Global Infectious Disease Research Training Program (D43 Clinical Trial Optional)

The Global Infectious Disease Research Training Program (D43) is a grant from the Fogarty International Center and NIAID at the NIH that funds collaborative research training programs to strengthen infectious disease research capacity in low- and middle-income countries (LMICs). Priority areas include antimicrobial resistance (AMR) and infectious disease surveillance, particularly at African institutions.

Applications must be submitted jointly by a U.S. institution of higher education and an equivalent non-U.S. institution in an LMIC. Awards range from $250,000 to $1,500,000 per year. The application deadline is August 6, 2026.

This is an ongoing funding opportunity announcement with multiple application receipt dates.

PAR-24-174: Global Infectious Disease Research Training Program (D43 Clinical Trial Optional) This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission. Department of Health and Human Services Part 1.

Overview Information Participating Organization(s) National Institutes of Health ( NIH ) Components of Participating Organizations Fogarty International Center ( FIC ) National Institute of Allergy and Infectious Diseases ( NIAID ) Special Note : Not all NIH Institutes and Centers participate in Parent Announcements.

Applicants should carefully note which ICs participate in this announcement and view their respective areas of research interest and requirements at the Table of IC-Specific Information, Requirements and Staff Contacts website. ICs that do not participate in this announcement will not consider applications for funding. Consultation with NIH staff before submitting an application is strongly encouraged.

Funding Opportunity Title Global Infectious Disease Research Training Program (D43 Clinical Trial Optional) D43 International Research Training Grants Notices of Special Interest associated with this funding opportunity March 31, 2025 - This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.

April 04, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25, 2025. See Notice NOT-OD-24-084 June 5, 2024 - Notice of Change to Funding Opportunity - Update of Foreign Eligibility Criteria for Global Infectious Disease Research Training Program (D43 Clinical Trial Optional).

See Notice NOT-TW-24-007 October 26, 2022 - Reminder: FORMS-H Grant Application Forms & Instructions Must be Used for Due Dates On or After January 25, 2023 - New Grant Application Instructions Now Available See Notice NOT-OD-23-012 August 8, 2022 - New NIH "FORMS-H" Grant Application Forms and Instructions Coming for Due Dates on or after January 25, 2023 See Notice NOT-OD-22-195 Funding Opportunity Number (FON) Companion Funding Opportunity See Section III.

3. Additional Information on Eligibility. Assistance Listing Number(s) Funding Opportunity Purpose This Funding Opportunity Announcement (FOA) encourages joint applications for the Global Infectious Disease (GID) Research Training programs from low- and middle-income country (LMIC) and U.S. institutions.

The application should propose a collaborative training program that will strengthen the capacity of a LMIC institution to conduct infectious disease research (not including HIV/AIDS).

FIC will support research training programs that focus on 1) major endemic or life-threatening emerging infectious diseases, 2) neglected tropical diseases, 3) infections that frequently occur as co-infections in HIV infected individuals or 4) infections or microbiomes associated with non-communicable disease conditions of public health importance in LMICs.

Advanced scientific training related to prevention, treatment or public health approaches to any technical area of basic, epidemiological, clinical, behavioral or social science health research may be supported.

Research training programs should incorporate didactic, mentored research and professional development skills components to prepare individuals for sustainable careers that will have significant impact on the priority health research needs of LMICs.

This Notice of Funding Opportunity (NOFO) allows appointment of Trainees (D43) proposing to serve as the lead investigator of an independent clinical trial; or proposing a separate ancillary clinical trial; or proposing to gain research experience in a clinical trial led by another investigator, as part of their research and career development.

Open Date (Earliest Submission Date) Letter of Intent Due Date(s) The letter of intent is due 30 days before the application due date. Renewal / Resubmission / Revision (as allowed) AIDS - New/Renewal/Resubmission/Revision, as allowed All applications are due by 5:00 PM local time of applicant organization.

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date. Required Application Instructions It is critical that applicants follow the Training (T) Instructions in the How to Apply Application Guide, except where instructed to do otherwise (in this NOFO or in a Notice from the NIH Guide for Grants and Contracts ).

Conformance to all requirements (both in the How to Apply Application Guide, and the NOFO) is required and strictly enforced. Applicants must read and follow all application instructions in the How to Apply Application Guide, as well as any program-specific instructions noted in Section IV. When the program-specific instructions deviate from those in the How to Apply Application Guide, , follow the program-specific instructions.

