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Find similar grantsMaximizing Investigators' Research Award (MIRA) (R35) is sponsored by National Institute of General Medical Sciences (NIGMS) / National Institutes of Health (NIH). MIRA grants support broader research activities rather than individual projects, providing investigators with greater stability and flexibility to pursue a range of ideas related to biomedical research.
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Maximizing Investigators' Research Award (MIRA) (R35) | National Institute of General Medical Sciences MIRA provides support for research in an investigator's laboratory that falls within the mission of NIGMS . The goal of MIRA is to increase the efficiency of NIGMS funding by providing investigators with greater stability and flexibility, thereby enhancing scientific productivity and the chances for important breakthroughs.
The program will also help distribute funding more widely among the nation's highly talented and promising investigators. MIRA grants will generally be for 5 years, for both established investigators/ new investigators and early stage investigators . Early stage investigators should apply through PAR-27-032 .
MIRA for Established and New Investigators (EIs and NIs) New NOFO Published: PAR-26-121 See below for MIRA for Early-Stage Investigators (ESIs). PAR-26-121 – Applications accepted in 2026-2028 MIRA Eligibility Decision Tree For more information on MIRA for established investigators contact Ashley Barnes, Ph. D.
, and Baishali Maskeri, Ph. D. , at NIGMS_EINIMIRA@nigms.
nih. gov MIRA for Early Stage Investigators (ESIs) PAR-27-032 - Applications accepted through February 6, 2029 Eligibility: NIH Definitions of Early Stage Investigators and Related Policies and Procedures For more information on MIRA for ESIs contact Michelle R. Bond, Ph.
D. , and Marc Rigas, Ph. D.
, at NIGMS-ESIMIRA@nigms. nih. gov .
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According to the current listing, eligibility includes: Established investigators with ongoing research programs in NIGMS mission areas. Confirm the full requirements in the official notice before applying.
Maximizing Investigators' Research Award (MIRA) (R35) is funded by National Institute of General Medical Sciences (NIGMS) / National Institutes of Health (NIH). Verify program details on the funder's official page before applying.
Yes — this listing is flagged as national in scope, so applicants across the U.S. may apply, subject to the sponsor's other eligibility criteria.
Applications go through the funder's official portal — the Apply Now link on this page goes there directly.
Limited Competition: Institutional Development Award (IDeA) for Clinical & Translational Research (CTR) (P30 - CT Optional) is sponsored by National Institute of General Medical Sciences (NIGMS) / National Institutes of Health (NIH). This grant aims to advance gene-based therapies for ultra-rare neurological and neuromuscular disorders. This initiative focuses on IND-enabling studies and supports the development of innovative therapeutics with proven biological rationale.
Focused Technology Research and Development (R01 Clinical Trial Not Allowed) is sponsored by National Institute of General Medical Sciences (NIGMS) / National Institutes of Health (NIH). This Notice of Funding Opportunity (NOFO) supports projects relevant to the NIGMS mission that focus solely on the development of technologies with the potential to enable the acquisition of biomedical knowledge. The project outcome is a working prototype of the technology.
R21 Exploratory Technology Development is sponsored by National Institute of General Medical Sciences (NIGMS) / National Institutes of Health (NIH). This program supports exploratory technology development projects relevant to the NIGMS mission. It is suitable for novel, high-risk projects, and preliminary data is not required. The project outcome is a proof of concept study.
PAR-27-056 replaces the long-running IDeA-CTR U54 cooperative agreement with a P30 center core grant and splits the program into Development and Network tracks. Posted August 19, 2026, with a first estimated due date of October 9. Here is what the mechanism swap actually changes for the 23 IDeA states and Puerto Rico.
Read articleThe memorandum of agreement was signed August 4 and 5, disclosed by House appropriators on September 3, and runs through 2036. It names no dollar figure. Here is what is actually established, what is still speculation, and what researchers holding or planning NIAID biodefense awards should do before September 30.
Read articlePAR-27-054 and PAR-27-055 replace COBRE's Phase 1-2-3 model with two tracks: a 15-year Development-Expansion-Sustainability path and a 10-year Expansion-Sustainability path. At $1.5 million per year in direct costs across 23 states and Puerto Rico, with new research cores prohibited in the final phase and eligibility capped at three active awards per institution, the track you claim is the most consequential choice in the application.
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