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Stage 1 closed March 17, 2026 with 52 proposals submitted. Stage 2 evaluation results expected late June 2026; grant agreements estimated by November 17, 2026. The stored deadline of 2026-10-13 does not match any listed milestone.
HORIZON-CL4-2026-02-two-stage: Development of safe and sustainable alternatives to substances of concern is sponsored by European Commission. Funds innovation actions aimed at developing safe and sustainable alternatives to substances of concern.
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HORIZON-CL4-2026-02-MAT-PROD-21-two-stage | TopicTree (by Ideal-ist) HORIZON-CL4-2026-02-MAT-PROD-21-two-stage Development of safe and sustainable alternatives to substances of concern (IA) The graph above was generated based on the following links Call text (as on F&T portal) Make safer and more sustainable alternatives to substances of concern available to the industries offering products with targeted performances and supporting their competitiveness, Speeding up the innovation cycle within a value chain important for European industry; Enhancing competitiveness of the industries by reducing regulatory and operational costs, while making supply chains more secure; Production processes, chemicals, materials and products that are inherently safer and more sustainable for a clean and autonomous economy; and Demonstrating how the safe and sustainable by design (SSbD) chemicals and materials framework can guide innovation and encourage innovators to minimise the use of substances of concern, reducing negative impacts on human health, climate and ecosystems.
The focus of this topic is on alternatives for the substitution of substances of concern (SoCs) as defined in the Ecodesign for Sustainable Product regulation[1]. The design and development of these alternatives should lead to an innovation cycle covering their (re)design, development, production processes, and integration into products in manufacturing.
The scope includes necessary developments of related processes and technologies to ensure alignment with and integration in industrial manufacturing facilitating uptake of the develop alternatives. If relevant, challenges for the adaption of existing production lines should be identified and solutions proposed.
Proposals should develop new chemical substances, innovative advanced materials or technologies to replace existing SoCs in one of the following areas: energy, mobility, construction, electronics, technical textiles as well as medical devices. Proposals should demonstrate that the proposed alternative has a clear use case, market and potential to grow.
The substitution barriers for the selected applications should be identified and effective mechanisms to maximise substitution within the targeted value chains proposed.
Proposals should demonstrate that SSbD framework[2] will be applied throughout the innovation process, showing that safety and sustainability principles are actively integrated and influence decision-making in a transparent and traceable way, and ensure that the data generated within the proposal may be shared with the Common Data Platform for Chemicals.
The new alternatives to be developed should meet the technical functions required in the specific applications while aligning their innovation process decision making with such framework. Proposals are encouraged to cooperate with relevant projects and should contribute to and cooperate with the EU Innovation and Substitution Hub(s). Proposals should allocate the necessary resources to the proposed activities.
Proposals should include a business case and exploitation strategy, as outlined in the introduction to this Destination. Proposals could consider involving the European Commission's Joint Research Centre (JRC), whose contribution could add value to the operationalisation of the SSbD framework. Activities are expected to start at TRL 5 and achieve TRL 7 by the end of the project – see General Annex B.
[1] REGULATION (EU) 2024/1781 establishing a framework for the setting of ecodesign requirements for sustainable products, Article 2: definitions, recital 27 [2] See documents defining the SSbD framework and criteria on: https://ec. europa.
eu/info/research-and-innovation/research-area/industrial-research-and-innovation/key-enabling-technologies/advanced-materials-and-chemicals_en CALL UPDATE: PROPOSAL NUMBERS Call HORIZON-CL4-2026-02-two-stage_stage 1 has closed on 17. 03. 2026.
322 proposals have been submitted. The breakdown per topic is: HORIZON-CL4-2026-02-DIGITAL-EMERGING-51-two-stage: 191 HORIZON-CL4-2026-02-DIGITAL-EMERGING-53-two-stage: 79 HORIZON-CL4-2026-02-MAT-PROD-21-two-stage: 52 Evaluation results are expected to be communicated around the 4th week of June 2026. The technical issue affecting the upload of part B to the proposal submission tool has now been resolved.
