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Find similar grantsNational Institutes of Health (NIH) Small Business Transition Grant (R41/R42) is sponsored by National Institutes of Health (NIH). This opportunity supports mission-aligned projects and measurable outcomes.
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Opportunity Listing - Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional) Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional) Agency: National Institutes of Health Assistance Listings: 93. 859 -- Biomedical Research and Research Training 93. 840 -- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders 93.
361 -- Nursing Research 93. 173 -- Research Related to Deafness and Communication Disorders 93. 213 -- Research and Training in Complementary and Integrative Health 93.
279 -- Drug Use and Addiction Research Programs 93. 172 -- Human Genome Research 93. 233 -- National Center on Sleep Disorders Research 93.
838 -- Lung Diseases Research 93. 865 -- Child Health and Human Development Extramural Research 93. 839 -- Blood Diseases and Resources Research 93.
113 -- Environmental Health 93. 350 -- National Center for Advancing Translational Sciences 93. 837 -- Cardiovascular Diseases Research 93.
867 -- Vision Research 93. 121 -- Oral Diseases and Disorders Research 93. 273 -- Alcohol Research Programs 93.
846 -- Arthritis, Musculoskeletal and Skin Diseases Research 93. 879 -- Medical Library Assistance Last Updated: May 27, 2026 View version history on Grants.
gov The National Institutes of Health (NIH), including the participating Institutes, Centers and Offices, intends to publish a Notice of Funding Opportunity (NOFO) to invite eligible United States small business concerns (SBCs) to submit Small Business Technology Transfer (STTR) Phase I, and Fast-Track grant applications for the Small Business Transition Grant.
Through this NOFO, NIH will support early-career scientists transitioning to entrepreneurship. In addition to funding research and development efforts at the SBC, a major component of this NOFO is entrepreneurial training, mentoring, and career development of the PD/PI. Applications are not being solicited at this time.
Notice is being provided to allow potential applicants sufficient time to develop responsive projects, including identification of complementary industry mentors and career development resources. This NOFO will utilize the R41/R42 activity code.
United States small businesses that have the research capabilities and technological expertise to contribute to the R&D mission(s) of the NIH awarding components identified in this NOFO are encouraged to begin to consider applying for this new NOFO. This opportunity is available to first-time Principal Investigators, and key personnel must include a mentor with measurable effort committed to the project.
Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir. gov/apply) are eligible to submit applications for this opportunity. Individuals are eligible to serve as the PD/PI if they have never been an independent PD/PI on an NIH or CDC research, or corresponding non-NIH peer-reviewed research grant, and are a U.S. Citizen or Lawful Permanent Resident.
Grantor contact information NIH SEED (Small business Education and Entrepreneurial Development) Office of Extramural Research (OER) No documents are currently available.
Link to additional information Estimated Application Due Date : Estimated Due Date Description : Estimated Project Start Date : Funding opportunity number : Cost sharing or matching requirement : Funding instrument type : Opportunity Category Explanation : Category of Funding Activity : Your account requires additional identity verification.
According to the current listing, eligibility includes: Small business concerns (SBCs) that employ and develop entrepreneurial Program Directors/Principal Investigators (PDs/PIs) with research, technology development, and healthcare delivery skills, but limited entrepreneuri…. Confirm the full requirements in the official notice before applying.
The current listing shows up to $400,000 for Phase I (R43) and $2 million for Phase II (R44). Verify award ceilings, matching requirements, and allowable costs in the official notice.
Applications for National Institutes of Health (NIH) Small Business Transition Grant (R41/R42) are due September 1, 2027. Build your timeline backwards from this date to cover registrations, approvals, and final submission checks.
National Institutes of Health (NIH) Small Business Transition Grant (R41/R42) is funded by National Institutes of Health (NIH). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
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Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science (SCH) is sponsored by National Science Foundation (NSF) & National Institutes of Health (NIH). This interagency program supports high-risk, high-reward interdisciplinary projects that leverage AI, machine learning, and advanced data science to address pressing questions in biomedical and public health research. It seeks to advance fundamental scientific and engineering contributions across disciplines to solve key health problems.
NIH R25 Summer Research Education Experience Program is a grant from the National Institutes of Health (NIH) that funds universities and institutions of higher education to provide summer research experiences in environmental health sciences to high school students, college undergraduates, and science teachers. Administered through the National Institute of Environmental Health Sciences (NIEHS), the program aims to attract young people to scientific careers and help teachers communicate about the scientific process more effectively. Eligible applicants are U.S. institutions eligible for NIH grants. The application deadline was March 17, 2026.
NCI Continuing Umbrella of Research Experiences (CURE) Academic Career Excellence (ACE) Award (K32) is a grant from the National Cancer Institute (NCI) that funds early postdoctoral fellows from diverse backgrounds, including underrepresented groups, to pursue research training in cancer-related fields. The K32 award supports fellows within 12 months prior to transitioning into, or within the first two years of, a postdoctoral position. The program, operated through NCI's Center to Reduce Cancer Health Disparities (CRCHD), aims to enhance the pool of qualified diverse cancer researchers. Beginning with the June 12, 2025 due date, the CURE ACE Award is available in both Independent Clinical Trial Required and Independent Clinical Trial Not Allowed versions. Eligible applicants must be U.S. citizens or permanent residents at time of award.
Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science (SCH) is sponsored by National Science Foundation (NSF) & National Institutes of Health (NIH). This interagency program supports high-risk, high-reward interdisciplinary projects that leverage AI, machine learning, and advanced data science to address pressing questions in biomedical and public health research. It seeks to advance fundamental scientific and engineering contributions across disciplines to solve key health problems.
As of October 1, 2025, NIH no longer posts Notices of Funding Opportunity in the NIH Guide — Grants.gov is now the single official source (NOT-OD-25-143). The weekly Guide table-of-contents email that thousands of investigators relied on to discover funding no longer lists opportunities. Combined with the January 25, 2026 SciENcv certified-PDF requirement, the mechanics of finding and applying for NIH money have changed underneath everyone. Here is how to rebuild your discovery workflow so nothing slips through.
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