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Massachusetts Applied AI Models Innovation Challenge (NOFO No. 2026-JAII-05) is sponsored by Massachusetts AI Hub, a division of the Massachusetts Technology Collaborative (MassTech). This challenge provides funding for AI model development projects that address critical societal and industry challenges across key sectors of the Massachusetts innovation economy, including health care and life sciences.
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Notice of Funding Opportunity Solicitation for Applied AI Models Innovation Challenge | Massachusetts AI Hub Notice of Funding Opportunity Solicitation for Applied AI Models Innovation Challenge Solicitation No. 2026-JAII-05 The Massachusetts AI Hub, a division of the Massachusetts Technology Collaborative (Mass Tech Collaborative or MassTech) is issuing this Notice of Funding Opportunity for the Massachusetts Applied AI Models Innovation Challenge, (NOFO No. 2026-JAII-05) (the NOFO) to solicit responses from qualified firms (Respondents) interested in receiving grant funding for translational funding and contribute to the Data Commons Collaborative (DCC).
These awards will fund AI model development projects that address critical societal and industry challenges across key sectors of the Massachusetts innovation economy: health care, life sciences, financial services, robotics, advanced manufacturing, climate tech and education. This program is designed as translational funding, addressing the gap between early research and real world deployment.
Applicants are invited to propose innovative methods for adapting, evaluating and operationalizing existing AI and ML models, including fine tuning open source models or creating new model components where technically feasible within the one million dollar funding cap. Projects may include training or fine tuning work when it directly supports an applied use case.
Proposals for entirely new model architectures must include strong justification and demonstrate feasibility within program constraints.
Use cases of interest include, but are not limited to: Health Care : clinical decision support, patient care, public health management Life Sciences : drug discovery, genomics, diagnostics Financial Services : fraud detection, underwriting, wealth management Robotics : autonomous navigation, human-robot interaction, precision manipulation Advanced Manufacturing : Digital twins for prototypes, predictive maintenance, supply chain Optimization Climate Tech : carbon reduction, energy efficiency, sustainable materials Education & Society : personalized learning, workforce development, public-interest technology Defense and National Security : intelligence fusion, competitive AI swarms, autonomous logistics, and AI-enabled simulation capabilities or cyberspace operations Full details included in the solicitation linked below.
Team Lead: Sabrina Mansur, proposals@masstech. org Date Issued: Wednesday, January 28, 2026 Questions Due : Friday, February 6, 2026 at 5:00 P. M.
Answers to Questions Posted: Thursday, February 19, 2026 at 10:00 A. M. | Q&A (PDF) Applications Due: Friday, March 6, 2026 by 5:00 P.
M. ( amended 2/18/26) Download Application Documents: Download Solicitation No. 2026-JAII-05 (PDF) ( amended 2/18/26) Download Attachment C - Budget Template (Excel) Get news from the Massachusetts AI Hub delivered to your inbox. This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
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According to the current listing, eligibility includes: The lead or primary applicant must be a college, university, non-profit research institution or other non-profit entity legally organized in Massachusetts. Confirm the full requirements in the official notice before applying.
Massachusetts Applied AI Models Innovation Challenge (NOFO No. 2026-JAII-05) is funded by Massachusetts AI Hub, a division of the Massachusetts Technology Collaborative (MassTech). Verify program details on the funder's official page before applying.
This opportunity targets applicants in Massachusetts. If your organization operates elsewhere, check the official notice for location requirements.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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