FPWR Grant Program

FPWR Grant Program is sponsored by Foundation for Prader-Willi Research (FPWR). Supports innovative research into Prader-Willi syndrome (PWS) and Schaaf-Yang syndrome (SYS), focusing on areas like genetics, neurobiology, and therapeutic development.

FPWR Grant Program - Foundation for Prader-Willi Research First Steps Parents Package Puberty and Sexual Development Growth Hormone Therapy for PWS Social Skills Challenges & Strategies Mindfulness for Caregivers & People with PWS Parent's Guide for Supporting Siblings Building Our Social Skills (BOSS) Curriculum Scientific Advisory Board Clinical Trial Consortium Clinical Collaborative (CLIC) Therapeutics in Development Become an Advocate Reviewer FPWR Grant Program and Request for Applications The Foundation for Prader-Willi Research (FPWR), a nonprofit organization dedicated to supporting research to advance the understanding and treatment of Prader-Willi syndrome (PWS) and Schaaf-Yang syndrome (SYS), announces the availability of funds to support innovative PWS and SYS research.

FPWR is particularly interested in supporting projects that will lead to new treatments to alleviate the symptoms associated with PWS and SYS. A full description of FPWR's funding priorities can be found here .

Briefly, funding priority areas include: Genotype to phenotype: understanding PWS genetics / how loss of PWS-critical region genes leads to the phenotype Neurobiology of hunger / feeding behavior and metabolism in PWS Neurobiology of cognition, maladaptive behavior, and mental health in PWS Clinical care research: evaluation of existing drugs and interventions to improve the significant clinical concerns in PWS Therapeutics development for PWS- Genetic therapies; novel or repurposed pharmaceuticals; and devices Funds Available: Applicants may request up to $150,000 USD in direct costs for the initial 18 months of support, with the possibility of a second grant period of 18 months of funding upon competitive renewal.

Indirect costs of up to 8% are allowed. Applicants may choose to request a smaller budget and/or shorter duration, for example, for a higher risk / highly innovative project. Eligibility: FPWR accepts applications from academic, government, non-profit or for-profit research entities from within and outside the United States.

Principal Investigators must have a primary faculty appointment at the level of Instructor or higher. This grant program will be useful for junior faculty in the early stages of their careers, established investigators in other areas of research who wish to enter the field of PWS/SYS research, or investigators in the PWS/SYS field who are seeking funding to support pilot studies in a new area of PWS/SYS research.

FPWR seeks to support innovative, high-risk/high reward research, and supports research internationally. Application Review and Award: Letters of intent (LOI) will be reviewed for innovation and potential impact, merit and relevance to the mission of FPWR. Selected LOIs will be invited to submit a full grant proposal.

Full grant proposals meeting the technical requirements will be reviewed on the basis of merit by scientific reviewers with expertise in the research area. An advocate reviewer will evaluate the relevance of the proposed research to the PWS and/or SYS community. Final funding decisions will be based on scientific merit, relevance and the suitability of the research with respect to the programmatic goals of FPWR.

Application Guidelines: All LOIs and applications are to be submitted online through ProposalCentral . The LOI is limited to a 2-page description. Full grant proposals are limited to a 5-page research plan.

Guidelines and instructions can be found on ProposalCentral. Please follow the links for scientific and advocate review considerations, and a list of previously funded projects. Grant Application Deadlines FPWR is proud to offer two grant cycles a year!

Letters of Intent due September 4th, 2026 Proposals due November 13th, 2026 Letters of Intent due February 26th, 2027 Proposals due May 14th, 2027 FPWR also welcomes highly integrated, multi-disciplinary research teams to address ambitious and challenging research questions that are important for the mission of FPWR and are beyond the scope of one or two investigators.

If your project fits into this category, please contact Theresa Strong ( theresa. strong@fpwr. org ).

The Foundation for Prader-Willi Research (federal tax id 31-1763110) is a nonprofit corporation with federal tax exempt status as a public charity under section 501(c)(3). The mission of FPWR is to eliminate the challenges of Prader-Willi syndrome through the advancement of research and therapeutic development. Foundation for Prader-Willi Research