Impact and Boost Grants (Martin County)

Boosting biorefinery competitiveness through biotech is sponsored by European Commission — Horizon Europe. Expected Outcome: Successful proposals will contribute to the implementation of the EU initiative on Biotechnology and Biomanufacturing, the EU Life Sciences Strategy, the updated EU Bioeconomy Strategy, the EU Biotechnology Act, the Clean Industrial Deal, the European Chemical Industry Action Plan and the upcoming EU Circular Economy Act. Projects results are expected to contribute to the following expected outcomes: Full industrial scale biorefinery and related value chain(s) for the sustainable production of bio-based products using biotech as a key enabling technology. Availability of bio-based products meeting market and technical performance requirements as relevant for their respective application areas. Improvement of sustainability, circularity and resource efficiency compared to relevant benchmark(s). Contribution to increasing the EU’s strategic autonomy, resilience and competitiveness. Scope: Biorefineries integrating biotechnologies, underpinned by sustainably sourced bio-based feedstock, have a huge potential to transform the EU manufacturing landscape, spurring socio-economic growth, fostering job creation and contributing to defossilisation of the EU economy. Europe is strong in life sciences including industrial biotechnology. However, research results often struggle to be deployed to the market; in most cases, scale-up needs de-risking and requires overcoming challenges in large-scale process and reactor design, cell productivity, efficient use of feedstock, operative condition stability, reactor sterility and efficient integration of downstream operations among others. Proposals under this topic should: Demonstrate (at TRL 8) a sustainable and robust biomanufacturing route to obtain bio-based product(s). The proposal should focus on processes in which biotechnology is the key enabling technology; the integration of (upstream and/or downstream) supporting unit operations based on technologies other than biotechnology is in scope. Products in scope include chemicals, intermediates, polymers, ingredients and enzymes. Food and feed ingredients as main application are out of scope. Optimisation of selected cells, enzymes and/or microorganisms is also in scope provided that the starting TRL is at least 6. Demonstrate (at TRL 8) the further conversion or use of the obtained biorefinery product(s) into at least one end-product driving the business case; validate it (TRL 6 and above) in relevant market applications. Additional end-product(s) with high prospective market potential can be targeted, reaching at least TRL 6. In addition to the specific requirements applicable for the type of action, as described in section 2.2.3.1 of the CBE JU Annual Work Programme 2026 [1] , proposals under this topic should: As part of the multi-actor approach (MAA), ensure adequate involvement of all key actors in the value chains relevant for this topic and across the sustainable circular bio-based system, including feedstock providers, policymakers and end users. Address compliance with EU regulatory frameworks as relevant for targeted products and applications, identify potential gaps and provide recommendations to overcome them. Perform a risk assessment on impacts, potentially deriving from the use of biotechnology, on human and ecosystem safety and identify adequate mitigation measures. Assess the adequacy of policy and regulatory means to manage these risks and provide recommendations to overcome potential identified bottlenecks. Include a task to apply the SSbD framework, developed by the European Commission, for the assessment of the production process of targeted biorefinery product(s) as well as the chosen derived end product(s). For more information on the SSbD framework and criteria, refer to Safe and sustainable by design . Seek complementarities and avoid overlaps with past and ongoing R&I projects addressing similar challenges, including those funded by BBI JU/CBE JU and under Horizon 2020/Horizon Europe (under Cl Programme areas: Global Challenges and European Industrial Competitiveness, Food, Bioeconomy Natural Resources, Agriculture and Environment, Bio-based Innovation Systems in the EU Bioeconomy, Horizon Europe (HORIZON) Keywords: Applied and industrial chemistry, Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation, Industrial bioengineering, Industrial biotechnology, bio-based feedstock, bio-based products, bio-conversion, bioreactors, biorefineries, downstream technologies, safe and sustainable by design, STEP-Biotech

