DOD Chronic Pain Management, Pain Management Collaborative Clinical Research Award (FY23 CPMRP PMCCRA)

DOD Chronic Pain Management, Pain Management Collaborative Clinical Research Award (FY23 CPMRP PMCCRA) is sponsored by Department of Defense (DOD) - Defense Health Agency Contracting Activity - DHACA. This award supports large-scale pragmatic comparative effectiveness and implementation science clinical trials to facilitate the acceptance and utilization of evidence-based chronic pain management clinical applications.

Chronic Pain Management Research Program | Office of Research Operations (ORO) | Stanford Medicine Office of Research Operations DoD Chronic Pain Management Research Program Clinical Exploration Award Amount of funding: Direct costs budgeted for the entire period of performance will not exceed $250,000.

Purpose: The intent of the FY23 CPMRP CEA is to support proof-of-principle pilot studies, clinical trials, and correlative studies to investigate hypothesis-based, innovative interventions and/or avenues of research that have the potential to resolve current clinical barriers and result in a profound impact on the management of chronic pain.

While therapeutic approaches proposed for testing through the CPMRP CEA must represent novel, hypothesis-based, “outside-the-box” approaches for managing chronic pain, they may include therapies already in clinical use, or undergoing clinical testing, for other diseases, provided that the proposed use for chronic pain management would lead to a major advancement in patient care.

Eligibility: Independent investigators - Faculty with PI eligibility and CE faculty (with an approved CE faculty PI waiver obtained through their RPM in RMG prior to the pre-application/letter of intent) may be PI. Not eligible : Instructors, Clinical Instructors, Academic staff-research (i.e., research associates), and postdocs are not eligible for this RFP because Stanford does not consider them to hold independent positions.

REQUIRED Pre-Application (Pre-Proposal) Deadline: August 21, 2023 via eBrap Please include your RPM’s name as business official in the pre-application. Institutional representative (RPM/RMG or CGO/OSR) Deadline: November 2, 2023 Application Submission Deadline: November 9, 2023 via grants. gov Guidelines : https://cdmrp.

health. mil/funding/cpmrp Investigator-Initiated Research Award Amount of funding: Direct costs budgeted for the entire period of performance will not exceed $900,000. Purpose: The intent of the FY23 CPMRP IIRA is to support studies that have the potential to make significant advances in the research, patient care, and/or quality of life in the FY23 CPMRP IIRA Focus Areas.

IIRA applications may involve basic, translational, and clinically oriented research, including studies in animal models, research with human anatomical substances, and research with human subjects, as well as correlative studies associated with an existing clinical trial; however, this award may not be used to conduct clinical trials. .

Eligibility: Independent investigators - Faculty with PI eligibility and CE faculty (with an approved CE faculty PI waiver obtained through their RPM in RMG prior to the pre-application/letter of intent) may be PI. Not eligible : Instructors, Clinical Instructors, Academic staff-research (i.e., research associates), and postdocs are not eligible for this RFP because Stanford does not consider them to hold independent positions.

REQUIRED Pre-Application (Pre-Proposal) Deadline: August 21, 2023 via eBrap Please include your RPM’s name as business official in the pre-application. Institutional representative (RPM/RMG or CGO/OSR) Deadline: November 2, 2023 Application Submission Deadline: November 9, 2023 via grants. gov Guidelines : https://cdmrp.

health. mil/funding/cpmrp Clinical Outcomes Research Award Amount of funding: Direct costs budgeted for the entire period of performance will not exceed $1. 4M.

Purpose: The intent of the FY23 CPMRP CORA is to support studies focused on improving clinical outcomes through late-stage translational efforts that will accelerate the movement of evidencebased ideas in chronic pain management into clinical applications, such as health care products, technologies, clinical practice guidelines, and/or models of care.

CORA applications should explain how the proposed work will inform the development, refinement, and/or revision of existing standards of care, recommendations, or guidelines for managing chronic pain. The FY23 CPMRP CORA is focused on identifying and implementing outcomes-based best practices through the analysis of the merits of pain management approaches, not on the development of new or novel techniques.

Eligibility: Independent investigators - Faculty with PI eligibility and CE faculty (with an approved CE faculty PI waiver obtained through their RPM in RMG prior to the pre-application/letter of intent) may be PI. Not eligible : Instructors, Clinical Instructors, Academic staff-research (i.e., research associates), and postdocs are not eligible for this RFP because Stanford does not consider them to hold independent positions.

REQUIRED Pre-Application (Pre-Proposal) Deadline: August 21, 2023 via eBrap Please include your RPM’s name as business official in the pre-application. Institutional representative (RPM/RMG or CGO/OSR) Deadline: November 2, 2023 Application Submission Deadline: November 9, 2023 via grants. gov Guidelines : https://cdmrp.

health. mil/funding/cpmrp Pain Management Collaborative Clinical Research Award Amount of funding: Direct costs budgeted for the entire period of performance will not exceed $500,000 for the 15-month planning phase award and $3. 0M for the full-scale clinical trial optional effort for a combined total direct cost of $3.

5M. Purpose: The intent of the FY23 CPMRP PMCCRA is to support large-scale pragmatic comparative effectiveness and implementation science clinical trials that will facilitate the acceptance and utilization of evidence-based chronic pain management clinical applications, such as health care products, technologies, clinical practice guidelines, and/or models of care.

PMCCRA applications should explain how the proposed work will inform the development, refinement, and/or revision of existing standards of care, recommendations, or guidelines for managing chronic pain. Military and Veterans health care systems and other health care entities that provide services to Service Members, Veterans, and their families are the targeted organizations for this program.

Research conducted in partnership with eligible VA and Military Health System (MHS) providers is essential for obtaining meaningful and relevant research results in “real world” health care delivery systems serving Veterans, Service Members, and their beneficiaries.

Eligibility: Independent investigators - Faculty with PI eligibility and CE faculty (with an approved CE faculty PI waiver obtained through their RPM in RMG prior to the pre-application/letter of intent) may be PI. Not eligible : Instructors, Clinical Instructors, Academic staff-research (i.e., research associates), and postdocs are not eligible for this RFP because Stanford does not consider them to hold independent positions.

REQUIRED Pre-Application (Pre-Proposal) Deadline: August 21, 2023 via eBrap Please include your RPM’s name as business official in the pre-application. Institutional representative (RPM/RMG or CGO/OSR) Deadline: November 2, 2023 Application Submission Deadline: November 9, 2023 via grants. gov Guidelines : https://cdmrp.

health. mil/funding/cpmrp Please include your institutional official's name (RPM/RMG or CGO/OSR) as business official in the pre-application/LOI.