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Find similar grantsHub Molecules of Metabolism and Signalling – Key regulators of Life: HubMOL is sponsored by Horizon Europe. A Horizon Europe-funded doctoral network focusing on training researchers in the signaling and metabolism of hub molecules.
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Hub Molecules of Metabolism and Signalling – Key regulators of Life Doctoral training in signalling and metabolism of hub molecules Metabolic disorders put a significant burden on European healthcare systems and contribute to diseases such as neurodegeneration and cancer. These diseases are often accompanied or even caused by changes in the hub molecules of life (HubMOLs).
HubMOLs (such as nicotinamide adenine dinucleotide and coenzyme A) are small molecules with dual functionality that play critical roles in metabolism but also in signalling and gene regulation, for example through their involvement in post-translational protein modifications.
Supported by the Marie Skłodowska-Curie Actions programme, the HubMOL project will train 16 doctoral candidates in experimental, computational, and clinical methods to explore hub molecule biology and develop personalised vitamin supplementation strategies. Furthermore, the project aims to create therapies targeting metabolic and regulatory imbalances.
Show the project objective Hide the project objective Metabolic disorders are a major burden on the European population and health care systems. Moreover, metabolic perturbations contribute substantially to other pathologies such as neurodegenerative disorders and cancer. The causes of metabolic dysregulation are manifold and lead to pathological shifts, often in response to imbalanced nutrition.
Likewise, changes in metabolism affect signalling mechanisms and gene regulation, aggravating the pathology. The mechanisms of this interdependence between metabolism and signalling are still not well understood.
HubMOL will fill this knowledge gap and open new horizons by exploring the functional duality of a set of small molecules that are involved in all cellular functions - the Hub Molecules Of Life (HubMOLs) including ATP, SAM (S-adenosylmethionine) and the vitamin-derived cofactors, NAD, FAD, and CoA.
They are key components of both metabolism and signalling networks and are interconnected, for example, through their participation in posttranslational protein modifications (PTMs). The complexity of this emerging area requires interdisciplinary scientists equipped with comprehensive competences covering experimental, computational and systems biology as well as clinical medicine.
Therefore, the main HubMOL goal is to provide world-class training in these areas to 16 DCs enabling them to establish fundamentally new insights into cofactor biology and lay the ground for patient-tailored vitamin supplementation concepts.
The strategic exposure of the 16 young researchers to leading European academic institutions, companies and clinical environments combined with systematic training in entrepreneurship and transferable skills will strongly improve their employability for positions in both private and public sectors. HubMOL will impact patients and society by developing therapies for metabolic and regulatory imbalances based on hub molecule biology.
Fields of science (EuroSciVoc) CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary . medical and health sciences medical and health sciences medical and health sciences Suggest new fields of science Project’s keywords as indicated by the project coordinator.
Not to be confused with the EuroSciVoc taxonomy (Fields of science) Multi-annual funding programmes that define the EU’s priorities for research and innovation. HORIZON. 1.
2 - Marie Skłodowska-Curie Actions (MSCA) See all projects funded under this programme Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
HORIZON-MSCA-2023-DN-01-01 - MSCA Doctoral Networks 2023 See all projects funded under this topic Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
HORIZON-TMA-MSCA-DN - HORIZON TMA MSCA Doctoral Networks See all projects funded under this funding scheme Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding. See all projects funded under this call UNIVERSITETET I TROMSOE - NORGES ARKTISKE UNIVERSITET Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party.
It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants. Higher or Secondary Education Establishments Participation in EU R&I programmes HORIZON collaboration network The total costs incurred by this organisation to participate in the project, including direct and indirect costs.
This amount is a subset of the overall project budget. Sort by Net EU contribution Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party.
It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants. Higher or Secondary Education Establishments Participation in EU R&I programmes HORIZON collaboration network The total costs incurred by this organisation to participate in the project, including direct and indirect costs.
This amount is a subset of the overall project budget. Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party.
