NHGRI Funding Opportunities (General Interest Areas)

NHGRI Funding Opportunities (General Interest Areas) is sponsored by National Human Genome Research Institute (NHGRI) - NIH. NHGRI funds grants that develop generalizable and broadly applicable resources, approaches, and technologies that accelerate and support studies focused on the structure and biology of genomes, identify the genomic underpinnings of human health and disease, and ensure that genom…

NIH Websites Are Changing Get the Latest Updates and FAQs The National Human Genome Research Institute supports research and training and career development opportunities in support of its research mission which is to accelerate scientific and medical breakthroughs that improve human health. We do this by driving cutting-edge research, developing new technologies, and studying the impact of genomics on society.

For how NHGRI will treat new and non-competing applications, see the NHGRI Funding Policy . For how NHGRI will treat new and non-competing applications, see the NHGRI Funding Policy .

Investigator Initiated Innovation in Computational Genomics and Data Science (R01 Clinical Trial Not Allowed): PAR-25-228 Application Due Dates: New: February 5, June 5 – 2025, 2026, 2027 Renewal/Resubmission/Revision: March 5, July 5 – 2025, 2026, 2027 Expiration date: September 8, 2027 Investigator Initiated Innovation in Computational Genomics and Data Science (R21 Clinical Trial Not Allowed): PAR-25-229 Application Due Dates: New: February 16, June 16 – 2025, 2026, 2027 Renewal/Resubmission/Revision: March 16, July 16 – 2025, 2026, 2027 Expiration date: September 8, 2027 Notice of Special Interest (NOSI): Small Business Solutions to Assist Genomics-Enabled Learning Health Systems (gLHS): NOT-HG-24-040 Notice of Special Interest (NOSI): Small Business Solutions to Enable Regional Genomic Medicine eConsult Services: NOT-HG-24-041 Notice of Special Interest (NOSI): Advancing Genomic Technology Development for Research and Clinical Application: NOT-HG-24-036 Ethical, Legal, and Social Implications (ELSI) Congress (U13, Clinical Trials Not Allowed) Application Due Date(s): November, 19, 2024 Expiration Date: November 20, 2024 Limited Competition: Building Partnerships and Broadening Perspectives to Advance Ethical, Legal, and Social Implications (ELSI) Research (BBAER) Program (UM1), Clinical Trial Optional Application Due Date(s): November 15, 2024, August 1, 2025, July 31, 2026 Expiration Date: August 3, 2026 Notice of Pre-Application Webinar for Limited Competition: Building Partnerships and Broadening Perspectives to Advance Ethical, Legal, and Social Implications (ELSI) Research (BBAER) Program (UM1, Clinical Trial Optional): NOT-HG-24-038 Advancing Genomic Medicine Research (R21 Clinical Trial Optional) Application Due Date(s): December 01, 2023, July 08, 2024, February 11, 2025 Expiration Date: February 12, 2025 SBIR Solutions to Enable Population Genomic Screening (R43/R44 Clinical Trial Optional) Application Due Date(s): December 2, 2024 Expiration Date: December 3, 2024 STTR Solutions to Enable Population Genomic Screening (R41/R42 Clinical Trial Optional) Application Due Date(s): December 2, 2024 Expiration Date: December 3, 2024 Population Genomic Screening in Primary Care Sequencing Center (U01 - Clinical Trial Optional) Application Due Date(s): December 2, 2024 Expiration Date: December 3, 2024 Population Genomic Screening in Primary Care Cooperative Agreement (U01 - Clinical Trial Required) Application Due Date(s): December 2, 2024 Expiration Date: December 3, 2024 Population Genomic Screening in Primary Care Coordinating Center (U01 -Clinical Trials Optional) Application Due Date(s): December 2, 2024 Expiration Date: December 3, 2024 Developing novel theory and methods for understanding the genetic architecture of complex human traits (R21 Clinical Trial Not Allowed) Application Due Date(s): February 16, 2024, June 16, 2024, October 16, 2024, February 16, 2025, June 16, 2025, October 16, 2025, February 16, 2026, June 16, 2026 and October 16, 2026 Expiration Date: January 8, 2027 Developing novel theory and methods for understanding the genetic architecture of complex human traits (R21 Clinical Trial Not Allowed) Application Due Date(s): February 16, 2024, June 16, 2024, October 16, 2024, February 16, 2025, June 16, 2025, October 16, 2025, February 16, 2026, June 16, 2026 and October 16, 2026 Expiration Date: January 8, 2027 Investigator-Initiated Research in Genomics and Health Equity (R01 Clinical Trial Optional) Application Due Date(s): November 08, 2023, July 08, 2024, July 08, 2025 (new); July 08, 2024 and July 08, 2025 (renewal) Expiration Date: July 09, 2025 Investigator-Initiated Research in Genomics and Health Equity (R21 Clinical Trial Optional) Application Due Date(s): November 08, 2023, July 08, 2024, July 08, 2025 (new); July 08, 2024 and July 08, 2025 (renewal) Expiration Date: July 09, 2025 Notice of Extension of the First Receipt Date of RFA-HG-23-018: Investigator-Initiated Research in Genomics and Health Equity (R21 Clinical Trial (Clinical Trial Optional): NOT-HG-24-008 Notice of Pre-Application Webinar for the Investigator-Initiated Research in Genomics and Health Equity: RFA-HG-23-017 (R01 Clinical Trial Optional) and RFA-HG-23-018 (R21 Clinical Trial Optional): NOT-HG-23-049 Notice of Change to NHGRI-specific language in RFA-HG-23-018, Investigator-Initiated Research in Genomics and Health Equity (R21 Clinical Trial Optional): NOT-HG-24-032 Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01 Clinical Trial Not Allowed) Application Due Dates: Applications are accepted by continuous receipt and are due by 5:00 PM local time of applicant organization.

