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Find similar grantsNCI SBIR Small Business Transition Grant (R41/R42/R43/R44) is sponsored by National Cancer Institute (NCI). Targets early-career scientists transitioning from academia to entrepreneurship within a small business.
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Small Business Transition Grant - NCI NIH has no active Small Business Innovation Research (SBIR) or Small Business Technology Transfer (STTR) solicitations because the legislative authority for the programs expired on October 1, 2025. Current recipients should direct any questions to their Program Officer. See NOT-OD-26-006 .
Small Business Transition Grant Contact Saroj Regmi to learn more about this program. Notice Number: RFA-CA-24-023 The application period is closed. Please check back later.
View a recording of the informational webinar. Episode 13 | Small Business Transition Grant Listen to this podcast episode to hear the benefits of the Small Business Transition Grant from NCI SBIR Program Directors William Bozza and Saroj Regmi.
The Small Business Transition Grant aims to support early-career academic scientists interested in transitioning to entrepreneurship while also supporting the transfer of technology from academic laboratories into small businesses.
The scope of application must pertain to NCI’s mission and propose the development of a technology that fits into at least one of the following categories: Therapeutics and preventive agents Imaging technologies, interventional devices, and in vivo diagnostics In vitro and ex vivo diagnostics and prognostics The NCI SBIR transition grant proposes a new and unique Fast Track-only award structure made up of a Phase I STTR that transitions to a Phase II SBIR.
Awards made under this Notice of Funding Opportunity (NOFO) will begin as a Phase I STTR to allow the candidate to complete proof of concept studies at the academic site and prepare the technology to move into the small business.
After completion of the STTR Phase I activities, the transition to a Phase II SBIR award will occur only after meeting stringent criteria, including a demonstration of ongoing mentoring as well as having achieved technical milestones, including completion of the NIH I-Corps program. Note that small pivots in the project plan are allowed under Phase II SBIR funding. See Section V of the solicitation for more information.
As of this year’s Notice ( RFA-CA-24-023 ), the Small Business Transition Grant has also expanded to include a Phase I STTR-only option. A key component of the small business transition grant is mentoring. Mentoring is not traditionally a factor in SBIR/STTR funding decisions; however, for this grant, mentoring is critical to facilitate the transition from junior academic scientist to entrepreneur.
Therefore, the mentoring team who supports the candidate will be a critical factor in peer review. The ideal candidate for this small business transition grant is a postdoctoral researcher who participated in technology discovery during their academic work and is now ready to move to a small business with the help of some key mentors and advisors.
According to the current listing, eligibility includes: Small business concerns in partnership with a research institution (STTR) or as primary lead (SBIR). Confirm the full requirements in the official notice before applying.
The current listing shows up to $3,000,000 (Fast-Track). Verify award ceilings, matching requirements, and allowable costs in the official notice.
The most recent published deadline was April 6, 2026, which has passed. This is an annual program, so a new cycle should follow. Check the funder's website for the next application window.
NCI SBIR Small Business Transition Grant (R41/R42/R43/R44) is funded by National Cancer Institute (NCI). Verify program details on the funder's official page before applying.
Yes — this listing is flagged as national in scope, so applicants across the U.S. may apply, subject to the sponsor's other eligibility criteria.
Applications go through the funder's official portal — the Apply Now link on this page goes there directly.
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