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Model-to-Clinic (M2C) for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (UG3/UH3, Clinical Trial Optional) is sponsored by National Institutes of Health (NIH) - Common Fund.
This program aims to establish the Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) Program to support the development of innovative, reliable, cost-effective, and sustainable multimodal AI-based clinical decision support (CDS) tools.
PRIMED-AI CDS tools are based on the integration of clinical imaging with other types of multimodal health data to enhance care for patients with a wide range of health conditions. This NOFO specifically catalyzes the translation of AI-enabled, image-centered, multimodal CDS tools from prototypes towards clinical applications.
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Or search similar grants →According to the current listing, eligibility includes: Nonprofits, Public and state institutions of higher education; Private institutions of higher education, Government entities, For-profit organizations other than small businesses; Small businesses. Confirm the full requirements in the official notice before applying.
Applications for Model-to-Clinic (M2C) for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (UG3/UH3, Clinical Trial Optional) are due October 19, 2026. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
Model-to-Clinic (M2C) for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (UG3/UH3, Clinical Trial Optional) is funded by National Institutes of Health (NIH) - Common Fund. Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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Validation Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U54 Clinical Trials Not Allowed) is sponsored by National Institutes of Health (NIH) - Common Fund. The Validation Center will serve as a hub for validating AI-enabled, multimodal CDS tools, supporting reproducibility, interoperability, and clinical translation in precision medicine.
Logistics Center for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (U24 Clinical Trials Not Allowed) is sponsored by National Institutes of Health (NIH) - Common Fund. This opportunity funds the creation of a Logistics Center to coordinate PRIMED-AI activities, fostering collaboration and standardization in AI-based clinical data integration.
Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) Development and Testing of Multi-use Frameworks Playbook is sponsored by National Institutes of Health (NIH) - Common Fund. This program funds the development and testing of multi-use frameworks and playbooks for integrating imaging with multimodal data using AI in precision medicine.
NOT-RM-26-004 asks the public for NIH-wide research challenges worth a 10-year, cross-institute program. There is no budget, no biosketch, no page limit, and no award. What there is: the five criteria every Common Fund investment has met since 2006, a new bullet about small-lab burden, and a fund whose FY 2026 request came in at $347.4 million — down 49.3 percent.
Read articleThe NIH Common Fund launched PRIMED-AI — Precision Medicine with AI: Integrating Imaging with Multimodal Data — as five coordinated funding opportunities (RFA-RM-27-011 through -015) that build a full pipeline from standards to clinic. Here is how the Playbook, Data-to-Model partnerships, Model-to-Clinic translation, Validation Center, and Logistics Center fit together, what each pays, who is eligible, and how to position before the October 2026 deadlines.
Read articleAvoid common NIH grant proposal mistakes including vague specific aims, weak methodology, and poor budget justification that lead to rejection.
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