Applications that do not comply with these instructions may be delayed or not accepted for review. There are several options available to submit your application through Grants. gov to NIH and Department of Health and Human Services partners.

You must use one of these submission options to access the application forms for this opportunity. Use the NIH ASSIST system to prepare, submit and track your application online. Use an institutional system-to-system (S2S) solution to prepare and submit your application to Grants.

gov and eRA Commons to track your application. Check with your institutional officials regarding availability. Workspace to prepare and submit your application and eRA Commons to track your application.

Part 1. Overview Information Part 2. Full Text of Announcement Section I.

Funding Opportunity Description Section II. Award Information Other Award Budget Information Section III. Eligibility Information Section IV.

Application and Submission Information Section V. Application Review Information Section VI. Award Administration Information Section VII.

Agency Contacts Section VIII. Other Information Part 2. Full Text of Announcement Section I.

Funding Opportunity Description Purpose and Background Information Infectious diseases continue to impose a tremendous health burden in resource-poor countries throughout the world, claiming millions of lives annually and inflicting severe morbidity that results in significant losses in economic productivity and social progress.

Attempts to control infectious diseases endemic to low- and middle-income countries (LMICs) suffer due to an incomplete understanding of the pathogens, disease manifestations and transmission mechanisms, inadequate preventive measures and interventions, and insufficient health services and disease control efforts.

A major barrier to improved, evidence-based treatment and control of infectious diseases in LMICs is insufficient capacity to conduct locally relevant infectious disease research. LMIC scientists and health professionals with relevant research expertise can generate new knowledge and strategies for infectious disease prevention and healthcare implementation to address high priority needs in their countries.

Therefore, the overall intent of this funding opportunity is to engender scientific knowledge and skills in LMIC trainees that will enhance capacity at LMIC institutions to conduct research directly related to prevention, treatment and control of infectious diseases causing major morbidity and mortality. Applications that include LMICs with little current research capacity are especially encouraged.

This announcement encourages joint applications for the Global Infectious Disease Research Training program from LMIC and U.S. research institutions. FIC will support innovative research training programs that are designed to build sustainable infectious disease research capacity at an institution in an endemic LMIC.

Sustainable infectious disease research capacity is known to require a critical mass of scientists and health research professionals with in-depth scientific expertise and complementary leadership skills that enable the institution to conduct independent, internationally recognized infectious disease research relevant to the health priorities of their country.

The application should propose a collaborative research training program that will strengthen the capacity of a LMIC institution to conduct infectious disease research that focuses on 1) major endemic or life-threatening emerging infectious diseases, 2) neglected tropical diseases, 3) infections that frequently occur as co-infections in HIV infected individuals, or 4) infections or microbiomes associated with non-communicable disease conditions of public health importance in LMICs.

Advanced scientific training related to infectious disease prevention, treatment or public health approaches in any technical area of basic, epidemiology, clinical, behavioral or social science health research may be supported.

Research training programs should incorporate didactic, mentored research and professional development skills components to prepare individuals for sustainable careers that will have significant impact on the priority health research needs of LMICs. This program does not support HIV/AIDS research training.

Applicants interested in HIV research training should apply to the Fogarty HIV Research Training Program funding opportunities (see http://www. fic. nih.

gov/Programs/Pages/hiv-aids-research-training. aspx ). The objectives of the Global Infectious Disease Research Training program are: - To develop research training opportunities and professional development activities for a collaborative group of LMIC scientists and health research professionals at an LMIC institution to strengthen its capacity to conduct independent, sustainable infectious disease research.

- To provide mentored infectious disease research experience that is directly relevant to the health priorities of the LMIC of the trainees. - To strengthen the capabilities of trainees at the proposed LMIC institution to lead, manage and train others in infectious disease research.

Each program should provide LMIC trainees rigorous research training, i.e., relevant advanced coursework, mentored research experience and appropriate technical and professional skills' development.

Research training should provide each LMIC trainee with: A strong foundation in research design, methods, and analytic techniques appropriate for the proposed infectious disease research area; Enhancement of their ability to conceptualize and analyze research problems with increasing independence; Experience conducting infectious disease research using state-of-the-art methods as well as presenting and publishing their research findings; Opportunities to interact with members of the scientific community at relevant scientific meetings and workshops; and The enhancement of their overall understanding of the health-related sciences and the relationship of their research training to the health and disease situation in their LMIC.

