Mechanism-Focused Research to Promote Adherence to Healthful Behaviors to Prevent Mild Cognitive Impairment (MCI) and Alzheimers Disease (AD) and AD-Related Dementias (ADRD) (R61/R33 Clinical Trial Required)

Mechanism-Focused Research to Promote Adherence to Healthful Behaviors to Prevent Mild Cognitive Impairment (MCI) and Alzheimers Disease (AD) and AD-Related Dementias (ADRD) (R61/R33 Clinical Trial Required) is sponsored by National Institute on Aging (NIA). This funding opportunity invites applications to research psychological and interpersonal mechanisms that influence adherence to behaviors or lifestyle changes aimed at preventing cognitive decline, Mild Cognitive Impairment (MCI), and Alzheimer's disease (AD) and AD-related dem…

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gov Maintenance Calendar Mechanism-Focused Research to Promote Adherence to Healthful Behaviors to Prevent Mild Cognitive Impairment (MCI) and Alzheimers Disease (AD) and AD-Related Dementias (ADRD) (R61/R33 Clinical Trial Required) Department of Health and Human Services National Institutes of Health Document Type:Grants Notice Funding Opportunity Number:RFA-AG-23-034 Funding Opportunity Title:Mechanism-Focused Research to Promote Adherence to Healthful Behaviors to Prevent Mild Cognitive Impairment (MCI) and Alzheimers Disease (AD) and AD-Related Dementias (ADRD) (R61/R33 Clinical Trial Required) Opportunity Category:Discretionary Opportunity Category Explanation: Funding Instrument Type:Grant Category of Funding Activity:Health Expected Number of Awards: Assistance Listings:93.

866 -- Aging Research Cost Sharing or Matching Requirement:No Last Updated Date:Oct 03, 2022 Original Closing Date for Applications:Jan 20, 2023 Current Closing Date for Applications:Jan 20, 2023 Archive Date:Feb 25, 2023 Estimated Total Program Funding: Eligible Applicants:State governments Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Public housing authorities/Indian housing authorities For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled "Additional Information on Eligibility" for clarification) Independent school districts Private institutions of higher education City or township governments Additional Information on Eligibility:Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

## Additional Information Agency Name:National Institutes of Health Description:This Funding Opportunity Announcement (FOA) invites applications to address psychological and interpersonal mechanisms driving adherence to behaviors or lifestyle changes relevant to prevention of cognitive decline, Mild Cognitive Impairment (MCI), and Alzheimer's disease (AD) and AD-related dementias (ADRD).

Mechanisms of adherence may be studied in new, early- to late-stage (including Stage I-IV) behavior change trials. Applications will seek to identify malleable, mechanistic, psychological, or interpersonal targets that, if modified, will strengthen adherence to, maintenance of, and continued/renewed engagement in behaviors that may promote cognitive health and prevent AD/ADRD.

This FOA utilizes the R61/R33 Exploratory/Developmental Phased Award activity code. The R61 phase will support pilot research to identify, measure, and assess the malleability of psychological or interpersonal adherence-relevant targets that, if successful, can transition to the R33 phase. The R33 phase will utilize results from the R61 phase to implement rigorous, proof-of-concept intervention studies.

The transition from the R61 to the R33 phase will be administratively reviewed for, and be dependent upon, successful completion of the go/no-go criteria specified for the R61 phase. Link to Additional Information:https://grants. nih.

gov/grants/guide/rfa-files/RFA-AG-23-034. html Grantor Contact Information:If you have difficulty accessing the full announcement electronically, please contact: See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

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