Expiration Date: July 09, 2026 Notice of Intent to Publish a Funding Opportunity Announcement for Informatics Tools for the Pangenome (U01 Clinical Trial Not Allowed) : NOT-HG-23-028 Notice of Special Interest: Development and Implementation of Clinical Informatics Tools to Enhance Patients’ Use of Genomic Information NHGRI’s Analysis, Visualization, and Informatics Lab-space (AnVIL) as an NIH-Designated Data Repository: NOT-HG-24-020 Investigator Initiated Innovation in Computational Genomics and Data Science (R01 Clinical Trial Not Allowed): PAR-25-228 Application Due Dates: New: February 5, June 5 – 2025, 2026, 2027 Renewal/Resubmission/Revision: March 5, July 5 – 2025, 2026, 2027 Expiration date: September 8, 2027 Investigator Initiated Innovation in Computational Genomics and Data Science (R21 Clinical Trial Not Allowed): PAR-25-229 Application Due Dates: New: February 16, June 16 – 2025, 2026, 2027 Renewal/Resubmission/Revision: March 16, July 16 – 2025, 2026, 2027 Expiration date: September 8, 2027 Notice of Special Interest (NOSI): Small Business Solutions to Assist Genomics-Enabled Learning Health Systems (gLHS): NOT-HG-24-040 Notice of Special Interest (NOSI): Small Business Solutions to Enable Regional Genomic Medicine eConsult Services: NOT-HG-24-041 Notice of Special Interest (NOSI): Advancing Genomic Technology Development for Research and Clinical Application: NOT-HG-24-036 Ethical, Legal, and Social Implications (ELSI) Congress (U13, Clinical Trials Not Allowed) Application Due Date(s): November, 19, 2024 Expiration Date: November 20, 2024 Limited Competition: Building Partnerships and Broadening Perspectives to Advance Ethical, Legal, and Social Implications (ELSI) Research (BBAER) Program (UM1), Clinical Trial Optional Application Due Date(s): November 15, 2024, August 1, 2025, July 31, 2026 Expiration Date: August 3, 2026 Notice of Pre-Application Webinar for Limited Competition: Building Partnerships and Broadening Perspectives to Advance Ethical, Legal, and Social Implications (ELSI) Research (BBAER) Program (UM1, Clinical Trial Optional): NOT-HG-24-038 Advancing Genomic Medicine Research (R21 Clinical Trial Optional) Application Due Date(s): December 01, 2023, July 08, 2024, February 11, 2025 Expiration Date: February 12, 2025 SBIR Solutions to Enable Population Genomic Screening (R43/R44 Clinical Trial Optional) Application Due Date(s): December 2, 2024 Expiration Date: December 3, 2024 STTR Solutions to Enable Population Genomic Screening (R41/R42 Clinical Trial Optional) Application Due Date(s): December 2, 2024 Expiration Date: December 3, 2024 Population Genomic Screening in Primary Care Sequencing Center (U01 - Clinical Trial Optional) Application Due Date(s): December 2, 2024 Expiration Date: December 3, 2024 Population Genomic Screening in Primary Care Cooperative Agreement (U01 - Clinical Trial Required) Application Due Date(s): December 2, 2024 Expiration Date: December 3, 2024 Population Genomic Screening in Primary Care Coordinating Center (U01 -Clinical Trials Optional) Application Due Date(s): December 2, 2024 Expiration Date: December 3, 2024 Developing novel theory and methods for understanding the genetic architecture of complex human traits (R21 Clinical Trial Not Allowed) Application Due Date(s): February 16, 2024, June 16, 2024, October 16, 2024, February 16, 2025, June 16, 2025, October 16, 2025, February 16, 2026, June 16, 2026 and October 16, 2026 Expiration Date: January 8, 2027 Developing novel theory and methods for understanding the genetic architecture of complex human traits (R21 Clinical Trial Not Allowed) Application Due Date(s): February 16, 2024, June 16, 2024, October 16, 2024, February 16, 2025, June 16, 2025, October 16, 2025, February 16, 2026, June 16, 2026 and October 16, 2026 Expiration Date: January 8, 2027 Investigator-Initiated Research in Genomics and Health Equity (R01 Clinical Trial Optional) Application Due Date(s): November 08, 2023, July 08, 2024, July 08, 2025 (new); July 08, 2024 and July 08, 2025 (renewal) Expiration Date: July 09, 2025 Investigator-Initiated Research in Genomics and Health Equity (R21 Clinical Trial Optional) Application Due Date(s): November 08, 2023, July 08, 2024, July 08, 2025 (new); July 08, 2024 and July 08, 2025 (renewal) Expiration Date: July 09, 2025 Notice of Extension of the First Receipt Date of RFA-HG-23-018: Investigator-Initiated Research in Genomics and Health Equity (R21 Clinical Trial (Clinical Trial Optional): NOT-HG-24-008 Notice of Pre-Application Webinar for the Investigator-Initiated Research in Genomics and Health Equity: RFA-HG-23-017 (R01 Clinical Trial Optional) and RFA-HG-23-018 (R21 Clinical Trial Optional): NOT-HG-23-049 Notice of Change to NHGRI-specific language in RFA-HG-23-018, Investigator-Initiated Research in Genomics and Health Equity (R21 Clinical Trial Optional): NOT-HG-24-032 Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01 Clinical Trial Not Allowed) Application Due Dates: Applications are accepted by continuous receipt and are due by 5:00 PM local time of applicant organization.