Advancing the European bio-based innovation enabled by biotechnology and biomanufacturing concepts is sponsored by European Commission — Horizon Europe. Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: significant advance in the development of innovation in biotechnology, life sciences and/or biomanufacturing concepts, preparing future deployment of bio-based and bio-inspired processes, products and materials, as a basis for sustainable, fair, safe and circular value chains, contributing to decarbonisation, industrial competitiveness and the strategic autonomy of the EU and Associated Countries; improved environmental sustainability of the developed innovative bio-based solutions, with positive and quantifiable impact on climate and biodiversity, and circularity of the European bioeconomy via enhanced resource efficiency, including of biological feedstocks, water and energy, integrating bio-based sector to minimize and remediate waste production. Scope: Actions funded under this topic are relevant to the EU policies related to the European Commission communication on ‘Building the future with nature: Boosting Biotechnology and Biomanufacturing in the EU’, the Life Sciences Strategy, the upcoming EU Biotech Act, and Circular Economy Act, the EU strategy on research and technology infrastructure, the Clean Industrial Deal and the policies related to the digital transition (e.g. AI Act, etc.). It also contributes to the Start-ups and Scale-ups Strategy. Proposals should address the following activities: identify, select and develop further promising selected key technologies underpinning the bio-based innovation/industry, in particular R&D on synthetic/molecular biology, gene editing, metabolic engineering, microbiome [1] , and/or biofoundry approaches, covering all applications aiming at clean growth and environmental solutions. Advancing towards validation at a pilot-scale is encouraged, to enable future exploitation. The applications in health biotechnology, as well as the biofuel/bioenergy area are excluded, to avoid overlaps with Horizon Europe Clusters 1 and 5, respectively; ensure the integration of digital technologies (e.g. AI/Machine Learning, bioinformatics); advance the convergence of biotech and life sciences developed under the first point with Nature-based Solutions, e.g. for environmental applications, carbon sequestration [2] , biodiversity protection/enhancement, aligned with (bio-)circular economy principles (e.g. cascading biomass use), ensuring the environmental fate and sustainability is considered quantitatively at the earliest stage and ensuring safety to human health and environment is addressed and guaranteed; develop recommendations for policy makers and industrial actors, taking into account the available scientifically sound assessment of risks and benefits of the developed solutions. Proposals should involve SMEs – both as project beneficiaries and as external actors – and offer opportunities to newcomers (to Horizon Europe Cluster 6). Proposals should also engage with the civil society stakeholders such as NGOs and consumer organisations to seek stakeholder involvement and acceptance, thus advancing scale-up and facilitating future market uptake. Proposals need to ensure compliance with the ‘Do no significant harm’ (DNSH) principle. Proposals are encouraged to consider, where relevant, the data, expertise and services offered by European research infrastructures [3] , such as EMSO ERIC, EU-OPENSCREEN, ELIXIR, EMBRC ERIC, IBISBA. Efforts should be made to ensure that the data produced in the context of this topic is FAIR (Findable, Accessible, Interoperable and Re-usable). Cooperation with the parallel projects funded under topic HORIZON-CL6-2026-01-CIRCBIO-10: Bio-based innovation in society: supporting the sustainable way of living is encouraged, to benefit from synergies and avoid overlaps. Similarly, activities should benefit from synergies and avoid overlaps with ongoing projects, e.g. funded under the topic HORIZON-CL6-2022-CIRCBIO-02-05-two-stage: Life sciences and their convergence wi Programme areas: Horizon Europe (HORIZON), Global Challenges and European Industrial Competitiveness, Food, Bioeconomy Natural Resources, Agriculture and Environment, Bio-based Innovation Systems in the EU Bioeconomy Keywords: Agricultural biotechnology, Bio-based products (products that are manufactured using biological material as feedstock) bio-based materials, bio-based plastics, biofuels, bio-based and bio-derived bulk and fine chemicals, bio-based and bio-derived novel materials, Biochemistry and molecular biology, Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation, Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials, Cell biology and molecular transport mechanisms, Cell biology, Microbiology, DNA synthesis, modification, repair, recombination, degradation, Environmental biotechnology, Environmental biotechnology related ethics, Environmental biotechnology, bioremediation, biodegradation, General biochemistry and metabolism, Industrial biotechnology, Natural resources exploration and exploitation, Other biological topics, Plant sciences, botany, Proteomics, RNA synthesis, processing, modification and degradation, Social innovation, Social sciences, interdisciplinary, bio-based, bio-product, bioeconomy, biofoundry, bioinformatics, biomanufacturing, bioproduct, biotechnology, environmental biotechnology, gene editing, industrial biotechnology, life sciences, microbiome, synthetic biology

