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NATIONAL CANCER INSTITUTE (NCI) SMALL BUSINESS INNOVATION RESEARCH (SBIR) INNOVATIVE CONCEPT PHASE I AWARD PROGRAM is sponsored by National Cancer Institute (NCI). This Phase I SBIR contract solicitation from the NCI invites small businesses to submit research proposals for early-stage, innovative, and transformative technologies addressing rare and/or pediatric cancers.
The program supports demonstrating proof-of-concept and feasibility.
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Innovative Concept Award - NCI Notice Number: 75N98026R00109 Deadline for Receipt of Questions: Saturday, August 1, 2026 Deadline for Receipt of Proposals: Monday, September 21, 2026, at 5:00 p. m.
ET Episode 12 | NCI SBIR Innovative Concept Award Listen to this podcast episode to hear the NCI SBIR Team Leader Monique Pond and Program Director William Bozza discuss how Innovative Concept Award supports biotech innovations focused on pediatric and rare cancers.
The NCI Small Business Innovation Research (SBIR) Innovative Concept Award offers $300,000 to small businesses developing highly innovative and transformative technologies that have the potential to create new scientific paradigms and establish entirely new and improved approaches to significantly improve research, prevention, detection, and care in pediatric and rare cancers.
This award is a contract funding opportunity, so applicants must submit their proposal through the Contract Proposal Submission website . Review criteria is heavily weighted for innovation. Preliminary data is not required, expected, or used as a review criteria.
Projects are expected to have a high risk of failure with concomitant high reward. This award is issued relatively quickly following proposal submission. Offerors are strongly encouraged to submit a two- to three-page white paper describing their technology and aims for programmatic feedback before submitting a final proposal.
Offerors will be expected to participate in the NIH I-Corps program to receive entrepreneurial training and assistance. Additional funds will be provided for participating companies. Only proposals from eligible small businesses will be considered for the award.
The business size standard for SBIR program eligibility is established by law regardless of the NAICS Code assigned. To be considered a small business, the business concern must have no more than 500 employees, including the employees of its affiliates. See 13 C.
F. R. § 121.
702. Other requirements apply, as well—see the U.S. Small Business Administration’s SBIR Policy Directive for further eligibility requirements: SBIR-STTR_Policy_Directive_2023. pdf .
Kathleen Sears ( ncioasbir@mail. nih. gov )
According to the current listing, eligibility includes: Small business concerns with the capability to conduct research and development (R&D) in health-related topic areas, specifically those developing technologies for pediatric and/or rare cancers. Confirm the full requirements in the official notice before applying.
The current listing shows not specified, but SBIR/STTR awards can range from $300,000 to $4.5 million. Verify award ceilings, matching requirements, and allowable costs in the official notice.
Applications for NATIONAL CANCER INSTITUTE (NCI) SMALL BUSINESS INNOVATION RESEARCH (SBIR) INNOVATIVE CONCEPT PHASE I AWARD PROGRAM are due September 21, 2026. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
NATIONAL CANCER INSTITUTE (NCI) SMALL BUSINESS INNOVATION RESEARCH (SBIR) INNOVATIVE CONCEPT PHASE I AWARD PROGRAM is funded by National Cancer Institute (NCI). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science (SCH) is sponsored by National Science Foundation (NSF) & National Institutes of Health (NIH). This interagency program supports high-risk, high-reward advances in AI and data science for biomedical and public health research. Projects must cross disciplinary boundaries.
Innovation Grant is a grant from the Delta Dental of Arizona Foundation that funds nonprofit organizations pursuing unique, high-impact projects that improve health and wellness in Arizona communities. This two-year award supports original initiatives with measurable real-world impact, including programs serving underserved and uninsured populations through oral health education, disease prevention, and nutritional access. Projects must demonstrate the potential to make a meaningful difference in the community and stand apart from conventional approaches. Eligible applicants are Arizona-based nonprofit organizations. Awards total $100,000 per recipient over two years. The 2026 application cycle closed October 16, 2025, with recipients notified in late 2025 and funding made available shortly after.