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National Library of Medicine (NLM) Small Business Research & Development Support (SBIR/STTR) is sponsored by National Library of Medicine (NLM). This program provides grants to small businesses undertaking informatics research and development in medical and biological fields, with specific interest in areas like AI techniques for characterizing and minimizing errors in health-related data sets, novel platforms for integration of patient data, and tools to enhance security of biomedical data, including personal health data.
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Or search similar grants →According to the current listing, eligibility includes: U.S. for-profit small businesses with fewer than 500 employees. Confirm the full requirements in the official notice before applying.
National Library of Medicine (NLM) Small Business Research & Development Support (SBIR/STTR) is funded by National Library of Medicine (NLM). Verify program details on the funder's official page before applying.
Start from the official opportunity page linked in this listing — it carries the sponsor's submission instructions.
Past winners and funding trends for this program
PAR-26-042 funds NLM-priority clinical informatics R01 grants up to $250,000 in direct costs per year through March 6, 2029, with standard NIH cycles on October 5, February 5, and June 5. The notice explicitly defines non-responsive applications: incremental tool improvements, projects primarily focused on social determinants of health, and projects primarily focused on ethical/legal/social issues. With NIH SBIR/STTR just reopened and the OMB Uniform Grants Regulation rewrite reshaping discretionary awards, the NLM clinical informatics line is one of the few stable, well-defined biomedical funding streams left at the agency. Here is how to read it.
Read articlePAR-28-027 was forecast on September 24, 2026: four awards, an $80,000 ceiling, a $10,000 floor, and a May 25, 2027 estimated deadline. The program's audience language changed between the expired PAR and the forecast, and the whole thing is a 19-month pipeline from forecast to first dollar.
Read articleDARPA pre-released Release 6 of its FY26 SBIR BAA on September 2, 2026. Five of the seven SBIR topics belong to the Biological Technologies Office, and four of those describe one continuous problem: keeping a casualty alive with no surgeon, no imaging, and no evacuation. Here are the award sizes, the Direct-to-Phase-II gates, and the sequencing DARPA is buying.
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