It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants. CARRETERA DE CAN RUTI CAMI DE LES ESCOLES S/N Participation in EU R&I programmes HORIZON collaboration network The total costs incurred by this organisation to participate in the project, including direct and indirect costs.
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It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants. Higher or Secondary Education Establishments Participation in EU R&I programmes HORIZON collaboration network The total costs incurred by this organisation to participate in the project, including direct and indirect costs.
This amount is a subset of the overall project budget. Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party.
It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants. Higher or Secondary Education Establishments Participation in EU R&I programmes HORIZON collaboration network The total costs incurred by this organisation to participate in the project, including direct and indirect costs.
This amount is a subset of the overall project budget. Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party.
It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants. Higher or Secondary Education Establishments Participation in EU R&I programmes HORIZON collaboration network The total costs incurred by this organisation to participate in the project, including direct and indirect costs.
This amount is a subset of the overall project budget. Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party.
It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants. Higher or Secondary Education Establishments Participation in EU R&I programmes HORIZON collaboration network The total costs incurred by this organisation to participate in the project, including direct and indirect costs.
This amount is a subset of the overall project budget. Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party.
It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants. Participation in EU R&I programmes HORIZON collaboration network The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.
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The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants. The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Private for-profit entities (excluding Higher or Secondary Education Establishments) Participation in EU R&I programmes HORIZON collaboration network The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget. Net EU financial contribution.
The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants. 82152 PLANEGG- MARTINSRIED The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
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Sort by Net EU contribution Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party.
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Beilstein-Institut zur Förderung der Chemischen Wissenschaften Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
Frankfurt am Main, Kreisfreie Stadt Participation in EU R&I programmes HORIZON collaboration network The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget. Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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Hietzinger Hauptstrasse 145 Private for-profit entities (excluding Higher or Secondary Education Establishments) Participation in EU R&I programmes HORIZON collaboration network The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party.
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GESCHWISTER SCHOLL PLATZ 1 München, Kreisfreie Stadt Higher or Secondary Education Establishments Participation in EU R&I programmes HORIZON collaboration network The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget. Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.
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EDIF A CAMPUS DE LA UAB BELLATERRA CERDANYOLA V 08193 Cerdanyola Del Valles Higher or Secondary Education Establishments Participation in EU R&I programmes HORIZON collaboration network The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.
Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party.
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This amount is a subset of the overall project budget. Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement. RIJKSUNIVERSITEIT GRONINGEN Net EU financial contribution.
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Higher or Secondary Education Establishments Participation in EU R&I programmes HORIZON collaboration network The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget. Download Download the content of the page Last update: 30 April 2026 Permalink: https://cordis.
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According to the current listing, eligibility includes: Nonprofit research institutions in EU member states. Confirm the full requirements in the official notice before applying.
The current listing shows €4,181,040. Verify award ceilings, matching requirements, and allowable costs in the official notice.
Hub Molecules of Metabolism and Signalling – Key regulators of Life: HubMOL is funded by Horizon Europe. Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Partners Advisory Board Funding grants is sponsored by Masonic Cancer Alliance (MCA) and The University of Kansas Cancer Center. Grants to researchers at Children's Mercy Kansas City for projects focused on pediatric cancer research, including immunotherapy, drug metabolism in specific patient populations, novel small molecules for leukemia, and therapeutic strategies for diffuse midline glioma.