Expiration Date: July 09, 2026 Notice of Intent to Publish a Funding Opportunity Announcement for Informatics Tools for the Pangenome (U01 Clinical Trial Not Allowed) : NOT-HG-23-028 Notice of Special Interest: Development and Implementation of Clinical Informatics Tools to Enhance Patients’ Use of Genomic Information NHGRI’s Analysis, Visualization, and Informatics Lab-space (AnVIL) as an NIH-Designated Data Repository: NOT-HG-24-020 Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 - Independent Clinical Trial Required) Application Due Date(s): October 12, 2024, February 12, 2025, June 12, 2025, October 12, 2025, February 12, 2026, June 12, 2026, October 12, 2026, February 12, 2027, June 12, 2027 Expiration Date: September 08, 2027 Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 Independent Clinical Trial Not Allowed) Application Due Date(s): October 12, 2024, February 12, 2025, June 12, 2025, October 12, 2025, February 12, 2026, June 12, 2026, October 12, 2026, February 12, 2027, June 12, 2027 Expiration Date: September 08, 2027 Change of Recipient Organization (Type 7 Parent Clinical Trial Optional) Application Due Date: A change of recipient organization request must be made before the anticipated start date at the new organization and preferably several months in advance.

Expiration Date: July 13, 2027 Successor-in-Interest (Type 6 Parent Clinical Trial Optional) Application Due Date: A successor-in-interest request must be made before the anticipated start date at the new organization and preferably several months in advance. Expiration Date: July 18, 2027 Ruth L.

Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31-Diversity) Application Due Date(s): December 08, 2023, April 08, 2024, August 08, 2024​​​​​​, December 08, 2024, April 08, 2025​​​​​​​, August 08, 2025 Expiration Date: September 08, 2025​​​​​​​ Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Required) Expiration Date: January 8, 2025 Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) Expiration Date: January 8, 2025 Plans to Promote Safe Environments at Conferences Supported by NIH Grants and Cooperative Agreements Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 - Independent Clinical Trial Required) Application Due Date(s): October 12, 2024, February 12, 2025, June 12, 2025, October 12, 2025, February 12, 2026, June 12, 2026, October 12, 2026, February 12, 2027, June 12, 2027 Expiration Date: September 08, 2027 Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 Independent Clinical Trial Not Allowed) Application Due Date(s): October 12, 2024, February 12, 2025, June 12, 2025, October 12, 2025, February 12, 2026, June 12, 2026, October 12, 2026, February 12, 2027, June 12, 2027 Expiration Date: September 08, 2027 Change of Recipient Organization (Type 7 Parent Clinical Trial Optional) Application Due Date: A change of recipient organization request must be made before the anticipated start date at the new organization and preferably several months in advance.

Expiration Date: July 13, 2027 Successor-in-Interest (Type 6 Parent Clinical Trial Optional) Application Due Date: A successor-in-interest request must be made before the anticipated start date at the new organization and preferably several months in advance. Expiration Date: July 18, 2027 Ruth L.

Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31-Diversity) Application Due Date(s): December 08, 2023, April 08, 2024, August 08, 2024​​​​​​, December 08, 2024, April 08, 2025​​​​​​​, August 08, 2025 Expiration Date: September 08, 2025​​​​​​​ Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Required) Expiration Date: January 8, 2025 Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) Expiration Date: January 8, 2025 Plans to Promote Safe Environments at Conferences Supported by NIH Grants and Cooperative Agreements NOT-OD-24-175 : Reporting Data Management and Sharing (DMS) Plan Activities in Research Performance Progress Reports (RPPRs) Submitted on or After October 1, 2024 NOT-OD-24-176 : Updated Processes for Requesting Revisions to an Approved Data Management and Sharing (DMS) Plan NOT-OD-25-003 : Reminder: Annual Reports to the Office of Laboratory Animal Welfare due December 1, 2024 NOT-OD-24-150 : Request for Information (RFI) on Recommendations on Re-envisioning U.S. Postdoctoral Research Training and Career Progression within the Biomedical Research Enterprise NOT-OD-24-084 : Overview of Grant Application and Review Changes for Due Dates on or after January 25, 2025 NOT-OD-24-163 : NIH’s Adoption of Common Forms for Biographical Sketch and Current and Pending (Other) Support by May 25, 2025 Building Sustainable Software Tools for Open Science (R03 Clinical Trial Not Allowed) Application Due Date(s): December 04,2024, June 04, 2025, December 04, 2025, June 04, 2026, December 04, 2026 Expiration Date: December 05, 2026 NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed) Application Due Date(s): December 04,2024, June 04, 2025, December 04, 2025, June 04, 2026, December 04, 2026 Expiration Date: December 05, 2026 NOT-TR-23-026 : Notice of Special Interest (NOSI): Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3) (Clinical Trial Optional) for Advancing Recruitment through Trial Innovation Network (AR-TIN) PAR-23-124 : Genomic Community Resources (U24 Clinical Trial Not Allowed) Application Due Date(s): May 25, 2023, September 25, 2023, January 25, 2024, September 25, 2024, January 25, 2025, September 25, 2025, January 25, 2026 Expiration Date: January 26, 2026 PAR-23-166 : Native American Research Centers for Health (NARCH) (S06 Clinical Trial Optional) Application Due Date(s): July 08, 2024, July 08, 2025, July 08, 2026 Expiration Date: August 08, 2026 NOT-OD-23-106 : Revising the NIH/AHRQ/NIOSH Post-Submission Material Policy PAR-23-138 : Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed) PAR-23-171 : Diagnostic Centers of Excellence (X01 Clinical Trial Not Allowed) Application Due Date(s): May 15, 2023, May 15, 2024, May 15, 2025 Expiration Date: May 16, 2025 The Intersection of Sex and Gender Influences on Health and Disease (R01 Clinical Trial Optional) Application Due Date(s): December 19, 2022, November 22, 2023; November 22, 2024 Expiration Date: November 23, 2024 Notice of Special Interest (NOSI): Research on the Health of Sexual and Gender Minority (SGM) Populations Dissemination and Implementation Research in Health (R01 Clinical Trial Optional) Application Due Date(s): June 15, 2022, October 05, 2022, February 05, 2023, June 05, 2023, June 05, 2023, February 05, 2024, June 05, 2024, October 05, 2024, February 05, 2025 Expiration Date: May 8, 2025 Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed) Application Due Date(s): June 16, 2022, October 16, 2022, February 16, 2023, June 16, 2023, October 16, 2023, February 16, 2024, June 16, 2024, February 16, 2025, June 16, 2025 Expiration Date: September 8, 2025 Dissemination and Implementation Research in Health (R21 Clinical Trial Optional) Application Due Date(s): June 16, 2022, October 16, 2022, February 16, 2023, June 16, 2023, October 16, 2023, February 16, 2024, June 16, 2024, October 16, 2024 Expiration Date: February 16, 2025 Notice of Special Interest (NOSI): Epidemiologic studies in Asian Americans, Native Hawaiians, and Pacific Islanders (Parent R01 Clinical Trial Not Allowed) NOT-HL-23-001 Administrative Supplements to Promote Diversity in Research and Development Small Businesses-SBIR/STTR (Admin Supp Clinical Trial Not Allowed) PA-21-345 Application Due Dates: Rolling Expiration Date: September 10, 2024 Announcing the High-Priority, Short-Term Project Award (R56) Notice of NHGRI's Participation in NOT-OD-04-047 "High Priority, Short-Term Project Award (R56)" NOT-HG-17-004 [grants.

