Health Data Science and AI Research

Health Data Science and AI Research is sponsored by National Institute of Standards and Technology (NIST). Promotes research in health data science and AI to enhance health care standards.

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coli (STEC) Researching Ebola in Africa Information for Researchers Information for Researchers Why Food Allergy is a Priority for NIAID Characterizing Food Allergy & Addressing Related Disorders Information for Researchers Diagnosis & Management Guidelines Disease-Specific Research Information for Researchers Genomics & Advanced Technologies Pathogen-Based Initiatives Information for Researchers Information for Researchers Group A Streptococcal Infections Disease-Specific Research Information for Researchers Overview of the Immune System Features of an Immune Response Information for Researchers Information for Researchers Leprosy (Hansen's Disease) How NIAID is Addressing Lyme Disease Information for Researchers Parasite, Mosquito & Human Host Prevention, Treatment & Control Strategies Strategic Partnerships & Research Capacity Information for Researchers Information for Researchers Neglected Tropical Diseases Information for Researchers Translational & Clinical Research Cross-cutting Preparedness Molecular & Genetic Research Primary Immune Deficiency Diseases (PIDDs) Information for Researchers Animal Prion Diseases and Humans Information for Researchers Respiratory Syncytial Virus (RSV) Schistosomiasis (Bilharzia) Research in Endemic Regions Sexually Transmitted Infections (STIs) NIAID's Research Approach Information for Researchers Disease-Specific Research Information for Researchers Information for Researchers Disease-Specific Vaccines Information for Researchers Translational & Clinical Research Information for Researchers Biology, Genetics & Clinical Research NIAID's Approach to Women's Health Research Sex-Specific Health Challenges Facing Women Biennial Report (FY 2019-2020) Information for Researchers Why NIAID Is Researching Zika Virus Information for Researchers Find a Funding Opportunity Opportunities & Announcements NIAID Research Priorities Plan Your Budget & Personnel Additional Application Elements Research with Special Considerations After You Submit an Application Funding Policies and Considerations Understand the Review Process Respond to Pre-Award Requests Negotiation & Initial Award Become a Healthy Volunteer Participant's Guide to Clinical Trials HIV and Emerging Infectious Diseases Laboratory of Infectious Diseases Primary Immune Deficiency Clinic Vaccine Research Center Clinical Studies Fill Out the Volunteer Form Q&A: Vaccine Clinical Studies Vaccine Clinical Studies Safeguards Clinical Trial Publications NIAID-Funded Research News Division of Allergy, Immunology, and Transplantation Division of Microbiology and Infectious Diseases Division of Extramural Activities Division of Clinical Research Division of Intramural Research Dr. Joseph J.

Kinyoun: Father of the NIH Dr. Joseph Kinyoun The Indispensable Forgotten Man Dr. Joseph Kinyoun: Selected Bibliography NIAID 60th Anniversary Timeline Research Training at NIAID Campuses Grant Programs that NIAID Funds AIDS Research Advisory Committee AIDS Vaccine Research Subcommittee Board of Scientific Counselors Members Advisory and Peer Review Committees Autoimmune Diseases Committee Website Policies and Notices External Link Icon and Disclaimers Freedom of Information Act (FOIA) Voluntarily Submitted Information Center for Systems Modeling Current Fellows and Alumni Blueprint to Connect Data Data Ecosystem Discovery Portal Data Science Across NIAID Office of Data Science and Emerging Technologies Stimulating Access to Research in Residency (StARR) (R38 Independent Clinical Trial Not Allowed) The overall goal of the Stimulating Access to Research in Residency (StARR) program is to provide resident clinicians in training with in-depth research experiences early in their careers, in order to recruit, retain and accelerate independence of a pool of clinician-investigators with both clinical Notice Number: RFA-HL-26-012 Posting Date: August 26, 2025 Expiration Date: January 11, 2028 Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science The purpose of this Notice is to announce the collaboration between the NIH and the National Science Foundation (NSF) on an interagency funding opportunity, NSF-23-614, Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science.

The Smart Health program supports innovative, high-risk/high-reward research with the promise of disruptive transformations in biomedical and public health research.