Research Capacity: The Global Infectious Disease Research Training programs should be designed to move beyond training a number of individuals for the next career level to demonstratively increasing sustainable, independently resourced infectious disease research capacity at the proposed LMIC institution.

It is expected that the training strategies proposed will contribute to measurable enhancement of explicitly defined infectious disease research capacity outcomes.

Other LMIC institution research training programs: The proposed institutional infectious disease research training program may complement other ongoing research training and career development programs at the LMIC institution, but the proposed program must be clearly distinct from related programs.

As stated in the rationale for a proposed training program, applications must identify an infectious disease scientific focus directly relevant to the LMIC health priorities for which research capacity is limited at the LMIC institution. Applications may focus on research training on infectious diseases which are: 1) Major endemic (malaria, tuberculosis, etc.) or life-threatening emerging infectious diseases ( https://www. niaid.

nih. gov/research/emerging-infectious-diseases-pathogens ) 2) Neglected tropical diseases ( https://www. niaid.

nih. gov/research/neglected-tropical-diseases-types ) 3) Infections or microbiomes associated with non-communicable disease conditions of public health importance or 4) Infections that frequently occur as co-infections in HIV infected individuals. However, applications that focus exclusively on research training to address HIV/AIDS or co-infections in the context of HIV will not be supported in this program.

This FOA can support research training related to infectious disease prevention, care and treatment in a broad range of technical areas: basic, epidemiologic, clinical, behavioral, and social science research; bioinformatics, biostatistics, disease modeling; pathophysiology, diagnostics and therapeutics research; implementation, health economics, health services and systems research or; Applicants are also encouraged to design multidisciplinary research training programs with a focus on a global infectious disease cross-cutting theme, for example, common modes of transmission, pathophysiology or virulence such as (but not limited to): environmental transmission (air, water, soil, etc.); anti-microbial resistance; Training PDs/PIs are encouraged to develop training programs that will expose LMIC trainees to a diversity of scientific approaches, systems for study, research approaches, and tools and technologies.

The research training should incorporate research methods, and processes that enhance r esearch rigor and reproducibility ( https://grants. nih. gov/policy/reproducibility/training.

htm ). Consideration of team-based research approaches may also be warranted depending upon the goals of the proposed training program. The program application should incorporate an appropriate mix of training opportunities to address the infectious disease-related research training capacity needs identified at the LMIC institution.

Advanced degree or non-degree research training may be supported at a U.S. or foreign institution. Research trainees who are also training as clinicians must devote full time to the proposed research training and must confine clinical duties to those that are an integral part of the research training experience.

Research training may be delivered by interactive distance learning technology, if appropriate and sustainable for the LMIC participants and institutions involved. Applicants are encouraged to maximize training in the use of information technology to facilitate trainee data management and analysis, access to online scientific information and communication.

Mentorship: Each trainee should be matched a LMIC and a U.S. mentor (if appropriate) to provide scientific and career guidance. Proposed faculty mentors should have research expertise directly relevant to the proposed scientific focus of the research training program. Mentorship training may be provided for faculty mentors involved in the proposed program.

Training programs should make available structured, professional development advising activities (for example, Individual Development Plans ( https://www. nigms. nih.

gov/training/strategicplanimplementationblueprint/Pages/IndividualDevelopmentPlans. aspx ), career related practicum experiences and rotations, workshops or networking activities). Through such activities, trainees are expected to obtain a working knowledge of various career paths that will make use of the knowledge and skills gained during research training as well as the steps required to move to the next stage of their career.

Career Development Skills: Successful transition of LMIC trainees to the next research career stage should be an important consideration in designing the proposed training program.

Applicants should include training plans for strengthening skills necessary for long-term research career sustainability, such as scientific writing and presentation, grant writing, and expertise in data management, research ethics, good clinical practice, good laboratory practice, biosafety, research administration and the management of intellectual property. English as a second language training may be supported, if needed.

Short Term Training: Short term training (less than 1 month) may be proposed in addition to long term training to meet the specific objectives of the proposed program.

Short-term training should provide competitively selected LMIC trainees with a thorough exposure to the principles and skills of research methods or competencies (such as research leadership or management) that can be immediately incorporated into their research or professional development. Mentorship should be provided to ensure short term training meets this expectation.

