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Model-to-Clinic (M2C) for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (UG3/UH3, Clinical Trial Optional) is sponsored by National Cancer Institute (NCI) / NIH Common Fund. The overarching goal of this funding opportunity and its companion opportunities is to advance precision medicine with AI by integrating imaging with multimodal data.
It supports innovative clinical informatics research to transform health data into actionable knowledge.
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Or search similar grants →According to the current listing, eligibility includes: Nonprofits, non-higher education with or without 501(c)(3). While the direct listing mentions non-higher education, the broader NCI AI in Cancer Research page mentions universities and research institutions as eligible for programs with a strong emphasis on AI, and PRIMED-AI is listed there. Confirm the full requirements in the official notice before applying.
Applications for Model-to-Clinic (M2C) for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (UG3/UH3, Clinical Trial Optional) are due October 19, 2026. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
Model-to-Clinic (M2C) for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (UG3/UH3, Clinical Trial Optional) is funded by National Cancer Institute (NCI) / NIH Common Fund. Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Past winners and funding trends for this program
NOT-RM-26-004 asks the public for NIH-wide research challenges worth a 10-year, cross-institute program. There is no budget, no biosketch, no page limit, and no award. What there is: the five criteria every Common Fund investment has met since 2006, a new bullet about small-lab burden, and a fund whose FY 2026 request came in at $347.4 million — down 49.3 percent.
Read articleThe NIH Common Fund launched PRIMED-AI — Precision Medicine with AI: Integrating Imaging with Multimodal Data — as five coordinated funding opportunities (RFA-RM-27-011 through -015) that build a full pipeline from standards to clinic. Here is how the Playbook, Data-to-Model partnerships, Model-to-Clinic translation, Validation Center, and Logistics Center fit together, what each pays, who is eligible, and how to position before the October 2026 deadlines.
Read articleAvoid common NIH grant proposal mistakes including vague specific aims, weak methodology, and poor budget justification that lead to rejection.
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