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Multiple Sclerosis Research Program (MSRP) Clinical Trial Award is sponsored by Congressionally Directed Medical Research Programs (CDMRP). Supports rapid implementation of clinical trials with the potential to significantly impact multiple sclerosis. Clinical trials may evaluate promising new products, pharmacologic agents (drugs or biologics), devices, clinical guidance, and/or emerging approaches and technologies.
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Due to routine system maintenance the CDMRP website will be unavailable from COB 24 April - 27 April COB.
DEPARTMENT OF WAR - CONGRESSIONALLY DIRECTED MEDICAL RESEARCH PROGRAMS Transforming Health Care through Innovative and Impactful Research Multiple Sclerosis Research Program FY26 Multiple Sclerosis Research Program (MSRP) Synopsis of FY26 MSRP Award Mechanisms - (Adobe PDF) - provides a brief description and key elements of the award mechanism.
Program Announcement/Instructions Pre-Application (Letter Of Intent): August 13, 2026 11:59 p. m. Eastern Time Early Investigator Research Award Pre-Application (Letter Of Intent): August 13, 2026 11:59 p.
m. Eastern Time Exploration - Hypothesis Development Award Pre-Application (Letter Of Intent): August 13, 2026 11:59 p. m.
Eastern Time Investigator Initiated Research Award Pre-Application (Letter Of Intent): August 13, 2026 11:59 p. m. Eastern Time For further information, please send e-mail To: CDMRP Webmaster - for download-related questions Help@ebrap.
org - for program announcement-related questions Last updated Thursday, May 7, 2026
According to the current listing, eligibility includes: Not explicitly stated, but implies researchers and institutions capable of conducting clinical trials. Must address focus areas like promoting repair, neuroprotection, remyelination, and treatment of MS symptoms. Confirm the full requirements in the official notice before applying.
Multiple Sclerosis Research Program (MSRP) Clinical Trial Award is funded by Congressionally Directed Medical Research Programs (CDMRP). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
The Congressionally Directed Medical Research Programs just released $1.27 billion across 34 programs. Universities, nonprofits, and small businesses are all eligible.
Read articleCDMRP's FY26 portfolio funds 34 programs, and October 2026 is dense with full-application deadlines: PRCRP October 5, PCRP October 7, MRP October 14. Every one of them is gated behind a pre-application that closed months earlier. Here is what that two-step structure actually costs applicants, and how to be inside the gate for FY27.
Read articleCDMRP reissued the FY26 BCRP Breakthrough Award Levels 1 and 2 and the Clinical Research Extension Award on September 3, 2026, with a November 4 pre-application deadline and a November 18 full application deadline. Round one closed July 8. The arithmetic across both windows accounts for nearly the entire FY26 appropriation — which tells you what kind of second chance this is.
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