Evaluation plans (see section below) should include specific assessment of the effectiveness of the short-term training activities proposed. Short-term training in medical care or public health program practice cannot be supported. Proposed mentored research training may take place in the U.S. or a foreign country, however, training-related research should be carried out in the LMIC as much as feasible.

All training-related research projects must be independently reviewed through rigorous scientific review procedures established by the program and obtain required approvals for human subjects and animal research from the applicant institution and if different, at the institution in which the research is conducted.

It is expected that LMIC trainees will be supported to disseminate the results of their research at scientific conferences and in peer-reviewed publications. This announcement allows support of trainees to serve as the lead investigator of an independent clinical trial; or a separate ancillary clinical trial; or to gain research experience in a clinical trial led by another investigator, as part of their research and career development.

Applications Not Responsive to the announcement: Applications that propose HIV/AIDS research training. Applications that propose research training exclusively at a U.S. or other high income country institution. Applications that propose exclusively short-term training (less than 1 month) experiences.

Applications that propose clinical care or public health program (including surveillance) training . See Section VIII. Other Information for award authorities and regulations.

Section II. Award Information Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity. Application Types Allowed The OER Glossary and the How to Apply Application Guide, provide details on these application types.

Only those application types listed here are allowed for this NOFO. Optional: Accepting applications that either propose or do not propose training in clinical trial(s). Need help determining whether you are doing a clinical trial?

Funds Available and Anticipated Number of Awards The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications. Application budgets are limited to $230,000 per year for new awards and $276,000 per year for renewal awards (total direct costs). The maximum project period allowed is 5 years.

Other Award Budget Information Stipends, Tuition, and Fees Awards may provide stipends as a subsistence allowance to help defray living expenses during research training. The cost of tuition and fees at the rate in place at U.S. or foreign institutions can be supported. Trainees may be paid a stipend comparable to their professional experience and U.S. or foreign institutional requirements.

Trainee travel for research training at a collaborating institution or to attend courses or workshops that the training program determines are necessary for the individual’s research training experience is an allowable expense for long term trainees. Awards may support trainees to present their research results at scientific conference.

Funds may be requested for lodging and per diem expenses for short term trainees required to travel significant distances to the hosting institution.

Training Related Expenses NIH will provide funds to help defray other research training expenses, such as trainee visas, trainee health insurance, research training equipment (not exceeding $5,000), trainee research supplies, laptop computers and internet access for trainees, relevant scientific journal subscriptions, publication costs, and costs for research training short courses or workshops One-time mentored research training project support for up to $20,000 for an advanced long-term trainee undertaken in his/her country may be requested.

Individuals designing, directing, and implementing the training program at U.S. and LMIC institutions may request salary and fringe benefits appropriate for the person months devoted to the program. Salaries requested may not exceed the levels commensurate with the institution's policy for similar positions and may not exceed the congressionally mandated cap.

If mentoring interactions and other activities with trainees are considered a regular part of an individual's academic duties, then mentoring and other interactions with trainees are non-reimbursable from grant funds. The salaries of administrative and clerical staff should normally be treated as indirect (F&A) costs.

Direct charging of these costs may be appropriate only if all of the following conditions are met: (1) Administrative or clerical services are integral to a project or activity; (2) Individuals involved can be specifically identified with the project or activity; (3) Such costs are explicitly included in the budget or have the prior written approval of the Federal awarding agency; and (4) The costs are not also recovered as indirect costs.

When specifically identified and justified, these expenses must be itemized in Sections A and B, as appropriate, of the R&R Budget Training consultant costs and other program-related expenses may be included in the proposed budget. Funds for one trip per year may be requested for faculty mentors to conduct well justified training activities.

Support for key personnel, faculty mentors or consultants to attend scientific meetings and conferences is not allowed. Funds should be requested for the PD(s)/PI(s) to attend an annual program networking meeting, usually held at NIH.

Indirect Costs (also known as Facilities & Administrative [F&A] Costs) are reimbursed at 8% of modified total direct costs (exclusive of tuition and fees, consortium costs in excess of $25,000, and expenditures for equipment), rather than on the basis of a negotiated rate agreement. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO. Section III.

Eligibility Information Higher Education Institutions Public/State Controlled Institutions of Higher Education Private Institutions of Higher Education Non-domestic (non-U.S.) Entities (Foreign Organizations) The sponsoring institution must assure support for the proposed program.

