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Leading Edge Acceleration Projects in Health Information Technology (LEAP in Health IT) (NAP-AX-22-001) - Special Emphasis Notice: Develop innovative ways to improve healthcare-data quality to support responsible development of artificial intelligence (AI) tools in healthcare. is sponsored by U.S. Department of Health and Human Services (HHS), Office of the National Coordinator for Health Information Technology (ONC).
This funding opportunity seeks to develop innovative ways to evaluate and improve the quality of healthcare data used by artificial intelligence (AI) tools in healthcare. It also aims to accelerate the adoption of health IT in behavioral health settings.
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LEAP in Health IT Notice of Funding Opportunity - ONC - Office of the National Coordinator for Health Information Technology website belongs to an official government organization in the to the . gov website. Share sensitive information only on official, secure websites.
Grants Management & Process LEAP in Health IT Notice of Funding Opportunity The Leading Edge Acceleration Projects (LEAP) in Health IT funding opportunity will address well-documented and fast emerging challenges that inhibit the development, use, and/or advancement of well-designed, interoperable health IT.
It is expected to further a new generation of health IT development and inform the innovative implementation and refinement of standards, methods, and techniques for overcoming major barriers and challenges as they are identified.
2026 Notice of Funding Opportunity (NOFO) ONC published a notice of funding opportunity (NOFO) under the Leading Edge Acceleration Projects (LEAP) in Health Information Technology (Health IT) funding opportunity NAP-AX-26-001 .
The goal of the funding opportunity is to accelerate the use of standards-based agentic artificial intelligence technologies to advance clinical care and enable innovation, enhance the Lantern tool’s ability to monitor FHIR endpoints by adding a secure, community‑driven feedback layer, and to assess laboratory data quality and implement existing solutions to improve small independent laboratories’ adoption and use of standard codes.
Area 1: Accelerate the use of agentic artificial intelligence solutions in clinical care. Area 2: Expand Lantern’s API monitoring capabilities by integrating secure, community-driven feedback that complements existing automated checks.
Area 3 : Assess laboratory interoperability gaps to improve the adoption and use of standard terminology among small, independent laboratories The application period closes at 12:00 PM ET on July 16, 2026. Notice of Funding Opportunity (2026) View the full Notice of Funding Opportunity [PDF – 797 KB] Read Frequently Asked Questions Informational Session (2026) An informational session was held on June 23, 2026, at 1:00 PM ET.
Presentation Slides [PDF – 1. 1 MB] 2025 Special Emphasis Notice (SEN) ONC published a Special Emphasis Notice (SEN) under the Leading Edge Acceleration Projects (LEAP) in Health Information Technology (Health IT) funding opportunity NAP-AX-22-001 .
In fiscal year 2025, ONC seeks applications pursuant to the LEAP in Health IT notice of funding opportunity for projects that address one of the following areas of interests: Area 1: Demonstrate readiness of FHIR®-based Subscriptions capability as a foundational health IT capability for improved interactivity with third-party applications.
Area 2: Identify and test innovative technical approaches that would inform future changes to the TEFCA TM infrastructure to increase adoption of Individual Access Service (IAS). The application period closed at 12:00 ET on April 25, 2025.
Special Emphasis Notice (2025) View the full Special Emphasis Notice [PDF -339 KB] Informational Session (2025) An informational session was held March 6, 2025 1:00 PM ET Presentation Slides [PDF – 608 KB] 2024 Special Emphasis Notice (SEN) ONC published a Special Emphasis Notice (SEN) under the Leading Edge Acceleration Projects (LEAP) in Health Information Technology (Health IT) funding opportunity NAP-AX-22-001 .
In 2024, ONC is particularly interested in applications whose specific aims address one of the following areas of interest: Area 1: Develop innovative ways to improve healthcare-data quality to support responsible development of artificial intelligence (AI) tools in healthcare Area 2: Accelerate adoption of health IT in behavioral health settings The application period closed on July 12, 2024 .
All Questions about this SEN should be submitted to ONC-LEAP@hhs. gov View Questions and Answers to the SEN Special Emphasis Notice (2024) View the full Special Emphasis Notice [370 KB] Informational Session (2024) An informational session was held on at 1:00 PM Eastern on May 21, 2024.
Slides from Informational Session [PDF – 15 MB] 2023 Special Emphasis Notice (SEN) ONC published a Special Emphasis Notice (SEN) under the Leading Edge Acceleration Projects (LEAP) in Health Information Technology (Health IT) funding opportunity NAP-AX-22-001 .
In 2023, ONC was particularly interested in applications whose specific aims address one of the following areas of interest: Area 1: Exploring the Use of Advanced Fast Health Care Interoperability Resources (FHIR®) Capabilities Area 2: Identifying Data Quality Improvements for USCDI Data Elements The application period closed on June 12, 2023.
Special Emphasis Notice (2023) View the full Special Emphasis Notice [PDF – 476 KB] View Responses to Questions about Special Emphasis Notice Informational Session (2023) An informational session was held on April 25, 2023 . Presentation Slides [PDF – 14.
6 MB] 2022 Notice of Funding Opportunity (NOFO) ONC published a notice of funding opportunity (NOFO) under the Leading Edge Acceleration Projects (LEAP) in Health Information Technology (Health IT) funding opportunity NAP-AX-22-001 .
