Gastrointestinal Microbiology & Infectious Diseases Research Program

Gastrointestinal Microbiology & Infectious Diseases Research Program is sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). This opportunity supports mission-aligned projects and measurable outcomes.

Gastrointestinal Microbiology & Infectious Diseases - NIDDK NIH Websites Are Changing Research Programs & Contacts Gastrointestinal Microbiology & Infectious Diseases Gastrointestinal Microbiology & Infectious Diseases Research on the gut microbiota and pathogenic organisms that reside in the gastrointestinal tract.

The Gastrointestinal Microbiology and Infectious Diseases program supports basic, clinical, and translational research on the gut microbiota, pathogenic organisms that reside in the gastrointestinal tract, and the host-microbial interactions that affect host physiology and the pathophysiology of digestive diseases and nutrition.

In particular, the program focuses on research characterizing the structure and function of the intestinal microbiome; mechanisms by which organisms of the microbiome contribute to disease processes in the gastrointestinal tract; innate immunity and inflammation, barrier function and gut permeability; the interaction between diet and the microbiome as it relates to nutrient metabolism, energy balance and metabolic disease; impact of gut microbiome on the gut-brain axis, bile acid metabolism and characterization of the role of microbial metabolites in physiological functions; the host response to gastrointestinal infections, such as Helicobacter pylori , Clostridium difficile , pathogenic Escherichia coli , Vibrio cholera, and enteric viruses; and the interactions between the mucosal immune system and the intestinal microbiome to maintain normal homeostasis or imbalance leading to inflammation and disease pathophysiology.

R. Dwayne Lunsford, Ph. D.

Host-microbial Interactions, Pathogenesis and Microbiomes Nutrient Metabolism; Clinical Obesity and Nutrition HIV/AIDS comorbidities, complications, coinfections Intestinal mucosal biology and pathology; stem cells; host-pathogens and microbiota interactions; celiac disease Terez Shea-Donohue, Ph. D.

Basic and Translational Neurogastroenterology, Gastrointestinal Motility, Gastrointestinal Barrier Function, Mucosal Immunology and Inflammation NIDDK Grant Opportunities Highlighted Topics of Interest to NIDDK NIDDK Active Trials in Digestive Disease View related clinical trials from ClinicalTrials. gov. Study sections conduct initial peer review of applications in a designated scientific area.

Visit the NIH’s Center for Scientific Review website to search for study sections. NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.

Ancillary Studies to Major Ongoing Clinical Studies to extend our knowledge of the diseases being studied by the parent study investigators under a defined protocol or to study diseases and conditions not within the original scope of the parent study but within the mission of the NIDDK. NIDDK Central Repository for access to clinical resources including data and biospecimens from NIDDK-funded studies.

NIDDK Information Network (dkNET) for simultaneous search of digital resources, including multiple datasets and biomedical resources relevant to the mission of the NIDDK. Mouse Phenotyping Centers Integrated Islet Distribution Program Additional Research Programs NIDDK supports the training and career development of medical and graduate students, postdoctoral fellows, and physician scientists through institutional and individual grants.

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Learn about Human Subjects Research Learn about NIDDK Translational Research Opportunities Supports researchers with tools to enhance scientific rigor, reproducibility, and transparency, and provides a big data knowledge base for genomic and pathway hypothesis generation.

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