Appropriate institutional commitment to the program includes the provision of adequate staff, facilities, and educational resources that can contribute to the planned program.

The applicant institution must have a strong and high-quality research program in the area(s) proposed under this NOFO and must have the requisite faculty, staff, potential trainees and facilities on site to conduct the proposed institutional program documented by active research grants and recent relevant research publications.

In many cases, it is anticipated that the proposed program will complement other ongoing research training occurring at the applicant institution and that a substantial number of program faculty will have active research projects in which participating trainees may gain relevant experiences consistent with their research interests and goals.

Applications may be submitted by an eligible foreign institution in a LMIC with a collaborating U.S. institution or by an eligible U.S. institution that demonstrates ongoing collaborations with a LMIC institution named in the application. Evidence of collaboration may be documented by joint publications, research grants or previous research training activities.

Applicants are encouraged to contact the FIC Scientific/Research Contact if more than one U.S. and one LMIC institution will be proposed as training sites. LMICs are defined by the World Bank classification system (according to Gross National Income (GNI) per capita as "low-income," "lower-middle-income," and "upper-middle-income" ( http://data. worldbank.

org/about/country-classifications/country-and-lending-groups ). See Notice of Change in Country Eligibility for Fogarty International Training Grants and Country Eligibility (NOT-TW-12-011) (https://grants. nih.

gov/grants/guide/notice-files/NOT-TW-12-011. html) for definition of “ eligible LMIC" . Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.

Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.

Applicant organizations must complete and maintain the following registrations as described in the How to Apply - Application Guide , to be eligible to apply for or receive an award. All registrations must be completed prior to the application being submitted. Registration can take 6 weeks or more, so applicants should begin the registration process as soon as possible.

Failure to complete registrations in advance of a due date is not a valid reason for a late submission, please reference NIH Grants Policy Statement Section 2. 3. 9.

2 Electronically Submitted Applications for additional information. System for Award Management (SAM) – Applicants must complete and maintain an active registration, which requires renewal at least annually . The renewal process may require as much time as the initial registration.

SAM registration includes the assignment of a Commercial and Government Entity (CAGE) Code for domestic organizations which have not already been assigned a CAGE Code. NATO Commercial and Government Entity (NCAGE) Code – Foreign organizations must obtain an NCAGE code (in lieu of a CAGE code) in order to register in SAM. Unique Entity Identifier (UEI)- A UEI is issued as part of the SAM.

gov registration process. The same UEI must be used for all registrations, as well as on the grant application. eRA Commons - Once the unique organization identifier is established, organizations can register with eRA Commons in tandem with completing their Grants.

gov registration; all registrations must be in place by time of submission. eRA Commons requires organizations to identify at least one Signing Official (SO) and at least one Program Director/Principal Investigator (PD/PI) account in order to submit an application. Grants.

gov – Applicants must have an active SAM registration in order to complete the Grants. gov registration. Program Directors/Principal Investigators (PD(s)/PI(s)) All PD(s)/PI(s) must have an eRA Commons account.

PD(s)/PI(s) should work with their organizational officials to either create a new account or to affiliate their existing account with the applicant organization in eRA Commons. If the PD/PI is also the organizational Signing Official, they must have two distinct eRA Commons accounts, one for each role. Obtaining an eRA Commons account can take up to 2 weeks.

Eligible Individuals (Program Director/Principal Investigator) Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research training program as the Training Program Director/Principal Investigator (Training PD/PI) is invited to work with their organization and collaborators to develop an application for support.

For institutions/organizations proposing multiple PDs/PIs, visit the Multiple Program Director/Principal Investigator Policy and submission details in the Senior/Key Person Profile (Expanded) Component of the How to Apply - Application Guide .

The PD/PI should be an established investigator in the scientific area in which the application is targeted and capable of providing both administrative and scientific leadership to the development and implementation of the proposed program.

The PD/PI will be responsible for overseeing the process for the selection of trainees to the research training program, and for the overall direction, management, administration, and evaluation of the program. The PD/PI will be expected to monitor and assess the program and submit all documents and reports as required.

The PD/PI has responsibility for the day to day administration of the program and is responsible for appointing members of the Advisory Committee and using their recommendations to determine the appropriate allotment of funds. Collaborator Requirements: Proposed research training programs should be based on equitable and trusted collaboration.

The PD/PI should have research and research training experience in the LMIC which is the focus of the application. PD/PIs proposed by non-U.S. institutions must be permanent residents of eligible LMICs (to be verified by the applicant institution).

