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NCI Community Oncology Research Program (NCORP) Research Bases (UG1 Clinical Trials Required) is sponsored by National Cancer Institute (NCI). This Notice of Funding Opportunity (NOFO) is one of three NOFOs for the National Cancer Institute (NCI) Community Oncology Research Program (NCORP).
NCORP is designed to enhance generalizability and dissemination of clinical trial and other human subject research study results through accrual in a variety of community settings. NCORP Research Bases will serve as the program's research hubs and are expected to provide scientific and statistical leadership for developing, implementing, and analyzing multi-institutional cancer control, prevention, and care delivery clinical research.
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gov Maintenance Calendar View similar opportunities NCI Community Oncology Research Program (NCORP) Research Bases (UG1 Clinical Trial Required) Department of Health and Human Services National Institutes of Health Document Type:Grants Notice Funding Opportunity Number:RFA-CA-27-006 Funding Opportunity Title:NCI Community Oncology Research Program (NCORP) Research Bases (UG1 Clinical Trial Required) Opportunity Category:Discretionary Opportunity Category Explanation: Funding Instrument Type:Cooperative Agreement Category of Funding Activity:Health Expected Number of Awards:7 Assistance Listings:93.
393 -- Cancer Cause and Prevention Research Cost Sharing or Matching Requirement:No Last Updated Date:May 21, 2026 Original Closing Date for Applications:Sep 18, 2026 Current Closing Date for Applications:Sep 18, 2026 Archive Date:Nov 18, 2026 Estimated Total Program Funding:$ 74,500,000 Eligible Applicants:Special district governments Public and State controlled institutions of higher education For profit organizations other than small businesses Others (see text field entitled "Additional Information on Eligibility" for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Private institutions of higher education Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Additional Information on Eligibility:Refer to Section III.
Eligibility Information in the NOFO for additional information on eligibility. Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.
Foreign components, as defined in the NIH Grants Policy Statement, are allowed. ## Additional Information Agency Name:National Institutes of Health Description:This Notice of Funding Opportunity (NOFO) is one of three NOFOs for the National Cancer Institute (NCI) Community Oncology Research Program (NCORP).
NCORP is designed to enhance generalizability and dissemination of clinical trial and other human subject research study results through accrual in a variety of community settings. The purpose of NCORP is to engage cancer patient populations, those at risk of cancer, and organizations in rigorous studies focused on cancer control, prevention, treatment and care delivery.
NCORP is a community-based research network that:Designs and conducts clinical trials and other human subject studies for adults and children in cancer control, prevention, screening, and care delivery, as well as quality-of-life studies embedded within treatment trials;Enhances patient and provider access to treatment and imaging trials conducted under the National Clinical Trials Network (NCTN);NCORP will support the following components that will be individually awarded through the respective Request for Applications (RFAs) indicated below:NCORP Research Bases (UG1 Clinical Trials Required)(covered by this NOFO);NCORP Community Sites (UG1 Clinical Trials Not Allowed); andNCORP Academic Community Sites (UG1 Clinical Trials Not Allowed).
NCORP Research Bases will serve as the program's research hubs and are expected to:Provide an established organizational structure, with scientific and statistical leadership for developing, implementing, and analyzing multi-institutional cancer control, prevention, and care delivery (CCP&CD) clinical research, as well as quality-of-life studies embedded in treatment and imaging studies.
Assume responsibility for study operations and data management, including efficient protocol development; compliance with Food and Drug Administration (FDA) and Office of Human Research Protections (OHRP) regulatory and participant protection requirements; auditing; training; quality assurance; and support to Community Sites and Academic Community Sites.
Be based at institutions with comprehensive cancer clinical research expertise (e.g., NCI-designated Cancer Center, or healthcare research organization – including NCI's National Clinical Trials Network (NCTN) Group Operations Centers, or a cancer foundation associated with a NCTN Group). Link to Additional Information:[](https://grants.
gov/search-results-detail/358963) Grantor Contact Information:If you have difficulty accessing the full announcement electronically, please contact: ## Similar Opportunities (identified by AI) #### Health & Human Services * Frequently Asked Questions ## Your session will expire in 3 minutes. To continue working, click on the "OK" button below. This is being done to protect your privacy.
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According to the current listing, eligibility includes: State governments; public and state controlled institutions of higher education; for-profit organizations other than small businesses; special district governments; Native American tribal governments (Federally recognized); public housing authorities/Indian housing authorities; nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; small businesses; Native American tribal organizations (other than Federally recognized tribal governments); private institutions of higher education; county governments; city or township governments; nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; independent school districts. Confirm the full requirements in the official notice before applying.
The current listing shows application budgets not capped; NCI to commit $74.5M in FY2027 for up to seven awards. Verify award ceilings, matching requirements, and allowable costs in the official notice.
The published deadline was September 18, 2026, which has passed. Check the official notice for any future application windows before investing time in a proposal.
NCI Community Oncology Research Program (NCORP) Research Bases (UG1 Clinical Trials Required) is funded by National Cancer Institute (NCI). Verify program details on the funder's official page before applying.
Applications go through the funder's official portal — the Apply Now link on this page goes there directly.
Past winners and funding trends for this program
On May 21, 2026, the National Cancer Institute posted RFA-CA-27-006, RFA-CA-27-007, and RFA-CA-27-008 — the three competitive renewals for the NCI Community Oncology Research Program. Combined FY 2027 commitments reach $147.5 million across roughly 57 awards: $74.5 million for up to 7 Research Bases, $73 million for up to 50 Community and Academic Community Sites. Pre-application webinars run June 16-18 this week. Applications are due August 18, 2026 with six-year project periods. For community hospitals, oncology consortia, and NCI-designated cancer centers, this is the single largest cancer clinical-trials infrastructure decision NCI makes until 2033.
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