DOD Peer Reviewed Alzheimer's Research Program FY25

DOD Peer Reviewed Alzheimer's Research Program FY25 is sponsored by U.S. Army Medical Research and Development Command (USAMRDC). Anticipated funding for impactful, solution-oriented research to address critical needs and improve the quality of life for Service Members, Veterans, their Families, and the public living with Alzheimer's disease (AD) and related dementias (ADRD).

DOD Peer Reviewed Alzheimer's Research Program FY25 | Research And Engagement Research And Engagement > Scholar Updates > DOD Peer Reviewed Alzheimer’s Research Program FY25 DOD Peer Reviewed Alzheimer’s Research Program FY25 Posted on December 12, 2024 Applications submitted to the FY25 PRARP must be relevant to one or more of the following priority areas: Reduce Risk and Prevent AD/ADRD Improve Diagnosis and Prognosis Improve Quality of Life for People Living With a Dementia Diagnosis In addition, the PRARP is interested in work that addresses and reduces health disparities in AD/ADRD research.

All FY25 PRARP mechanisms have a Career Initiation or Transition (CIT) Partnership Option to encourage research capacity in critical areas to include women’s health, military health and dementia care. The partnership option allows for two investigators with complementary research expertise to work collaboratively on one project. One investigator must meet the definition of Career Initiation or Career Transition.

For this option, the CIT investigator should have only nominal research support in the field and be either : (a) Career Initiation: a junior investigator three or more years from their terminal degree but no more than seven years into an independent position (b) Career Transition: transitioning from another field to the AD/ADRD/TBI field and has only nominal, if any, publications in the AD-related field.

The PI must be an independent investigator at any career level. Supports person-centered research that prioritizes both the individual with AD/ADRD and their care partner(s). The project should clearly demonstrate feasibility and a realistic approach to scaling and implementation.

“Care” does not refer to medical care (such as medical interventions administered by a physician) but is inclusive of all modalities and requirements of dementia care. There is no requirement for studies to be performed in a Veteran or military cohort. The PRARP encourages investigators to consider how their research from a civilian cohort might be applicable to such populations, and vice versa.

Community collaboration is required for all applications. Animal studies are not allowed. Clinical trials are allowed.

The CIT Option is available. Submission of a preproposal is required; application submission is by invitation only. Maximum funding of $1.

6 million (M) for total costs. Maximum period of performance is 4 years. Maximum funding of $1.

8M for total costs Transforming Diagnosis Award The PI must be an independent investigator at any career level. Supports research to reduce barriers and improve diagnosis and prognosis of dementia of AD/ADRD following military service and/or TBI. There is no requirement for studies to be performed in a Veteran or military cohort.

The PRARP encourages investigators to consider how their research from a civilian cohort might be applicable to such populations, and vice versa. Studies leveraging existing cohorts or data sets are encouraged. Community collaboration is required for all applications.

The CIT Option is available. Animal studies are not allowed. Submission of a preproposal is required; application submission is by invitation only Maximum funding of $1.

5M for total costs. Maximum period of performance is 4 years. Maximum funding of $1.

7M for total costs Transforming Research Award The PI must be an independent investigator at any career level. Research must address the priority area of “Reduce risk and prevent AD/ADRD. ” Supports high-impact research aimed to identify, validate, and/or mitigate risk factors that may contribute to dementia onset.

Clinical trials are not supported, but studies with prospective human subjects’ enrollment may be allowed. Applications proposing clinical studies will require community collaboration. Studies leveraging existing cohorts or data sets are encouraged.

Animal studies that are fully justified for relevance to human health are allowed. Community collaboration is not required for projects that focus primarily on animal studies but is encouraged. The CIT Option is available.

Submission of a preproposal is required; application submission is by invitation only. Maximum funding of $1. 0M for total costs.

Maximum period of performance is 3 years. Maximum funding of $1. 0M for total costs usarmy.

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