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Find similar grantsGrants for Early-Stage Rare Disease Research is sponsored by Michigan State Agencies. This grant presents substantial opportunities for eligible applicants aiming to advance treatments and therapies for rare diseases in Michigan. It targets entities engaged in scientific research and development.
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Skip to in this section menu Medical Products for Rare Diseases and Conditions Grant Programs to Support Development of Medical Products for Rare Diseases Grant Programs to Support Development of Medical Products for Rare Diseases Clinical Studies of Orphan Products Addressing Unmet Needs of Rare Diseases (R01) Receipt Dates: October 21, 2025; October 20, 2026; October 19, 2027 (for new applications and resubmissions) FOA Number: RFA-FD-25-020 Funding Opportunity Purpose: The purpose of this Notice of Funding Opportunity (NOFO) is to fund clinical trials of products evaluating efficacy and/or safety in support of a new indication or change in labeling to address unmet needs in rare diseases or conditions.
Additionally, through the funding of collaborative, efficient, and/or innovative clinical trials, FDA expects to increase the number of approved treatments for rare diseases and exert a broad and positive impact on rare disease drug development. Learn more about this program: Clinical Trials Grants Program .
Efficient and Innovative Natural History Studies Addressing Unmet Needs in Rare Diseases Receipt Dates: February 10, 2026; February 8, 2028 (for new applications and resubmissions) FOA Number: RFA-FD-25-017 Funding Opportunity Purpose: The purpose of this notice of funding opportunity (NOFO) is to support efficient and innovative natural history studies that advance medical product development in rare diseases/conditions with unmet needs.
Through the support of natural history studies with high quality and interpretable data elements, FDA expects to address critical knowledge gaps, remove major barriers to progress in the field, exert a significant and broad impact on a specific rare disease or multiple rare diseases with similar pathophysiology, and facilitate rare disease product development. Learn more about this program: Natural History Studies Grant Program .
Rare Neurodegenerative Disease Grants Program Opportunities Clinical Trials Addressing Unmet Needs of Rare Neurodegenerative Diseases (R01) Clinical Trials Required Receipt Dates: October 21, 2025 FOA Number: RFA-FD-25-001 Funding Opportunity Purpose: The purpose of this notice of funding opportunity (NOFO) is to fund clinical trials of products evaluating efficacy and/or safety in support of a new indication or change in labeling to address unmet needs in rare neurodegenerative diseases for children and adults.
Through the support of collaborative, efficient and innovative clinical trials, FDA hopes to exert a broad and positive impact by increasing the number of approved medical products for rare neurodegenerative diseases. See instructions and helpful hints (PDF) for applying for rare neurodegenerative disease grants. Learn more about this program: Rare Neurodegenerative Disease Grants Program .
According to the current listing, eligibility includes: Eligible applicants aiming to advance treatments and therapies for rare diseases in Michigan, targeting entities engaged in scientific research and development. Confirm the full requirements in the official notice before applying.
Grants for Early-Stage Rare Disease Research is funded by Michigan State Agencies. Verify program details on the funder's official page before applying.
This opportunity targets applicants in Michigan. If your organization operates elsewhere, check the official notice for location requirements.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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