Diabetes and Metabolism HIV/AIDS Program

Diabetes and Metabolism HIV/AIDS Program is sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). This opportunity supports mission-aligned projects and measurable outcomes.

Diabetes & Metabolism HIV/AIDS - NIDDK NIH Websites Are Changing Research Programs & Contacts Diabetes & Metabolism HIV/AIDS Diabetes & Metabolism HIV/AIDS Studies on the metabolic complications of HIV infection and treatment, including endocrine and body composition abnormalities.

The Diabetes and Metabolism HIV/AIDS program supports innovative basic science and clinical research on the role of HIV infection, including relevant host conditions, or antiretroviral therapy (ART) on metabolic and endocrine dysfunction.

Specific areas of support include, but are not limited to: Studies to elucidate the mechanisms underlying the effects of HIV and/or ART on metabolism (including glucose, lipid, and skeletal metabolism), body composition, and general endocrine function through basic and clinical research Studies that elucidate novel approaches to prevent or manage diabetes and/or other endocrine disorders in HIV-infected individuals.

However, such studies should target pathways unique to the development of these disorders in the context of HIV infection and/or its treatment rather than simply testing treatments accepted in non-HIV-infected individuals Studies that elucidate the interactions between HIV, ART, and/or HIV-associated inflammation and diabetes-related medications to provide a basis for individualized therapy Studies that determine the extent to which HIV and its therapy increase the risk of diabetes and/or other endocrine or metabolic dysfunction and identify factors which augment or ameliorate the risk Studies that discover and validate biomarkers for metabolic and/or endocrine disease progression as a result of HIV infection or its treatment Studies that employ non-invasive or minimally invasive means to assess tissue-specific or whole body metabolic changes in vivo due to HIV infection or therapy Animal studies will not be considered except for those in non-human primates.

Minnjuan Flournoy Floyd, Ph. D. , M.

P. H. , M.

B. A. Adult T2D research; clinical and public health research in T2D and HIV/AIDS Saul Malozowski, M.

D. , Ph. D.

, M. B. A.

Neuroendocrinology of hypothalamic-pituitary axis, neuropeptide signaling and receptors; hormonal regulation of bone and mineral metabolism; HIV/AIDS-associated metabolic and endocrine dysfunction HIV/AIDS comorbidities, complications, coinfections O’Brien Kidney & Urologic Disease Centers; Kidney HIV/AIDS; Clinical Translational Studies NIDDK Grant Opportunities Highlighted Topics of Interest to NIDDK NIDDK Active Trials in Diabetes and Endocrine Disease View related clinical trials from ClinicalTrials.

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Learn about Human Subjects Research Learn about NIDDK Translational Research Opportunities Diabetes Mellitus Interagency Collaborating Committee (DMICC) Type 1 Diabetes and Cardiorenal Outcomes: Informing a Practice Changing Trial Accelerating the Translation of Cell Therapy for Type 1 Diabetes Supports researchers with tools to enhance scientific rigor, reproducibility, and transparency, and provides a big data knowledge base for genomic and pathway hypothesis generation.

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