Molecular Biophysics Training Grant

Molecular Biophysics Training Grant is sponsored by National Institutes of Health (NIH). This program provides support for Ph. D.

students in Molecular Biophysics, focusing on interdisciplinary and collaborative research.

Molecular Biophysics Training Grant Project Number 5T32GM008572-15 Contact PI/Project Leader BRENOWITZ, MICHAEL D. DESCRIPTION (provided by applicant): This application requests continued support for a Ph. D.

Training Program in Molecular Biophysics, which is currently in its tenth year of existence. The training faculty in this proposal primarily have appointments in two closely allied departments, Biochemistry and Physiology & Biophysics.

Through required and elective courses, participation in research seminars and discussion groups and, most importantly, through individual research, the student trainees develop the technical skills and critical ability necessary to conduct independent research in Molecular Biophysics.

Training consists of three to four years of individual research, often with joint mentoring, after a first year that consists entirely of coursework and laboratory rotations. Both the course work and research training of each student are closely monitored by the Steering Committee for the program.

The cohesiveness of the program is assured by regular meetings of the training faculty and trainees under the guidance of the Steering Committee as well as by Core courses taken by all trainees. This program provides valuable training opportunities for students in Molecular Biophysics due to the outstanding faculty and facilities that exist at the Institution In two areas in particular, the program provides unparalleled opportunities.

These include synchrotron and laser spectroscopy research. Beamline facilities operated by the College of Medicine at the National Synchrotron Light Source include student access to state-of-the art protein crystallography, x-ray absorption spectroscopy x-ray footprinting, and infrared microspectroscopy techniques.

Also, the laser facilities of the College include several laboratories with state-of-the art femtosecond to microsecond time-resolved instrumentation for the study of protein folding and dynamics for student research.

The research areas that are especially strong in the trainer's laboratories are Structural Biology, including macromolecular NMR and crystallography time-resolved investigations of protein and nucleic acid folding and protein dynamics; structure function relationships of metalloproteins, metalloenzymes, and enzymes; and allostenc interactions of macromolecules The two departments involved in this proposal are currently attracting excellent trainee candidates and have trained numerous students in the past who have excellent outcomes.

The program currently provides training for six pre-doctoral students in each year; this proposal suggests an increase to seven slots per year. Public Health Relevance Statement No NIH Spending Category available. Biophysics Grant Molecular Training [Biomedical Research and Research Training Review Subcommittee B[BRT-B]](https://public.

csr. nih. gov/StudySections/StandingStudySections) Administering Institutes or Centers National Institute of General Medical Sciences Assistance Listing Number Project Funding Information for 2009 No Sub Projects information available for 5T32GM008572-15 Publications are associated with projects, but cannot be identified with any particular year of the project or fiscal year of funding.

This is due to the continuous and cumulative nature of knowledge generation across the life of a project and the sometimes long and variable publishing timeline. Similarly, for multi-component projects, publications are associated with the parent core project and not with individual sub-projects.

No Publications available for 5T32GM008572-15 No Patents information available for 5T32GM008572-15 The Project Outcomes shown here are displayed verbatim as submitted by the Principal Investigator (PI) for this award. Any opinions, findings, and conclusions or recommendations expressed are those of the PI and do not necessarily reflect the views of the National Institutes of Health. NIH has not endorsed the content below.

No Outcomes available for 5T32GM008572-15 No Clinical Studies information available for 5T32GM008572-15 No news release information available for 5T32GM008572-15 No Historical information available for 5T32GM008572-15 No Similar Projects information available for 5T32GM008572-15 ## Select options for export: