in the OMB Guidance for Federal Financial Assistance published in the Federal Register on April 22, 2024.
Important information for proposers All proposals must be submitted in accordance with the requirements specified in this funding opportunity and in the NSF Proposal & Award Policies & Procedures Guide (PAPPG) that is in effect for the relevant due date to which the proposal is being submitted. It is the responsibility of the proposer to ensure that the proposal meets these requirements.
Submitting a proposal prior to a specified deadline does not negate this requirement.
Updates to NSF Research Security Policies On July 10, 2025, NSF issued an Important Notice providing updates to the agency's research security policies, including a research security training requirement, Malign Foreign Talent Recruitment Program annual certification requirement, prohibition on Confucius institutes and an updated FFDR reporting and submission timeline.
Supports research that designs and builds synthetic or artificial cells or cell-like systems to explore questions about biological function or evolution of life processes, as well as for biotechnology applications. Because of recent technological advances in synthetic biology and bioengineering, researchers are now able to tailor cells and cell-like systems for a variety of basic and applied research purposes.
The goal of this solicitation is to support research that (1) develops cell-like systems to identify the minimal requirements for the processes of life, (2) designs synthetically-modified cells to address fundamental questions in the evolution of life or to explore biological diversity beyond that which currently exists in nature, and (3) leverages basic research in cell design to build novel synthetic cell-like systems and cells for innovative biotechnology applications.
Highest funding priority is given to proposals that have outstanding intellectual merit and broader impacts, while proposals with weaknesses in either category (or those that are perceived as likely to have an incremental impact) will not be competitive.
Proposals submitted to this solicitation should address social, ethical, and safety issues associated with designing and building synthetically modified cells as an integrated component of the project.
Awards made through this program Browse projects funded by this program Map of recent awards made through this program Directorate for Biological Sciences (BIO) Division of Molecular and Cellular Biosciences (BIO/MCB) Directorate for Engineering (ENG) Division of Chemical, Bioengineering, Environmental and Transport Systems (ENG/CBET) Directorate for Social, Behavioral and Economic Sciences (SBE) Division of Social and Economic Sciences (SBE/SES)
Key questions and narrative sections extracted from the solicitation.
Describe cell-like systems identifying minimal requirements for life processes
Describe synthetically-modified cells addressing fundamental evolutionary questions or exploring non-natural biological diversity
Describe novel synthetic systems leveraging cell design for biotechnology applications
Integrate social, ethical, and safety issues as an essential component of the proposed project
Scoring criteria used to review proposals for this grant.
According to the current listing, eligibility includes: Non-profit, non-academic organizations; independent museums, observatories, research laboratories, professional societies, and similar U. S. Confirm the full requirements in the official notice before applying.
Designing Synthetic Cells Beyond the Bounds of Evolution (Designer Cells) is funded by National Science Foundation (NSF). Verify program details on the funder's official page before applying.
Yes — this listing is flagged as national in scope, so applicants across the U.S. may apply, subject to the sponsor's other eligibility criteria.
Applications go through the funder's official portal — the Apply Now link on this page goes there directly.
MGPV Travel Grant is sponsored by Geological Society of America (GSA), Mineralogy, Geochemistry, Petrology, Volcanology Division. MGPV Travel grants support student travel to the annual GSA meeting. Applications are restricted to active graduate or undergraduate students who are the presenting authors of an accepted abstract at the annual GSA meeting.
Research Opportunities in Space and Earth Science (ROSES) - 2025: A.4 Rapid Response and Novel Research in Earth Science is sponsored by National Aeronautics and Space Administration (NASA) Science Mission Directorate (SMD). This omnibus research funding opportunity includes various program elements, with rolling submissions for Earth Science research through August 2026. Proposers to Earth Science using the NASA Center for Climate Simulation high-end computing facility must include specific budget details.
TCUP lists eight funding tracks and roughly $10.3M a year, but the October 14, 2026 deadline applies to only three of them — CHAI, Pre-TI, and TCUP Partnerships — and each carries a restriction that disqualifies most applicants. Here is the track-by-track math.
Read articleNSF 26-513 makes roughly $100 million available for up to 10 State and Regional AI Infrastructure Hubs at $4M to $12M each over five years. One award per state or multi-state region. One proposal per organization. And NSF is not buying you GPUs — it funds the coordination, the workforce and the faculty training, while the compute has to come from partners you have to already have.
Read articleAs of September 12, NSF had obligated $6.3 billion across 6,200 grants versus $8.1 billion and 8,600 last year. AHRQ has made 61 awards. Judge Allison Burroughs ordered the government to report by September 28 on whether IES will obligate $180 million before it expires. Here is what actually happens to the money on October 1 — and what it means for your FY2027 application.
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