Multimodal Digital Biomarkers Grant

The Horizon Europe 2026 Cluster 1 Health work programme funds Virtual Human Twin (VHT) projects that combine AI, multimodal patient data, mechanistic biological models, and high-performance computing to build personalized virtual representations of cancer patients for diagnostics, treatment planning, and therapy response prediction. The VHT initiative supports interdisciplinary consortia developing AI-driven digital twins of cancer patients integrating imaging, genomics, proteomics, electronic health records, and physiological measurements with mechanistic and machine learning models. Funded projects must demonstrate clinical validation pathways and integration with European Health Data Space infrastructure. The cancer-focused VHT calls are part of the European Commission's broader €14 billion Horizon Europe 2026-2027 Work Programme adopted December 11, 2025, with at least 35% of the total budget (approximately €4.9 billion) dedicated to climate and health priorities. Cancer Mission calls close September 15, 2026 at 17:00 CET.

The Sony Research Award Program is Sony's principal academic collaboration instrument, and the Focused Research Award track funds joint work between university faculty and Sony Research on a published list of specific problems rather than open-ended investigator-defined topics. The 2026 cycle carries ten focus areas, most of which sit squarely in modern AI: internal mechanisms of multimodal generative models for content creation, knowledge representation and reasoning for graph-based modelling, psychology-informed user modelling for content streaming, post-training of speech language models, AI-powered visual technology, digital human content creation for sports, provenance proofs for AI-generated derivative content, and long-term memory for sequential decision-making in gaming. Awards are up to 150,000 dollars per year for a one-year research period with possible renewal, paid as a single all-inclusive sum. Because the tracks are tightly specified, the decisive factor in a competitive proposal is demonstrable alignment with the named focus area and with the Sony research group that owns it - a strong proposal against an adjacent problem generally does worse than a merely good proposal against the stated one. Eligibility is restricted to full-time professors or researchers qualified to supervise PhD students; adjunct faculty and professors emeritus are excluded. The 2026 application deadline is 15 September 2026.

