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Digital Health Topic is sponsored by National Science Foundation (NSF) SBIR Program. This topic supports entrepreneurs and startups at the earliest stages of developing innovative, differentiated, and novel technologies that aim to improve physical or mental well-being or health, increase or regain independence and quality of life, and improve healthcare delivery.
Technologies include those applying AI in healthcare or general wellness, as well as assistive, enabling, and rehabilitative technologies.
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Or search similar grants →According to the current listing, eligibility includes: U.S.-based startups with fewer than 500 employees and at least 50% U.S. ownership. NSF does not fund companies that are majority-owned by multiple venture capital firms, private equity firms, or hedge funds. The project's principal investigator (tech lead) must be legally employed at least 20 hours a week by the company. Confirm the full requirements in the official notice before applying.
The current listing shows up to $305,000 for Phase I; up to $1,250,000 for Phase II (in some cases, additional funding of up to $500,000). Verify award ceilings, matching requirements, and allowable costs in the official notice.
Digital Health Topic is funded by National Science Foundation (NSF) SBIR Program. Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Past winners and funding trends for this program
NSF's $20 million Commercialization Readiness Pilot, announced September 14, 2026 and led by UCF's National Commercialization and Translation Institute, will give six to eight Phase II and IIB deep-tech firms milestone awards of $1 million to $3.75 million. Roughly one in ten NSF Phase IIB alumni will get a seat. Here is how the selection logic actually works.
Read articleNSF's restarted SBIR/STTR program carries two transition rules almost nobody has calendared. Project Pitch invitations issued on or after July 3, 2025 must be converted to a full proposal by November 4, 2026. Phase I awardees whose awards started on or after November 6, 2023 must submit Phase II by the same date. Both cohorts were created by the program lapse, and both cliffs are hard.
Read articleNSF's rebuilt SBIR/STTR program (NSF 26-510) pairs a $305,000 Phase I with a brand-new Strategic Breakthrough award worth up to $30 million for the strongest Phase II companies. The next Project Pitch deadline is July 27, 2026. Here is how the non-dilutive funding ladder now works, why the Project Pitch gate decides everything, and how a founder should sequence the next twelve months.
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