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Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R61/R33 Clinical Trial Required) is sponsored by National Institute of Mental Health (NIMH), National Institutes of Health (NIH). This funding opportunity supports early-stage, clinically grounded research to create and refine new psychosocial interventions and prevention strategies for mental disorders, with a required clinical trial component.
It emphasizes an experimental therapeutics approach, focusing on clearly defined intervention targets and demonstrating target engagement in relation to clinical outcomes. The R61 phase provides up to two years for preliminary testing of target engagement, and the R33 phase provides up to three additional years to replicate target engagement and test its association with changes in clinical outcomes.
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Or search similar grants →According to the current listing, eligibility includes: Eligible applicants include public and private institutions of higher education, nonprofits, small businesses, for-profit organizations, and various government entities. Foreign organizations are also eligible. Confirm the full requirements in the official notice before applying.
The current listing shows no budget cap; project period up to 3 years. Total NIMH commitment (all related NOFOs): $27M in FY 2026. Verify award ceilings, matching requirements, and allowable costs in the official notice.
Applications for Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R61/R33 Clinical Trial Required) are due October 15, 2027. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R61/R33 Clinical Trial Required) is funded by National Institute of Mental Health (NIMH), National Institutes of Health (NIH). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Past winners and funding trends for this program
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