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Find similar grantsExploratory/Developmental Research Grant Program (R21) is sponsored by National Institute of Mental Health (NIMH) / NIH. This program encourages exploratory and developmental research projects in all NIMH-relevant scientific areas by providing support for the early and conceptual stages of these projects.
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NIH Websites Are Changing Opportunities & Announcements Funding Strategy for Grants Grant Writing & Approval Process Non-Clinical trial R21 applications NIMH accepts non-clinical trial R21 applications under the following opportunities: PA-25-304: NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Not Allowed) PA-25-150: Joint NINDS/NIMH Exploratory Neuroscience Research Grant (R21 Clinical Trial Not Allowed) Applications must support exploratory and foundational research projects aligned with the NIMH scientific mission .
Clinical trial R21 applications NIMH accepts mechanistic clinical trial R21 applications under the following opportunities: PA-25-306: NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required) PA-25-307: NIH Exploratory/Developmental Research Project Grant (Parent R21 Basic Experimental Studies with Humans Required) See the Consolidated Notice on NIMH Clinical Trials Policies (NOT-MH-23-375 ), for a summary of NIMH’s polices on support for mechanistic and other clinical trials.
Potential applicants are strongly encouraged to contact the Agency Contacts listed in the targeted funding opportunity before applying. NIMH Extramural Research Programs: Review to understand the broad range of scientific fields supported by NIMH.
According to the current listing, eligibility includes: See official notice (generally, institutions and organizations). Confirm the full requirements in the official notice before applying.
The current listing shows up to $275,000 over two years, with no single year exceeding $200,000. Verify award ceilings, matching requirements, and allowable costs in the official notice.
Exploratory/Developmental Research Grant Program (R21) is funded by National Institute of Mental Health (NIMH) / NIH. Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Notice of Special Interest (NOSI): SBIR/STTR High-Priority Areas for Digital Mental Health Innovations is sponsored by National Institute of Mental Health (NIMH) / NIH. This NOSI encourages Small Business Concerns (SBCs) to submit SBIR and STTR grant applications for developing, refining, and evaluating digital mental health technologies. This includes mobile health (mHealth) and health information technology.
Notice of Special Interest (NOSI): SBIR/STTR High-Priority Areas for Digital Mental Health Innovations (NOT-MH-24-120) is sponsored by National Institute of Mental Health (NIMH) / NIH. This NOSI encourages Small Business Concerns (SBCs) to submit SBIR and STTR grant applications that propose to develop, refine, and evaluate digital mental health technologies.
The Health and Extreme Weather highlighted topic went live September 1, 2026 with eleven awarding institutes and expires May 1, 2028. There is no set-aside, no separate deadline, and no review criteria — which makes the institute-by-institute language the only real signal, and it is not uniform.
Read articleThe NOURISH Autoimmunity Digital Health Challenge runs three phases to August 2028: 10 winners at $20,000, then 5 at $30,000, then 3 at $100,000. It is a prize competition, not a grant — no indirect costs, no cost reimbursement, and a rule that quietly disqualifies the obvious applicant.
Read articlePMHCA (HRSA-26-058) makes $9.79 million available for up to 22 awards of up to $445,000 to build tele-consultation networks that help pediatric primary care providers manage children's behavioral health. The catch buried in the eligibility section: applicants must NOT already hold a PMHCA award — which effectively reserves the new-state lane for the eight unfunded states and territories, plus tribes everywhere. Here's how to read it and what wins.
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