In 2022, ONC is particularly interested in applications whose specific aims address one of the following areas of interest: Area 1: Address Health Equity and Social Determinants of Health (SDOH)Through Innovative, Open-Source Technology Tools, and Electronic Health Records (EHRs) Area 2: Demonstrate the Use of Equity-Enhancing Patient-Generated Health Data (PGHD) for Clinical Care and Research Notice of Funding Opportunity (2022) View the full Notice of Funding Opportunity Read Frequently Asked Questions Informational Session (2022) An informational session was held on June 28, 2022.
A video recording of the informational session is below. Information Session Presentation Slides [PDF – 14.
3 MB] 2021 Special Emphasis Notice (SEN) The 2021 Special Emphasis Notice (SEN) asked for applications whose specific aims address one of the following areas of interest: Area 1: Referral Management to Address Social Determinants of Health (SDOH) Aligned with Clinical Care Area 2: Health IT Tools to Make Electronic Health Records (EHRs) Data Research – and Artificial Intelligence (AI)-Ready Special Emphasis Notice (2021) View the full Special Emphasis Notice [PDF- 295 KB] Read Frequently Asked Questions Informational Session (2021) An informational session was held on March 9, 2021.
A video recording of the informational session and the presentation slides are below.
Information Session Presentation Slides [PDF – 945 KB] 2020 Special Emphasis Notice (SEN) The 2020 Special Emphasis Notice asked for applications whose specific aims addressed one of the following areas of interest: Area 1: Advancing Registry Infrastructure for a Modern API-based Health IT Ecosystem Area 2: Cutting Edge Health IT Tools for Scaling Health Research Area 3: Integrating Health Care and Human Services Data to Support Improved Outcomes View the full Special Emphasis Notice [PDF- 264 KB] View recording of informational session View session slides from informational session [PDF – 12 MB] 2019 Special Emphasis Notice (SEN) The 2019 Special Emphasis Notice asked for applications whose specific aims addressed one of the following areas of interest: Area 1: Standardization and Implementation of Scalable Health Level 7 International’s (HL7®) Fast Healthcare Interoperability Resources (FHIR®) Consent Resource Area 2: Design, Develop, and Demonstrate Enhanced Patient Engagement Technologies for Care and Research View the full Special Emphasis Notice [PDF – 250 KB] View recording of informational session 2018 Notice of Funding Opportunity (NOFO) The 2018 Notice of Funding Opportunity was specifically interested in innovative solutions and breakthrough advances in the following areas of interest: Area 1: Expanding the scope, scale, and utility of population-level data-focused application programming interfaces (APIs).
Area 2: Advancing Clinical Knowledge at the Point of Care. View recording of informational session View the full Notice of Funding Opportunity [PDF – 568 KB] Thank you for visiting the HealthIT. gov website!
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According to the current listing, eligibility includes: Not explicitly stated in the provided snippets, but generally for organizations working on health IT. Confirm the full requirements in the official notice before applying.
The current listing shows up to $1,000,000 (estimated for two projects combined). Verify award ceilings, matching requirements, and allowable costs in the official notice.
Applications for Leading Edge Acceleration Projects in Health Information Technology (LEAP in Health IT) (NAP-AX-22-001) - Special Emphasis Notice: Develop innovative ways to improve healthcare-data quality to support responsible development of artificial intelligence (AI) tools in healthcare. are due July 12, 2026. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
Leading Edge Acceleration Projects in Health Information Technology (LEAP in Health IT) (NAP-AX-22-001) - Special Emphasis Notice: Develop innovative ways to improve healthcare-data quality to support responsible development of artificial intelligence (AI) tools in healthcare. is funded by U.S. Department of Health and Human Services (HHS), Office of the National Coordinator for Health Information Technology (ONC). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
NCI Continuing Umbrella of Research Experiences (CURE) Academic Career Excellence (ACE) Award (K32) is a grant from the National Cancer Institute (NCI) that funds early postdoctoral fellows from diverse backgrounds, including underrepresented groups, to pursue research training in cancer-related fields. The K32 award supports fellows within 12 months prior to transitioning into, or within the first two years of, a postdoctoral position. The program, operated through NCI's Center to Reduce Cancer Health Disparities (CRCHD), aims to enhance the pool of qualified diverse cancer researchers. Beginning with the June 12, 2025 due date, the CURE ACE Award is available in both Independent Clinical Trial Required and Independent Clinical Trial Not Allowed versions. Eligible applicants must be U.S. citizens or permanent residents at time of award.
Innovation Grant is a grant from the Delta Dental of Arizona Foundation that funds nonprofit organizations pursuing unique, high-impact projects that improve health and wellness in Arizona communities. This two-year award supports original initiatives with measurable real-world impact, including programs serving underserved and uninsured populations through oral health education, disease prevention, and nutritional access. Projects must demonstrate the potential to make a meaningful difference in the community and stand apart from conventional approaches. Eligible applicants are Arizona-based nonprofit organizations. Awards total $100,000 per recipient over two years. The 2026 application cycle closed October 16, 2025, with recipients notified in late 2025 and funding made available shortly after.
The HHS Grants Policy Statement that took effect October 1, 2025 raised the micro-purchase threshold to $50,000, the single audit threshold to $1 million, and the de minimis indirect cost rate to 15 percent — quietly rewriting the operational rules for tens of billions of dollars in annual awards. Combined with full 2 CFR Parts 200 and 300 adoption and new MAHA-aligned program priorities, it is the biggest compliance shift for health grantees since Uniform Guidance arrived in 2013.
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