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INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed) is sponsored by National Institutes of Health (NIH). The INCLUDE Project invites researchers studying Down syndrome and co-occurring conditions to submit applications for transformative research. This R01 specifically excludes clinical trials.
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Opportunity Listing - INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed) INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed) Agency: National Institutes of Health Assistance Listings: 93. 310 -- Trans-NIH Research Support 93. 867 -- Vision Research 93.
847 -- Diabetes, Digestive, and Kidney Diseases Extramural Research 93. 840 -- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders 93. 846 -- Arthritis, Musculoskeletal and Skin Diseases Research 93.
173 -- Research Related to Deafness and Communication Disorders 93. 837 -- Cardiovascular Diseases Research 93. 855 -- Allergy and Infectious Diseases Research 93.
351 -- Research Infrastructure Programs 93. 839 -- Blood Diseases and Resources Research 93. 350 -- National Center for Advancing Translational Sciences 93.
395 -- Cancer Treatment Research 93. 121 -- Oral Diseases and Disorders Research 93. 865 -- Child Health and Human Development Extramural Research 93.
242 -- Mental Health Research Grants 93. 838 -- Lung Diseases Research 93. 879 -- Medical Library Assistance 93.
233 -- National Center on Sleep Disorders Research Last Updated: May 13, 2026 View version history on Grants. gov The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome.
The purpose of this Notice of Funding Opportunity (NOFO) is to solicit Transformative Research Award applications to support individual scientists or groups of scientists proposing groundbreaking, exceptionally innovative, original, and/or unconventional research that has the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies...
related to Down syndrome. Applications are welcome in all topics relevant to Down syndrome-related research or its co-occurring conditions. No preliminary data are required.
Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in research related to Down syndrome.
Federally recognized Native American tribal governments City or township governments Public and Indian housing authorities Special district governments Public and state institutions of higher education Private institutions of higher education Independent school districts Nonprofits non-higher education with 501(c)(3) Nonprofits non-higher education without 501(c)(3) Other Native American tribal organizations For-profit organizations other than small businesses Refer to Section III.
Eligibility Information in the NOFO for additional information on eligibility. Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.
Foreign components, as defined in the NIH Grants Policy Statement, are allowed. Grantor contact information DownSyndromeINCLUDE@mail. nih.
gov DownSyndromeINCLUDE@mail. nih. gov DownSyndromeINCLUDE@mail.
nih. gov File name Description Last updated RFA-OD-27-004-Full-Announcement. html RFA-OD-27-004-Full-Announcement.
html May 12, 2026 04:17 PM UTC Link to additional information Funding opportunity number : Cost sharing or matching requirement : Funding instrument type : Opportunity Category Explanation : Category of Funding Activity : Your account requires additional identity verification.
According to the current listing, eligibility includes: Researchers studying Down syndrome and co-occurring conditions. (General R01 eligibility applies to institutions). Confirm the full requirements in the official notice before applying.
INCLUDE Project: Transformative Research Awards for Down syndrome (R01 Clinical Trial Not Allowed) is funded by National Institutes of Health (NIH). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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