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HHS Innovation Challenge (Phase One Grant) is sponsored by U.S. Department of Health and Human Services (HHS). The HHS Innovation Challenge seeks groundbreaking approaches to preventing human trafficking among women and girls in the United States, utilizing data-driven solutions to enhance analytics and collection capabilities and create predictive models of risk for sex trafficking.
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extended-search-field-small Search * IO Programs and Initiatives * HHS Initiative on Substance Exposure in the Mother-Infant Dyad * Understanding Your Eligibility * How to Apply for Jobs at OASH * Current Job Opportunities * Future Job Opportunities * Grants & Cooperative Agreements * Advisory Committee on Blood & Tissue Safety & Availability * National Vaccine Advisory Committee * Presidential Advisory Council on Combatting Antibiotic-Resistant Bacteria * Reports & Recommendations * Timeline & Past Meetings * Federal Resources on AMR * Presidential Advisory Council on HIV/AIDS * President’s Council on Sports, Fitness & Nutrition * Secretary’s Advisory Committee on Human Research Protections * 2025 Dietary Guidelines Advisory Committee A Challenge Competition is a way for federal agencies to crowdsource and engage public innovators directly to find interesting ideas or solutions to important problems.
You can learn more about this unique opportunity on Challenge. gov. OASH Challenge Competitions are posted on Challenge. gov. The rules of each competition vary.
Be sure to read all of the rules and requirements. * ## HHS Innovation Challenge to Prevent Human Trafficking Among Women and GirlsCall for innovative and preventive solutions to human trafficking among women and girls. * ## HHS Environmental Justice Community Innovator ChallengeCommunity-driven strategies to address environmental and climate change health issues.
Phase 2 open until 06/30/2024 * Grants & Cooperative Agreements * Nondiscrimination Notice ### Office of the Assistant Secretary for Health
According to the current listing, eligibility includes: Organizations with innovative approaches to preventing human trafficking among women and girls in the United States. Confirm the full requirements in the official notice before applying.
The current listing shows up to $1.8 million total (initial $50,000 for Phase One, followed by $100,000 for eight organizations in Phase Two). Verify award ceilings, matching requirements, and allowable costs in the official notice.
HHS Innovation Challenge (Phase One Grant) is funded by U.S. Department of Health and Human Services (HHS). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Native American Language Preservation and Maintenance Program is sponsored by Administration for Native Americans (ANA), U.S. Department of Health and Human Services (HHS). This program funds projects to support assessments of the status of native languages in established communities, as well as planning, designing, restoration, and implementing of native language curriculum and education projects to support a community's language preservation goal…
Native American Language Preservation and Maintenance is sponsored by Administration for Native Americans (ANA), Administration for Children and Families (ACF), U.S. Department of Health and Human Services (HHS). This program funds projects to support assessments of the status of native languages in established communities. It also funds planning, designing, restoration, and implementing of native language curriculum and education projects to support a community's language preservation goals. Native American communities include American Indian tribes (federally-recognized and non-federally recognized), Native Hawaiians, Alaskan Natives, and Native American Pacific Islanders.
NCI Continuing Umbrella of Research Experiences (CURE) Academic Career Excellence (ACE) Award (K32) is a grant from the National Cancer Institute (NCI) that funds early postdoctoral fellows from diverse backgrounds, including underrepresented groups, to pursue research training in cancer-related fields. The K32 award supports fellows within 12 months prior to transitioning into, or within the first two years of, a postdoctoral position. The program, operated through NCI's Center to Reduce Cancer Health Disparities (CRCHD), aims to enhance the pool of qualified diverse cancer researchers. Beginning with the June 12, 2025 due date, the CURE ACE Award is available in both Independent Clinical Trial Required and Independent Clinical Trial Not Allowed versions. Eligible applicants must be U.S. citizens or permanent residents at time of award.
Innovation Grant is a grant from the Delta Dental of Arizona Foundation that funds nonprofit organizations pursuing unique, high-impact projects that improve health and wellness in Arizona communities. This two-year award supports original initiatives with measurable real-world impact, including programs serving underserved and uninsured populations through oral health education, disease prevention, and nutritional access. Projects must demonstrate the potential to make a meaningful difference in the community and stand apart from conventional approaches. Eligible applicants are Arizona-based nonprofit organizations. Awards total $100,000 per recipient over two years. The 2026 application cycle closed October 16, 2025, with recipients notified in late 2025 and funding made available shortly after.
The HHS Grants Policy Statement that took effect October 1, 2025 raised the micro-purchase threshold to $50,000, the single audit threshold to $1 million, and the de minimis indirect cost rate to 15 percent — quietly rewriting the operational rules for tens of billions of dollars in annual awards. Combined with full 2 CFR Parts 200 and 300 adoption and new MAHA-aligned program priorities, it is the biggest compliance shift for health grantees since Uniform Guidance arrived in 2013.
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