Notice Number: NOT-OD-23-165 Posting Date: August 28, 2023 Data Science Highlighted Topics Computational Modeling of Complex Processes Across Biological Scales This topic encourages innovative research in computational modeling of complex processes across biological scales (i.e., to develop multiscale models).

The topic seeks to build a collaborative community of researchers to improve the replicability and reproducibility of computational multiscale models, promoting their advancement and reuse.

Specific NIAID areas of interest include models that can: Elucidate biological mechanisms of infection and/or transmission of pathogens and inform the development of improved countermeasures, Define immune system regulation and responses to triggers (commensal and pathogenic organisms, preventative strategies, environment, autoantigens, transplant), Characterize trajectories of allergic or immune-mediated diseases from initiation through progression and/or resolution, including microbiome effects, and Help to meet emerging needs in response to pathogenic threats.

Enhancing Scientific Rigor, Transparency and Replicability Robust, high-quality research is rooted in scientific practices that ensure rigorous and transparent experimental design, methodology, analysis, and interpretation, which improve validity and reliability of findings. High-priority areas and example topics include: tools and methods, scientific norms, and scientific forums.

NIAID encourages applications that strengthen rigor, reproducibility, replicability, and transparency of research on immunologic, allergic, and infectious diseases. Areas of interest include: Leveraging interoperable data standards to integrate multimodal data (e.g., real-world and experimental data), with provenance and metadata on collection, processing, and variability to enable reproducibility.

Supporting benchmarking frameworks and metrics to enable reproducible analytical workflows, software, and models aligned with recognized repositories. Establishing frameworks to characterize biospecimens, including metadata to assess quality, collection conditions, and assay suitability. Supporting data and assay standardization, including benchmark development to improve measurement consistency.

Conducting studies to validate preclinical and clinical protocols in immunology and infectious diseases, reducing variability and improving cross-study reproducibility and replicability.

Advancing “Science of Science” Research to Understand and Strengthen the Biomedical Research Ecosystem NIAID Areas of interest include, but are not limited to, the following: Strategies to promote rigorous training for clinical trials Long-term approaches to enhancing research capacity and organizational structure to support long-term and impactful training program Fostering approaches to recruit and retain scientific talent at all levels of the biomedical workforce Strategies to spur research and training innovation, including through team science approach Secure long-term support for bench to bedside training and research programs Strategies to promote rigorous and reproducible research and scientific accountability and integrity in training Strengthening Biomedical Research, Promoting Trust, and Improving Health through Bioethics Research This topic aims to advance bioethics research projects that are actionable, build trust, and enable better integration of bioethical principles into biomedical and behavioral research.

Specific research areas of interest include: Return of Research Results Other Cross-cutting Issues NIAID research mission includes infectious diseases, organ transplantation, immunologic diseases and countermeasures, clinical trial design, implementation science, and projects related to public health surveillance and care delivery. Follow the website link for full details on the topic and NIAID interests, plus scientific contacts.

Research on Short-Lived and Long-Lived Plasma Cells in Humans This topic encourages applications to understand the biology of Short-Lived Plasma Cells (SLPC) and Long-Lived Plasma Cells (LLPC) through characterization of plasma cell phenotypes and function in human health and disease.

This topic encourages applications that include: Ex vivo analysis of human samples New approach methodologies (NAMs) Computational modeling of plasma cells in human health and disease NIAID Research Career Development Awards K01: Mentored Research Scientist Development Award K25: Mentored Quantitative Research Development Award Qualified applicants must have an advanced doctoral degree in a quantitative science field and must be at a postdoctoral to senior faculty level.

Additionally, they must demonstrate productivity in their field and must demonstrate intentions to expand their research such that their contributions to behavioral, biomedical, bioimaging, or bioengineering research will increase. Note that there may be restrictions based on past NIH funding - details can be found in the parent K25 notice of funding opportunity.

NIH highlighted topics represent research priorities at one or more NIH Institutes, Centers, or Offices. Researchers are encouraged to apply to relevant parent funding announcements, reach out to scientific contacts, or take other appropriate next steps outlined on the Highlighted Topics page in order to submit their related research for funding consideration. View all NIH Highlighted topics Content last reviewed on May 18, 2026