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ActiveU.S. Food and Drug Administration (FDA) · 2026

FDA Small Business Innovation Research (SBIR) Program

Quick Facts

Agency: U.S. Food and Drug Administration (FDA)
Funding: Phase I: $50,000 - $275,000; Phase II: $750,000 - $1.8 million
Deadline: Check Source
Status: Active
Eligibility: Small businesses that are organized for profit, located in the United States, at least 51% owned and controlled by U. S. citizens or permanent resident aliens, and have no more than 500 employees.

About This Grant

FDA Small Business Innovation Research (SBIR) Program is sponsored by U.S. Food and Drug Administration (FDA). This opportunity supports mission-aligned projects and measurable outcomes.

View Original RFP

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Official Opportunity Details

Extracted from the official opportunity page/RFP to help you evaluate fit faster.

Opportunity Listing - NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional) Agency: National Institutes of Health Assistance Listings: 93. 068 -- Chronic Diseases: Research, Control, and Prevention 93. 351 -- Research Infrastructure Programs 93.

083 -- Prevention of Disease, Disability, and Death through Immunization and Control of Respiratory and Related Diseases 93. 350 -- National Center for Advancing Translational Sciences 93. 273 -- Alcohol Research Programs 93.

867 -- Vision Research 93. 859 -- Biomedical Research and Research Training 93. 326 -- Strengthening Public Health through Surveillance, Epidemiologic Research, Disease Detection and Prevention 93.

847 -- Diabetes, Digestive, and Kidney Diseases Extramural Research 93. 395 -- Cancer Treatment Research 93. 879 -- Medical Library Assistance 93.

073 -- Birth Defects and Developmental Disabilities - Prevention and Surveillance 93. 393 -- Cancer Cause and Prevention Research 93. 084 -- Prevention of Disease, Disability, and Death by Infectious Diseases 93.

233 -- National Center on Sleep Disorders Research 93. 394 -- Cancer Detection and Diagnosis Research 93. 173 -- Research Related to Deafness and Communication Disorders 93.

070 -- Environmental Public Health and Emergency Response 93. 121 -- Oral Diseases and Disorders Research 93. 136 -- Injury Prevention and Control Research and State and Community Based Programs 93.

840 -- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders 93. 865 -- Child Health and Human Development Extramural Research 93. 846 -- Arthritis, Musculoskeletal and Skin Diseases Research 93.

837 -- Cardiovascular Diseases Research 93. 172 -- Human Genome Research 93. 279 -- Drug Use and Addiction Research Programs 93.

855 -- Allergy and Infectious Diseases Research 93. 286 -- Discovery and Applied Research for Technological Innovations to Improve Human Health 93. 113 -- Environmental Health 93.

839 -- Blood Diseases and Resources Research 93. 213 -- Research and Training in Complementary and Integrative Health 93. 103 -- Food and Drug Administration Research 93.

143 -- NIEHS Superfund Hazardous Substances_Basic Research and Education 93. 361 -- Nursing Research 93. 307 -- Minority Health and Health Disparities Research 93.

242 -- Mental Health Research Grants 93. 313 -- NIH Office of Research on Women's Health 93. 142 -- NIEHS Hazardous Waste Worker Health and Safety Training 93.

853 -- Extramural Research Programs in the Neurosciences and Neurological Disorders 93. 838 -- Lung Diseases Research Last Updated: June 1, 2026 View version history on Grants. gov The Small Business Innovation Research (SBIR) program helps United States small business concerns (SBCs) bring scientific innovations to the marketplace.

The SBIR program supports feasibility studies to later research and development (R&D) needed to develop a commercial product. Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir. gov/apply) are eligible to submit applications for this opportunity.

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.

Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Unfunded international collaborations or unfunded foreign components, as defined in the NIH Grants Policy Statement, may be allowed.

Grantor contact information NIH SEED (Small business Education and Entrepreneurial Development) NIH SEED (Small business Education and Entrepreneurial Development) File name Description Last updated PA-27-100-Revised-Full-Announcement. html PA-27-100-Revised-Full-Announcement.

html Link to additional information Funding opportunity number : Cost sharing or matching requirement : Funding instrument type : Opportunity Category Explanation : Category of Funding Activity : Your account requires additional identity verification.

Eligibility Requirements

Small businesses that are organized for profit, located in the United States, at least 51% owned and controlled by U. S. citizens or permanent resident aliens, and have no more than 500 employees.

Frequently Asked Questions

Who can apply for FDA Small Business Innovation Research (SBIR) Program?

According to the current listing, eligibility includes: Small businesses that are organized for profit, located in the United States, at least 51% owned and controlled by U. S. citizens or permanent resident aliens, and have no more than 500 employees. Confirm the full requirements in the official notice before applying.

How much funding does FDA Small Business Innovation Research (SBIR) Program offer?

The current listing shows phase I: $50,000 - $275,000; Phase II: $750,000 - $1.8 million. Verify award ceilings, matching requirements, and allowable costs in the official notice.

Who funds FDA Small Business Innovation Research (SBIR) Program?

FDA Small Business Innovation Research (SBIR) Program is funded by U.S. Food and Drug Administration (FDA). Verify program details on the funder's official page before applying.

How do I apply for FDA Small Business Innovation Research (SBIR) Program?

Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.

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