LMIC applicants must identify at least one U.S. scientist and U.S. applicants must identify at least one LMIC scientist with expertise in the infectious disease focus area of the proposed research training program from the proposed collaborating U.S./LMIC institution as the main collaborator for coordinating training program activities at that site.

Due to the collaborative nature of this program, applicants are encouraged to designate the main collaborator who meets the research grant eligibility requirement as a Multiple PD/PI.

Research Grant Requirement: Each PD/PI must be designated as the PD/PI of at least one research award that is directly relevant to the scientific focus of the research training proposed and with at least 18 months of support remaining at the time of submission of the application. This NOFO does not require cost sharing as defined in the NIH Grants Policy Statement Section 1. 2 Definition of Terms .

3. Additional Information on Eligibility Applicant organizations may submit more than one application, provided that each application is programmatically distinct. NIH will not accept duplicate or highly overlapping applications under review at the same time per NIH Grants Policy Statement Section 2.

3. 7. 4 Submission of Resubmission Application .

This means that the NIH will not accept: A new (A0) application that is submitted before issuance of the summary statement from the review of an overlapping new (A0) or resubmission (A1) application. A resubmission (A1) application that is submitted before issuance of the summary statement from the review of the previous new (A0) application.

An application that has substantial overlap with another application pending appeal of initial peer review (see NIH Grants Policy Statement 2. 3. 9.

4 Similar, Essentially Identical, or Identical Applications ) Program faculty should have strong records as researchers, including recent publications and successful competition for research support in the area of the proposed research training program. Program faculty should also have a record of research training, including successful, former trainees who have established productive careers.

Faculty mentors should have research and/or research training experience in the LMIC that is the focus of the application. Programs are encouraged to build a broadly diverse team of preceptors/mentors that includes, for example, faculty at different career stages (i.e., junior as well as senior faculty).

Only individuals who are citizens of LMICs (defined by the World Bank classification system) are eligible for research training support or other training activities (as verified by the PD(s)/PI(s)). Individuals who have dual citizenship or permanent residency in the U.S., other high-income countries or ineligible countries described above are not eligible for support.

All long term trainees (more than 1 month) are required to pursue their research training full time, normally defined as 40 hours per week, or as specified by the sponsoring institution in accordance with its own policies.

Research training may be offered to a wide range of scientists, including laboratory scientists, social scientists, clinicians and other health professionals, as well as technical and administrative staff in order to fill research capacity gaps at the collaborating LMIC institution.

Short Term Training: Short term training (less than 1 month) may be proposed in addition to long term training to meet the specific objectives of the proposed program.

Short-term training should provide competitively selected LMIC trainees with a thorough exposure to the principles and skills of research methods or competencies (such as research leadership or management) that can be immediately incorporated into their research or professional development. Mentorship should be provided to ensure short term training meets this expectation.

Evaluation plans (see section below) should include specific assessment of the effectiveness of the short-term training activities proposed. Short-term training in medical care or public health program practice cannot be supported. Section IV.

Application and Submission Information 1. Requesting an Application Package The application forms package specific to this opportunity must be accessed through ASSIST, Grants. gov Workspace or an institutional system-to-system solution.

Links to apply using ASSIST or Grants. gov Workspace are available in Part 1 of this NOFO. See your administrative office for instructions if you plan to use an institutional system-to-system solution.

2. Content and Form of Application Submission It is critical that applicants follow the Training (T) Instructions in the How to Apply - Application Guide except where instructed in this Notice of Funding Opportunity to do otherwise. Conformance to the requirements in the How to Apply - Application Guide is required and strictly enforced.

Applications that are out of compliance with these instructions may be delayed or not accepted for review. Although a letter of intent is not required, is not binding, and does not enter into the review of a subsequent application, the information that it contains allows IC staff to estimate the potential review workload and plan the review. By the date listed in Part 1.

Overview Information, prospective applicants are asked to submit a letter of intent that includes the following information: Descriptive title of proposed activity Name(s), address(es), and telephone number(s) of the PD(s)/PI(s) Names of other key personnel Participating institution(s) Number and title of this funding opportunity The letter of intent should be sent to: Email (preferred): [email protected] All page limitations described in the How to Apply - Application Guide and the Table of Page Limits must be followed.

Instructions for Application Submission The following section supplements the instructions found in