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Maximizing Investigators' Research Award (MIRA) for Early Stage Investigators (ESI) is a grant from the National Institutes of Health, administered by the National Institute of General Medical Sciences (NIGMS), that provides stable, flexible funding for the full range of research in an investigator's laboratory that falls within the NIGMS mission.
MIRA aims to increase funding efficiency, enhance scientific productivity, and distribute resources more widely among the nation's most talented investigators. Grants are generally awarded for 5 years. Early stage investigators should apply through PAR-23-145.
Eligible applicants include private and public institutions of higher education. Award amounts are not specified.
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Maximizing Investigators' Research Award (MIRA) (R35) | National Institute of General Medical Sciences MIRA provides support for research in an investigator's laboratory that falls within the mission of NIGMS . The goal of MIRA is to increase the efficiency of NIGMS funding by providing investigators with greater stability and flexibility, thereby enhancing scientific productivity and the chances for important breakthroughs.
The program will also help distribute funding more widely among the nation's highly talented and promising investigators. MIRA grants will generally be for 5 years, for both established investigators/ new investigators and early stage investigators .
With the publication of PAR-26-121 , the program has now expanded to include established investigators who currently hold an NIGMS R01-equivalent grant or who wish to renew a MIRA, as well as new investigators who are not serving as a subproject leader on any multicomponent awards and propose research in the NIGMS mission. Early stage investigators should apply through PAR-23-145 .
MIRA for Established and New Investigators (EIs and NIs) New NOFO Published: PAR-26-121 See below for MIRA for Early-Stage Investigators (ESIs). PAR-26-121 – Applications accepted in 2026-2028 FAQs About MIRA PAR-22-180 MIRA Eligibility for Administrative Supplements MIRA Eligibility Decision Tree EI and NI MIRA Applicant Slides For more information on MIRA for established investigators contact Ashley Barnes, Ph. D.
, and Baishali Maskeri, Ph. D. , at NIGMS_EINIMIRA@nigms.
nih. gov MIRA for Early Stage Investigators (ESIs) PAR-26-032 – MIRA for ESIs Forecast Announcement FAQs About MIRA PAR-23-145 MIRA ESI Applicant Slides PAR-23-145 - Applications accepted through February 3, 2026 Eligibility: NIH Definitions of Early Stage Investigators and Related Policies and Procedures For more information on MIRA for ESIs contact Michelle R. Bond, Ph.
D. , and Marc Rigas, Ph. D.
, at NIGMS-ESIMIRA@nigms. nih. gov .
Virtual Office Hours - Navigating NIGMS Grants MIRA Awards Reflect Innovation of UConn Scientists ASBMB Today Article on MIRA Program This page last updated on
According to the current listing, eligibility includes: Private institutions of higher education, independent school districts, and public and state institutions of higher education. Confirm the full requirements in the official notice before applying.
Maximizing Investigators' Research Award (MIRA) for Early Stage Investigators (ESI) (R35 - Clinical Trial Optional) is funded by National Institutes of Health. Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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