New Generation of Glucose Control Technologies Incorporating AI/ML Tools/Strategies

New Generation of Glucose Control Technologies Incorporating AI/ML Tools/Strategies is a grant from the National Institutes of Health (NIH) that funds research advancing open- and closed-loop diabetes control systems.

Through the Special Diabetes Program (NIDDK), this R01 opportunity supports innovation in four focus areas: sensing of analytes and physiologic signals, novel hormone formulations and delivery, AI/ML-driven algorithms and decision-support tools, and digital twin modeling. The goal is to improve glycemic control, reduce care burden, and enhance quality of life for people with type 1 diabetes.

Eligible applicants include universities, nonprofits, for-profits, tribal governments, and foreign organizations. Clinical trial components are optional.

Opportunity Listing - New Generation of Glucose Control Technologies Incorporating AI/ML Tools/Strategies (R01 - Clinical Trial Optional) New Generation of Glucose Control Technologies Incorporating AI/ML Tools/Strategies (R01 - Clinical Trial Optional) Agency: National Institutes of Health Assistance Listings: 93.

847 -- Diabetes, Digestive, and Kidney Diseases Extramural Research Last Updated: May 13, 2026 View version history on Grants. gov The purpose of this funding opportunity is to support research addressing barriers that limit progress toward more effective open- and closed-loop diabetes control systems.

This may include research that addresses: 1) innovation of sensing relevant analytes/physiologic signals; 2) novel formulation and delivery of hormones; 3) artificial intelligence (AI)/machine learning (ML)-driven tools/algorithms; and 4) digital twin modeling to augment decision support and automated control systems with the goal of improving glycemic control, reducing burden of care, and enhancing quality of life of people...

with T1D]. This NOFO is associated with the Special Diabetes Program (https://www. niddk.

nih.

gov/about-niddk/research-areas/diabetes/type-1-diabetes-special-statutory-funding-program/about-special-diabetes-program) which funds research on the prevention, treatment, and cure of type 1 diabetes and its complications, including unique, innovative, and collaborative research consortia and clinical trials networks Public and Indian housing authorities Federally recognized Native American tribal governments City or township governments Special district governments For-profit organizations other than small businesses Other Native American tribal organizations Nonprofits non-higher education without 501(c)(3) Nonprofits non-higher education with 501(c)(3) Public and state institutions of higher education Private institutions of higher education Independent school districts Refer to Section III.

Eligibility Information in the NOFO for additional information on eligibility. Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are allowed. Grantor contact information Division of Diabetes, Endocrinology and Metabolic Diseases File name Description Last updated RFA-DK-27-146-Full-Announcement. html RFA-DK-27-146-Full-Announcement.

html Link to additional information Funding opportunity number : Cost sharing or matching requirement : Funding instrument type : Opportunity Category Explanation : Category of Funding Activity : Your account requires additional identity verification.