Demonstrating and deploying innovative collection, sorting-for-reuse and repair systems for textiles at city/region level (Circular Cities and Regions Initiative topic) is sponsored by European Commission — Horizon Europe. Expected Outcome: Project results are expected to contribute to all of the following expected outcomes: local/regional authorities and their operators adopt optimised collection and sorting systems of municipal waste that prioritise textile reuse and repair; social economy entities and society at large benefit from favourable conditions for reuse and repair practices which enable product lifetime prolongation and stimulate second-hand markets; citizens have access to better information, leading to greater awareness and public acceptance, and stimulating behavioural change towards sustainable consumption; innovative circular textile methodologies, practices and solutions are made available to enable large-scale replication and upscaling in European cities and regions; businesses are stimulated to advance repair strategies and circular business models while creating new jobs. Scope: This topic supports the implementation of the European Commission’s Circular Cities and Regions Initiative (CCRI). It is part of a series of CCRI-related topics funded under Horizon Europe with the aim of accelerating place-based innovation, boosting skills and capacities as well as supporting the implementation of solutions for a circular systemic transition at city/region level. The implementation of circular systemic solutions reduces environmental impacts and contribute to the preservation of biodiversity, by decreasing the extraction of primary raw materials and minimizing waste generation. Proposals should: develop, test and validate innovative solutions that accelerate the adoption of textile reuse and repair practices by local/regional authorities and their operators (e.g. public collection points, retailer take-back schemes); involve citizens, local (e.g. upcycling) businesses and social enterprises in the development and implementation of local repair & reuse strategies and practices; improve data captured on local textile waste flows and ensure transparency and traceability across the supply chain; develop solutions for sorting, and preparing for re-use, including digital solutions (in view of the implementation of digital product passport) and AI to enable repair and affordable pricing of repaired clothes and to stimulate reuse of textiles, particularly apparels; incentivise manufacturers to provide spare parts to enhance reuse and reparability (e.g. linen for a coat, extra buttons, zippers, etc.) and to provide extended guarantee. develop actionable recommendations for replication in other European cities and regions. Proposals must use the multi-actor approach and take into account a gender sensitive and inclusive approach. Collaboration between retailers/manufacturers and small repair business and social enterprises is encouraged. Proposals should seek to contribute to the goals and cooperate with the services of the European Commission’s Circular Cities and Regions Initiative (CCRI) and in particular with the CCRI Coordination and Support Office. Joint activities with other CCRI-related projects and clustering with other related projects is strongly encouraged. Proposals should also evaluate the feasibility, effectiveness and impact of the demonstrated solutions using robust evaluation methods (including lifecycle assessments such as product environmental footprint, where relevant) and present data and evidence about the economic, environmental and social costs and benefits of the developed solutions. The topic requires the effective contribution of SSH disciplines and the involvement of SSH experts, institutions as well as the inclusion of relevant SSH expertise, in order to produce meaningful and significant effects enhancing the societal impact of the related research activities. The topic supports the European Green Deal, the Ecodesign for Sustainable Products Regulation and its working plan, the upcoming Circular Economy Act and contributes to Europe’s efforts to develop a single market for sustainable products. It also contr Programme areas: Horizon Europe (HORIZON), Global Challenges and European Industrial Competitiveness, Food, Bioeconomy Natural Resources, Agriculture and Environment, Circular Systems Keywords: Business model innovation, Circular economy, Climate change mitigation, Competitiveness, innovation, research and development, Design innovation, Ecodesign, Life Cycle Analysis, Environment, Environment, Pollution & Climate, Environment, resources and sustainability, Environmental change and society, Environmental protection, Greenhouse gases, Inclusion, Industrial innovation policy, Industrial sectoral change, Innovation policy, Innovation strategies, Innovation systems, Knowledge and Technology transfer, Knowledge transfer, Natural resources and environmental economics, New business opportunities, New industrial value chains, Organizational innovation, Polymers and plastics, Process innovation, Product innovation, Public sector innovation, Regional development, Regulatory framework for innovation, Related to industrial policy, Related to regional development, Resources efficiency, Social Networks, Social innovation, Sustainable design (for recycling, for environment, eco-design), Sustainable innovation, Technological innovation, Textiles, Textiles including synthetic dyes, colours, fibres, Urban studies, regional studies, Waste, Waste management, Waste recycling, circular economy, place-based innovation, product refurbishment, textiles reuse