Please note that, due to a technical issue, it is currently not possible to upload part B to the proposal submission tool. Our IT service is actively working to resolve the issue shortly. We apologise for any temporary inconvenience caused.
The submission session is now available for: HORIZON-CL4-2026-02-DIGITAL-EMERGING-53-two-stage, HORIZON-CL4-2026-02-MAT-PROD-21-two-stage, HORIZON-CL4-2026-02-DIGITAL-EMERGING-51-two-stage Opening date: 2025-12-16 (6 months ago) Closing date: 2026-03-17 (3 months ago) Contribution: 6,000,000 - 7,500,000 This call topic has been appended 4 times by the EC with news. call update: proposal numbersproposal nu...
the technical issue affecting the upload... dear applicants,please note that, due to... the submission session is now available...
HORIZON-CL4-2026-02-two-stage Call topics are often grouped together in a call. Sometimes this is for a thematic reason, but often it is also for practical reasons. There are 2 other topics in this call: HORIZON-CL4-2026-02-DIGITAL-EMERGING-51-two-stage HORIZON-CL4-2026-02-DIGITAL-EMERGING-53-two-stage Showing the latest information.
Found 9 versions of this call topic in the F&T portal. Check the differences between the versions.
You must be logged in to add annotations This is just a very first implementation, better visualisation coming Horizon Europe Industry 2026 Brokerage Event This is the place to find partners for EU projects in industrial technologies and advanced manufacturing under Horizon Europe 2026 Cluster 4 Industry calls with deadlines 17 Mar 2026 (first stage of two-stage calls ) and 21 Apr 2026 ( single-stage calls ) .
Horizon Europe Cluster 4 Info Days 2026 During the Info Days, representatives of the European Commission will present the 2026 call topics in Horizon Europe Cluster 4 and answer questions from the audience. You do not need to register to attend this online event, simply follow the live stream on the day.
KETs Brokerage Event 2026 Do you want to tackle the challenges of Industry, Manufacturing & Production, Materials , Digital/AI/Robotics, Batteries and Hydrogen ? - Then use the unique opportunities of the KETs (Key Enabling Technologies) 2026 EU Brokerage Event on February 5, 2026 in Karlsruhe, Germany! Events are added by the ideal-ist NCP community and are hand-picked.
If you would like to suggest an event, please contact idealist@ffg. at . What phase of the topic timeline are we in?
This timeline contains some suggestions on what are realistic actions you should or could take at this moment. The timeline is based on the information provided by the call topic. 2025-10-16 - 8 months ago The call topics are published first in the Work Programme, which is available a while before the call opens.
By following up the Work Programme publications, you can get a headstart. 2025-12-13 - 6 months ago The call was first imported in TopicTree. 2025-12-16 - 6 months ago The call opened for submissions.
2026-03-17 - 3 months ago Deadline for submitting a project. Time to inform applicants 2026-08-17 - 1 month from now The maximum time to inform applicants (TTI) of the outcome of the evaluation is five months from the call closure date. 2026-11-17 - 4 months from now The maximum time to sign grant agreements (TTG) is three months from the date of informing applicants.
Project information comes from CORDIS (for Horizon 2020 and Horizon Europe) and will be sourced from F&T Portal (for Digital Europe projects) This call topic is part of: This section will come soon and contain the scraped information from the call document, such as the expected impact, scope, and other relevant sections. In the meantime, you can find this information in the call text section or directly on the F&T portal.
According to the current listing, eligibility includes: Open to legal entities based in EU Member States and Associated Countries. Confirm the full requirements in the official notice before applying.
The current listing shows €38,000,000. Verify award ceilings, matching requirements, and allowable costs in the official notice.
Applications for HORIZON-CL4-2026-02-two-stage: Development of safe and sustainable alternatives to substances of concern are due October 13, 2026. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
HORIZON-CL4-2026-02-two-stage: Development of safe and sustainable alternatives to substances of concern is funded by European Commission. Verify program details on the funder's official page before applying.
This listing is flagged as international in scope. Check the official notice for country-specific restrictions before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.