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Digital Health (DH) Grant (NSF SBIR) is sponsored by National Science Foundation (NSF).
This grant supports entrepreneurs and startups in the earliest stages of developing innovative, differentiated, and novel technologies that aim to improve physical or mental well-being or health, enable or assist individuals to increase or regain independence and quality of life, and improve healthcare delivery, including efficiency, reducing cost, or improving outcomes.
Technologies in this portfolio include those applying AI in healthcare, personalized medicine, EHR/EMR, clinical decision support, and smart/connected medical devices. Specific sub-topics include Healthcare Workflow, Economics, and Delivery.
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Digital Health Grant – Apply Today | NSF SBIR Check recent critical alerts! (Last updated 4/16/2026) NSF will resume the submission of new Project Pitches to the SBIR/STTR programs in the coming weeks. Program Directors will continue to process Project Pitches that were previously received.
Please direct any questions to sbir@nsf. gov . The Neural Analytics Lucid™ M1 transcranial Doppler Ultrasound System is indicated as an adjunct to the standard clinical practices for measuring and displaying cerebral blood flow velocity within the major conducting arteries and veins of the head and neck.
Additionally, the Lucid™ M1 System measures the occurrence of transient emboli signals within the blood stream.
The Digital Health topic aims to support entrepreneurs and startups at the earliest-stages of development of innovative, differentiated and novel technologies that aim to improve physical or mental wellbeing or health, enable or assist individuals to increase or regain independence and quality of life and improve the delivery of healthcare including efficiency, reducing cost or improving outcomes.
Technologies in this portfolio include those applying AI in healthcare or general wellness (medical image analysis, personalized medicine, EHR/EMR, Clinical decision support, Computer aided diagnostics, support or therapy, smart/connected medical devices) as well as technologies that enable or provide assistance to aging or disabled populations and individuals undergoing rehabilitation. DH1.
Assistive, Enabling and Rehabilitative technologies DH2. AI in healthcare and drug discovery DH3. Healthcare Workflow, Economics and Delivery DH4.
Medical Diagnostics and Devices DH5. Physical, Mental and Behavioral Health DH6. Other Digital Health Technologies Application process for Digital Health (DH) funding Eligibility for Digital Health (DH) funding + Your company must be a small business (fewer than 500 employees) located in the United States.
At least 50% of your company’s equity must be owned by U.S. citizens or permanent residents. NSF does not fund companies that are majority-owned by multiple venture capital firms, private equity firms, or hedge funds, to participate in SBIR and STTR. All funded work, including work done by consultants and contractors, needs to take place in the United States.
The project’s principal investigator (tech lead) must be legally employed at least 20 hours a week by the company seeking funding. The principal investigator doesn’t need any advanced degrees. The principal investigator needs to commit to at least one month (173 hours) of work on a funded project per six months of project duration.
Evaluation Criteria: What We Look for When Evaluating Digital Health (DH) proposals + Take our project assessment to see if your work might be a good fit for NSF funding.
'Moxi' the robot that supports nurses Diligent Robotics, a small business funded by the National Science Foundation (NSF), created “Moxi,” a robot that supports clinical staff teams in acute care hospitals by executing logistical tasks so staff can focus on direct human care. To learn more visit: https://diligentrobots. com/ We invest up to $2 million in seed funding and take zero equity.
We’re looking for companies that are transformative, high-risk, have a market pull, and are scaleable.
Key questions and narrative sections extracted from the solicitation.
Project description (10–15 pages addressing innovation, technical approach, and R&D plan)
Commercialization strategy
Scoring criteria used to review proposals for this grant.
According to the current listing, eligibility includes: Small businesses (fewer than 500 employees) located in the United States, with at least 50% equity owned by U.S. citizens or permanent residents. The project's principal investigator must be legally employed at least 20 hours a week by the company and commit to at least one month of work per six months of project duration. Confirm the full requirements in the official notice before applying.
The published deadline was April 16, 2026, which has passed. Check the official notice for any future application windows before investing time in a proposal.
Digital Health (DH) Grant (NSF SBIR) is funded by National Science Foundation (NSF). Verify program details on the funder's official page before applying.
Yes — this listing is flagged as national in scope, so applicants across the U.S. may apply, subject to the sponsor's other eligibility criteria.
Applications go through the funder's official portal — the Apply Now link on this page goes there directly.
The solicitation lists 5 required documents: Project description (10–15 pages), Budget details, Biographical sketches, Commercialization strategy, and Intellectual property agreements (required for STTR; recommended for SBIR with subawards). Check the official notice for formatting and page-limit rules.
Past winners and funding trends for this program
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