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Funding Opportunity Announcement for Impact of Environmental Exposures on Gut-Brain Signaling in Neurological Conditions (R01) is sponsored by National Institute of Environmental Health Sciences (NIEHS). This forecasted NOFO will solicit applications for research that builds on the understanding of the gut microbiome-brain axis to identify improved detection, prevention, and intervention strategies for environmental exposure-induced neurological diseases.
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gov Maintenance Calendar # View Grant Opportunity Forecast Funding Opportunity Announcement for Impact of Environmental Exposures on Gut-Brain Signaling in Neurological Conditions (R01) Department of Health and Human Services National Institutes of Health Note: This is a Forecasted Opportunity.
Document Type:Grants Notice Opportunity Number:TEMP-31126 Opportunity Title:Funding Opportunity Announcement for Impact of Environmental Exposures on Gut-Brain Signaling in Neurological Conditions (R01) Opportunity Category:Discretionary Opportunity Category Explanation: Funding Instrument Type:Grant Category of Funding Activity:Health Expected Number of Awards:8 Assistance Listings:93.
113 -- Environmental Health Cost Sharing or Matching Requirement:No Forecasted Date:Jul 18, 2025 Last Updated Date:Jul 18, 2025 Estimated Post Date:Oct 27, 2025 Estimated Application Due Date:Jan 15, 2026 Estimated Award Date:Jul 01, 2026 Estimated Project Start Date:Jul 01, 2026 Estimated Total Program Funding:$ 4,000,000 Eligible Applicants:Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Others (see text field entitled "Additional Information on Eligibility" for clarification) Private institutions of higher education Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Additional Information on Eligibility:Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
## Additional Information Agency Name:National Institutes of Health Description:The National Institute of Environmental Health Sciences (NIEHS) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research that builds on our understanding of the gut microbiome-brain axis for the purpose of identifying improved detection, prevention, and intervention strategies for environmental exposure-induced neurological diseases.
Given the overlapping gut-brain signaling pathways and the prevalence of neurological conditions with gut-related comorbidities, the scope of this program would be inclusive of a wide range of neurological outcomes, including mental health disorders and chronic neurodegenerative conditions such as Parkinson’s disease and Alzheimer’s disease.
The objective of this program is to develop gut-focused intervention strategies (e.g., probiotics, microbial biomarkers, nutritional supplements and novel therapeutics) to decrease risk, slow progression, or possibly reverse these neurological condition(s). Applications are not being solicited at this time.
Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the R01 activity code.
Investigators with expertise and insights into this area of biological mechanisms underlying the effects of environmental exposures on neurological outcomes and the mediating role of the gut-brain axis are encouraged to begin to consider applying for this new NOFO.
In addition, collaborative investigations combining expertise in toxicology, microbiome, and neuroscience will be encouraged and these investigators should also begin considering applying for this application. Link to Additional Information:[](https://example. hhsops.
gov/search-results-detail/359020) Grantor Contact Information:Anika L. Dzierlenga, Ph. D.
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According to the current listing, eligibility includes: Eligible applicants include various government, business, non-profit, and educational institutions. Foreign components are allowed. Confirm the full requirements in the official notice before applying.
Funding Opportunity Announcement for Impact of Environmental Exposures on Gut-Brain Signaling in Neurological Conditions (R01) is funded by National Institute of Environmental Health Sciences (NIEHS). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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