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The Department of Energy's Genesis Mission is a landmark $293. 76 million funding opportunity (DE-FOA-0003612) to accelerate scientific discovery and R&D workflows using novel artificial intelligence models and frameworks.
Jointly managed by DOE's Office of Science, Office of Critical Minerals and Energy Innovation, Office of Environmental Management, Office of Nuclear Energy, Office of Electricity, and Hydrocarbons and Geothermal Office, the program addresses over 26 national science and technology challenges.
It supports deployment-ready AI solutions across energy systems, grid infrastructure, data centers, advanced manufacturing, microelectronics, biotechnology, critical materials, nuclear fission and fusion, quantum information science, semiconductors, and discovery science. Applications follow a two-phase structure: Phase I for small teams and Phase II for large interdisciplinary teams.
Key milestone dates include Phase 1 applications due April 28, 2026, Phase II applications due May 19, 2026, with the overall opportunity closing December 17, 2026. Applicants must address intellectual property allocation in multi-party collaborations, data governance protocols, DOE procurement compliance, export controls, and cybersecurity requirements.
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Or search similar grants →According to the current listing, eligibility includes: Unrestricted eligibility. Interdisciplinary teams from universities, national laboratories, industry, and nonprofits are welcome. Applicants must demonstrate capacity for deployment-ready AI solutions and address IP allocation, data governance, and compliance requirements. Confirm the full requirements in the official notice before applying.
The current listing shows total program funding of $293.76 million. Individual awards range from $500,000 minimum to $16,000,000 maximum. Phase I supports small teams and Phase II supports large interdisciplinary teams. Verify award ceilings, matching requirements, and allowable costs in the official notice.
Applications for DOE Genesis Mission National Science and Technology Challenges for AI-Accelerated Scientific Discovery and Energy Innovation are due December 17, 2026. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
DOE Genesis Mission National Science and Technology Challenges for AI-Accelerated Scientific Discovery and Energy Innovation is funded by Department of Energy. Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
The NSF Computer and Information Science and Engineering: Future Computing Research (Future CoRe) program (NSF 25-543) supports foundational computing research and education with a strong emphasis on AI and machine learning. The program funds research that advances the foundations of computing including AI/ML theory, algorithms, systems, and applications. Future CoRe supports small to medium-sized research projects that can have significant impact on computing foundations. The program has target dates of February 5, 2026 and September 10, 2026 for proposal submissions (note: these are target dates, not deadlines, meaning proposals may be submitted at any time but will be reviewed in batches around these dates). Investigators may not serve as PI, co-PI, or Senior/Key Personnel on more than two proposals submitted within any consecutive 12-month period across all Future CoRe programs. This is one of NSF's primary mechanisms for funding fundamental AI and machine learning research at U.S. academic institutions, covering areas such as machine learning theory, natural language processing, computer vision, robotics foundations, and human-AI interaction.
The ONR Long Range Broad Agency Announcement (N00014-25-S-B001) is the Office of Naval Research's primary mechanism for soliciting research proposals across all naval science and technology priority areas. The BAA accepts proposals on a rolling basis through September 30, 2026 and covers ONR's full spectrum of research interests with particular emphasis on AI-related topics including autonomous maritime systems, human-machine teaming, machine learning for sensor fusion, cooperative autonomous swarm technology, undersea autonomy, and AI-enabled decision superiority. Proposals can be funded through multiple mechanisms including individual investigator grants, the Young Investigator Program (~$510K over 3 years for early-career faculty), and Multidisciplinary University Research Initiative (MURI) awards ($1.5M/year for 3-5 years for research teams). ONR recommends contacting relevant program officers before submitting to discuss alignment with current research priorities. The BAA supports basic research (6.1), applied research (6.2), and advanced technology development (6.3) across the full range of naval-relevant science and engineering disciplines.
DE-FOA-0003600 is the DOE Office of Science's FY 2026 open, rolling solicitation for financial assistance, providing roughly $500 million across seven program areas: Advanced Scientific Computing Research, Basic Energy Sciences, Biological and Environmental Research, Fusion Energy Sciences, High Energy Physics, Nuclear Physics, and Isotope R&D and Production. AI and machine learning research is supported directly through Advanced Scientific Computing Research, while Biological and Environmental Research funds atmospheric process research, environmental systems process research, and earth-energy systems modeling — making this a major channel for AI-enhanced climate and earth system modeling work. DOE anticipates 200 to 350 new awards ranging from $5,000 to $5 million each, with project periods from six months to five years. The FOA opened September 30, 2025 and accepts applications on a rolling basis through the end of FY 2026.
On September 21, 2026 DOE selected 21 projects under DE-FOA-0003472 — five EGS field tests and 16 exploration wells — for up to $99 million of a $171.5 million authorization. The solicitation is structured to reopen for up to 72 months on roughly annual cycles. Here is how to position for the next one.
Read articleDOE named 31 grid projects across 26 states for $1.9B on September 24, 2026. Recipients bring $3.35B of their own money. Here is what the selection list reveals about how to win the next GRIP round.
Read articleThe DOE Quantum Genesis Q Competition (DE-FOA-0003657) posted September 17, 2026 with an October 19 deadline. Phase I pays $250,000 then $1.25M on milestones; Phase II is a $100M pool plus two $50M bonus pools at 150 and 200 logical qubits. It is an Other Transaction Agreement, not a grant.
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