Grand Challenges Africa Climate and Health Initiative

Grand Challenges Africa Climate and Health Initiative is sponsored by Grand Challenges Canada and the Science for Africa Foundation. This initiative focuses on locally led innovations that help health workers, communities, and health systems anticipate and adapt to climate-related health threats, specifically reducing health harms from mosquito-borne infections, extreme heat, and poor air quality.

Funding Opportunity: Nexa - Grand Challenges Canada About us Learn more about Grand Challenges Canada What we do We fund and support innovations that save and improve lives Impact See how our investments are transforming lives and driving global change Partner with us Partner with us to fund bold ideas and scale impact Learn more about Grand Challenges Canada Our vision Our vision to build a world where innovation helps everyone thrive Our approach Learn more about how Grand Challenges Canada invests in bold ideas for big impact Grand Challenges model Overcoming barriers through innovation Leadership & team Meet the people driving strategy, partnerships and impact Work with us Join our team and help drive innovation that changes lives Accountability Our audited financials, policies, and commitment to transparency.

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Nexa Nexa is a global climate × health innovation initiative led by Grand Challenges Canada and the Science for Africa Foundation, together with a global consortium of partners investing in bold, locally led solutions that help health systems anticipate and respond to climate-driven health threats.

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Innovator resources Resources, policies and helpful documents for GCC-supported innovators Funding Opportunity: Nexa Funding Opportunity: Nexa We seek bold climate and health ideas in Africa, Latin America, and the Caribbean. Nexa is a climate and health initiative co-led by Grand Challenges Canada and the Science for Africa Foundation , in collaboration with a global consortium of partners and funders.

We are investing in bold, innovative solutions across Africa, Latin America, and the Caribbean that enable local health actors to turn climate-driven health risk signals into timely health service delivery action, reducing health harms from mosquito-borne infections, extreme heat, and poor air quality. Intake for Proof of Concept applications closed on July 22, 2026.

The Transition to Scale intake deadline was extended on July 22, 2026, moving the closing date to August 12, 2026.

Learn more about this funding opportunity Applications must directly address at least one of the following areas of focus: Climate-informed early warning and monitoring systems: Innovations that allow health actors to anticipate and respond to the impacts of heat, poor air quality, and/or changing mosquito ecology (resulting in the accelerated spread of malaria and dengue infections).

Climate-responsive patient care delivery: Innovations that strengthen local response to mosquito-borne infection harms, and/or the health impacts of heat and poor air quality. What are we investing in? Transition to Scale innovations: meaning approaches that have already been tested, proven to be effective, and are now ready to be implemented more widely.

For more details on how Nexa defines Transition to Scale, please refer to this helpful guide: Our Investment Approach . We are no longer accepting applications for Proof-of-Concept innovations. What is the funding amount?

Transition to Scale funding amounts will range between approximately $250,000 – $2,000,000 USD per innovation at the Nexa partners’ discretion, depending on the maturity of the innovation. We are no longer accepting applications for Proof-of-Concept innovations.

For Transition to Scale funding: Applicant organizations can be incorporated or equivalent in any country but must implement in eligible countries in Africa, Latin America, or the Caribbean. See the complete list of eligible countries in Appendix B of the Funding Opportunity. We are no longer accepting applications for Proof-of-Concept innovations.

Applications must be submitted via Grand Challenges Canada’s online portal (Fluxx) . We will not accept applications submitted via any other channel. For more information on how to submit an application, see our Guidance on How to Apply .

Intake for Proof of Concept applications closed on July 22, 2026. The Transition to Scale intake deadline was extended on July 22, 2026, moving the closing date to August 12, 2026. Please read all of the eligibility criteria and competition details in the full Funding Opportunity document before applying.

For more information about Nexa, please visit www. nexaclimate.

org For questions related to the content of this funding, please visit the Apply for Funding page on our website for: More information on Nexa’s investment approach via Grand Challenges Canada’s helpful guide: Our investment approach For anything not addressed through these resources, the Funding Opportunity document, or the information session, reach out to OpenCompetitions@grandchallenges.

ca Nexa Funding Opportunity – English Nexa Funding Opportunity – French Proof-of-Concept Application Questions – English Transition-to-Scale Application Questions – English Proof-of-Concept Application Questions – French Transition-to-Scale Application Questions – French Information Session Recording