Arthritis, Musculoskeletal and Skin Diseases Research is sponsored by Department of Health And Human Services. The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) mission is to support research into the causes, treatment, and prevention of arthritis and musculoskeletal and skin diseases; training of basic and clinical scientists to carry out this research; and dissemination of information on research progress in these diseases. The Extramural Program promotes and supports basic, translational, and clinical studies of Systemic Rheumatic and Autoimmune Diseases, Skin Biology and Diseases, Bone Biology and Diseases, Muscle Biology and Diseases, and Joint Biology and Diseases and Orthopaedics. NIAMS Systemic Rheumatic and Autoimmune Diseases programs address basic, translational, and clinical research, including clinical trials and observational and mechanistic studies, focused on immune-mediated arthritis and autoimmune-related acute and chronic disorders in adults and children. NIAMS Skin Biology and Diseases programs support basic, translational, and clinical research in skin, including both common and rare skin diseases. These programs include investigations of the basic molecular, cellular, and developmental biology of skin, as well as studies of skin as an immune, sensory, endocrine, and metabolic organ. NIAMS Bone Biology and Diseases programs support research on the control of bone formation, resorption, and mineralization as well as the effects of signaling molecules on bone cells. They support clinical studies of interventions to prevent fractures associated with osteoporosis and research into less common bone diseases. NIAMS Muscle Biology and Diseases programs encourage research on muscle developmental biology, growth, maintenance, and hypertrophy; physiology of contraction; structural biology of the contractile apparatus; disease mechanisms; biomarkers and outcome measures; and development and clinical testing of therapies for conditions including the muscular dystrophies. NIAMS Joint Biology, Diseases, and Orthopaedics programs support a broad spectrum of research centered on the interplay among the body’s muscles, bones, and connective tissues. They encourage tissue engineering and regenerative medicine research, molecular biology, imaging, and clinical research, and the treatment and prevention of orthopaedic conditions. NIAMS participates in the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs. The SBIR program is intended to increase private sector commercialization of innovations derived from Federal research and development; to increase small business participation in Federal research and development; and to foster and encourage participation of socially and economically disadvantaged small business concerns and women-owned small business concerns in technological innovation. The STTR program is intended to stimulate and foster scientific and technological innovation through cooperative research and development carried out between small business concerns and research institutions; to foster technology transfer between small business concerns and research institutions; to increase private sector commercialization of innovations derived from Federal research and development; and to foster and encourage participation of socially and economically disadvantaged small business concerns and women-owned small business concerns in technological innovation. This listing is currently active. Program number: 93.846. Last updated on 2025-03-05.
Arthritis, Musculoskeletal and Skin Diseases Research - Training Individual (TR) is sponsored by Department of Health And Human Services. The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) mission is to support research into the causes, treatment, and prevention of arthritis and musculoskeletal and skin diseases; training of basic and clinical scientists to carry out this research; and dissemination of information on research progress in these diseases. The Extramural Program promotes and supports basic, translational, and clinical studies of Systemic Rheumatic and Autoimmune Diseases, Skin Biology and Diseases, Bone Biology and Diseases, Muscle Biology and Diseases, and Joint Biology and Diseases and Orthopaedics. NIAMS Systemic Rheumatic and Autoimmune Diseases programs address basic, translational, and clinical research, including clinical trials and observational and mechanistic studies, focused on immune-mediated arthritis and autoimmune-related acute and chronic disorders in adults and children. NIAMS Skin Biology and Diseases programs support basic, translational, and clinical research in skin, including both common and rare skin diseases. These programs include investigations of the basic molecular, cellular, and developmental biology of skin, as well as studies of skin as an immune, sensory, endocrine, and metabolic organ. NIAMS Bone Biology and Diseases programs support research on the control of bone formation, resorption, and mineralization as well as the effects of signaling molecules on bone cells. They support clinical studies of interventions to prevent fractures associated with osteoporosis and research into less common bone diseases. NIAMS Muscle Biology and Diseases programs encourage research on muscle developmental biology, growth, maintenance, and hypertrophy; physiology of contraction; structural biology of the contractile apparatus; disease mechanisms; biomarkers and outcome measures; and development and clinical testing of therapies for conditions including the muscular dystrophies. NIAMS Joint Biology, Diseases, and Orthopaedics programs support a broad spectrum of research centered on the interplay among the body’s muscles, bones, and connective tissues. They encourage tissue engineering and regenerative medicine research, molecular biology, imaging, and clinical research, and the treatment and prevention of orthopaedic conditions. This listing is currently active. Program number: 93.AR3. Last updated on 2026-01-28.
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