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"MIT and Mass General Brigham AI Cures Grants for Clinical AI Research with High Translational Potential" is currently closed and not accepting applications.
This is a paired-PI seed grant run jointly by MIT and Mass General Brigham under the AI Cures banner, and its defining feature is structural rather than thematic: a proposal is only eligible if it has one principal investigator at MIT and one at MGB. That single condition determines who can realistically apply, and it is the reason many otherwise strong clinical AI groups are shut out.
Each MIT-MGB PI pair may submit only one proposal per cycle, so the collaboration itself has to be settled before drafting begins. Scope is clinical AI with high translational potential - explicitly diagnostics, treatment, and long-term outcome prediction for diverse patient populations - rather than foundational machine learning.
Review weights translational potential and novelty of approach, which in practice means a proposal that describes an interesting method without a credible path into clinical use will score poorly. Two terms deserve attention before committing. First, all code produced must be publicly released under the MIT licence or another open source licence.
Second, neither institution will pursue patent applications on research outcomes. Groups with commercialisation plans or existing industry sponsorship should check those commitments against this RFP before applying, because the no-patent term is unusual for clinical AI funding at this scale and is not negotiable after award. Awardees must also commit to annual reporting and to presenting at the MIT-MGB AI Cures Conference.
The proposal itself is short - two pages maximum excluding references, 10-point minimum font, one-inch margins - covering goals, translational potential, methodology, datasets, deliverables and budget. Short-form proposals reward specificity about the dataset and the clinical endpoint far more than they reward background review.
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Or search similar grants →According to the current listing, eligibility includes: Each proposal requires one principal investigator from MIT and one principal investigator from Mass General Brigham; single-institution proposals are not eligible. Each MIT-MGB PI collaboration may submit a maximum of one proposal per cycle. Projects must focus on clinical AI research with high translational potential, aimed at facilitating the translation and adoption of AI technologies to improve health, including diagnostics, treatment, and long-term outcome prediction for diverse patient populations. Submissions are limited to a two-page proposal excluding references, at 10-point minimum font with one-inch margins, identifying both collaborators and covering goals, translational potential, methodology, datasets, deliverables and budget, plus separate budget templates for each institution. Awards are up to 250,000 dollars per project, split evenly as 125,000 dollars per institution, with up to six awards available. Awardees must commit to annual reporting and to presenting at the MIT-MGB AI Cures Conference. Two binding conditions apply to results: all code produced in the collaborative effort must be publicly released under the MIT licence or another open source licence, and neither institution will pursue patent applications on the research outcomes. The documented deadline is 11 September 2026. Enquiries are directed to Ignacio Fuentes (ifuentes@mit.edu) for MIT PIs and Shawn Murphy (snmurphy@mgb.org) for MGB PIs. Confirm the current cycle's deadline, award ceiling and terms on the MIT Jameel Clinic RFP page before preparing a submission. Confirm the full requirements in the official notice before applying.
The current listing shows up to 250,000 US dollars per award, structured as a split of 125,000 dollars to the MIT principal investigator and 125,000 dollars to the Mass General Brigham principal investigator. Up to six awards are available, for a total programme value of up to 1,500,000 dollars. amount_min is set to 250,000 and amount_max to 250,000 because the RFP states a single fixed per-award ceiling rather than a range; the two 125,000 dollar halves are components of one 250,000 dollar award, not separate awards. Separate budget templates must be submitted for each institution. No published minimum exists and the RFP does not describe an indirect cost allowance, so budgets should be built assuming the 125,000 dollars per institution is the working figure. Verify award ceilings, matching requirements, and allowable costs in the official notice.
The published deadline was September 11, 2026, which has passed. Check the official notice for any future application windows before investing time in a proposal.
MIT and Mass General Brigham AI Cures Grants for Clinical AI Research with High Translational Potential is funded by Massachusetts Institute of Technology (MIT) and Mass General Brigham (MGB), through the MIT Jameel Clinic AI Cures program. Verify program details on the funder's official page before applying.
This opportunity targets applicants in MA. If your organization operates elsewhere, check the official notice for location requirements.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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