This funding opportunity is authorized under the “Legislative Branch Appropriations Act of 2023” (Pub. L. 117-389 (H.R. 8237)), subject to availability of funding. The resulting awards will be subject to the Library of Congress Regulation (LCR) 7-310. In addition, while the Library, as a legislative agency, is not subject to 2 CFR 200 – Uniform Administrative Requirements, Costs Principles and Audit Requirements for Federal Awards, the resulting awards will be subject to selective provisions of 2 CFR 200 as determined by the Library and indicated in this NOFO. About the Library of Congress The Library of Congress is the largest library in the world, with millions of books, films and video, audio recordings, photographs, newspapers, maps and manuscripts in its collections. The Library is the main research arm of the U.S. Congress. It is the nation’s oldest federal cultural institution. The Library’s mission is to engage, inspire, and inform Congress and the American people with a universal and enduring source of knowledge and creativity. About the Teaching with Primary Sources Program (TPS) The Teaching with Primary Sources program (www.loc.gov/teachers) has been the Library of Congress’s premier educational grant program since 2006. The goals of the program have included providing instructional materials, tools, education and professional development that enhance teachers’ ability to integrate digitized primary sources from the Library of Congress into instruction that builds student literacy, critical thinking skills, content knowledge and ability to conduct original research. Since the establishment of the Center for Learning, Literacy and Engagement in 2018, and the release of the Library’s 2024-2028 Strategic Plan, the TPS goals both influence and reflect the Library’s broader outreach goals. About the Lewis-Houghton Civics and Democracy Initiative (LHI) Named in honor of Rep. John R. Lewis (D-GA) and Rep. Amo Houghton (R-NY), the Lewis-Houghton Civics and Democracy Initiative (LHI) is included under the Teaching with Primary Sources (TPS) program. In the joint explanatory statement for the Legislative Branch Appropriations Act, 2023, Congress established the Lewis-Houghton Civics and Democracy Initiative and appropriated funds to the Library of Congress to award grants to eligible organizations within the United States (U.S.) and its territories to develop digitally-enabled, creative arts-driven projects focused on using the digitized primary sources of the Library of Congress to teach history, civics and/or democracy. More information and a description of past LHI-funded projects can be found at: https://www.loc.gov/programs/teachers/about-this-program/teaching-with-primary-sources-partner-program/lewis-houghton/. TPS Educational Consortium Grantee organizations become members of the TPS Educational Consortium. They include a wide variety of educational organizations including school districts, libraries, cultural institutions, universities and technology firms that have received Library funding to deliver teacher professional development, create teaching materials and develop apps and online interactives, based on Library of Congress materials. TPS Consortium members are valued as “Connectors” who help the Library achieve its vision of connecting to all Americans. TPS Consortium members extend the Library’s reach by connecting hundreds of thousands of American educators and learners, including K-12 teachers and their students, to Library of Congress methods and materials. Consortium members collaborate, co-create, share ideas, network and actively participate as an educational community. Purpose The purpose of this notice is for the Library of Congress to solicit project proposals from eligible organizations and select awardee organizations that will design and implement educational projects in which the Library’s music or creative arts-related digitized primary sources and other online materials are central to teaching and learning about history, civics, and/or democracy. Awards made under Lewis-Houghton Civics and Democracy Initiative must include rights-free materials from the Library’s music or creative arts digital collections, to develop curriculum, teaching materials, educational programs, pedagogical approaches, and/or other tools for history, civic and democracy instruction targeted toward middle and high school educators and learners. LHI awards should center on inquiry-driven analysis of primary sources, build learners’ civic skills and foster participation in our nation’s democracy. In addition to highlighting primary sources from the Library’s collections of music, dance, theater, visual arts, folk arts, film, photography, book arts, arts and literary manuscripts, and/or other creative arts, proposals may also include the use of arts-based pedagogies and other creative approaches. All proposals must expand the body of innovative strategies, tools, and materials for meaningful teaching and learning with Library of Congress materials. The focus of LHI awards includes the design of educational projects using Library of Congress materials for use in and outside of formal classroom settings. In addition to using Library primary sources to deliver history, civics, and/or democracy learning experiences integrating the arts, projects must address demonstrated educational needs of specific recipient populations and provide solutions that standard practice, documented experience, or research suggest would be effective. Organizations that receive LHI awards make up a subset of the TPS Educational Consortium whose work spans areas of interest including but not limited to arts integration, civics education, multimodal learning, and teaching with audiovisual primary sources. Funded projects will support the Library’s mission to use its collections to connect with all Americans, including those representing multiple communities, beliefs and endeavors, to engage, inspire and inform Congress and the American people with a universal and enduring source of knowledge and creativity. Projects must use the Library’s digital collections for one or more of the following approaches: a) Deliver educational programming to various categories of educators and learners in secondary education (middle and high school); b) Create and distribute educational materials or tools for teaching specific content in history, civics, and/or democracy; c) Convene meetings of like organizations to devise strategies for furthering common learning and teaching goals with Library of Congress materials related to music and/or the arts; and/or d) Conduct research with significant practitioner involvement that investigates the impact of incorporating Library of Congress music and/or creative arts collections into history, civics, and/or democracy educational initiatives. Questions and Answers General Questions and Answers: All questions relating to this Notice must be submitted via email to tps-grant@loc.gov no later than the date stated in Section B of the Notice (“General Questions Submission Deadline”). “The subject of each e-mail must read as follows: Notice 030ADV26R0050 – Lewis-Houghton Initiative New Awards – 2027.” Answers will be provided in a Q&A document uploaded to grants.gov. Questions received after the deadline(s) stated in Section B above may not be answered. Technical Questions Submission: Applicants experiencing problems with submitting proposals can request technical assistance until the date specified in Section B above (“Technical Questions Submission Deadline”). Funding Opportunity Number: 030ADV26R0050. Assistance Listing: 42.015. Funding Instrument: CA. Category: ED. Award Amount: Up to $100K per award.