nih.

gov] NOT-OD-24-175 : Reporting Data Management and Sharing (DMS) Plan Activities in Research Performance Progress Reports (RPPRs) Submitted on or After October 1, 2024 NOT-OD-24-176 : Updated Processes for Requesting Revisions to an Approved Data Management and Sharing (DMS) Plan NOT-OD-25-003 : Reminder: Annual Reports to the Office of Laboratory Animal Welfare due December 1, 2024 NOT-OD-24-150 : Request for Information (RFI) on Recommendations on Re-envisioning U.S. Postdoctoral Research Training and Career Progression within the Biomedical Research Enterprise NOT-OD-24-084 : Overview of Grant Application and Review Changes for Due Dates on or after January 25, 2025 NOT-OD-24-163 : NIH’s Adoption of Common Forms for Biographical Sketch and Current and Pending (Other) Support by May 25, 2025 Building Sustainable Software Tools for Open Science (R03 Clinical Trial Not Allowed) Application Due Date(s): December 04,2024, June 04, 2025, December 04, 2025, June 04, 2026, December 04, 2026 Expiration Date: December 05, 2026 NIH Research Software Engineer (RSE) Award (R50 Clinical Trials Not Allowed) Application Due Date(s): December 04,2024, June 04, 2025, December 04, 2025, June 04, 2026, December 04, 2026 Expiration Date: December 05, 2026 NOT-TR-23-026 : Notice of Special Interest (NOSI): Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3) (Clinical Trial Optional) for Advancing Recruitment through Trial Innovation Network (AR-TIN) PAR-23-124 : Genomic Community Resources (U24 Clinical Trial Not Allowed) Application Due Date(s): May 25, 2023, September 25, 2023, January 25, 2024, September 25, 2024, January 25, 2025, September 25, 2025, January 25, 2026 Expiration Date: January 26, 2026 PAR-23-166 : Native American Research Centers for Health (NARCH) (S06 Clinical Trial Optional) Application Due Date(s): July 08, 2024, July 08, 2025, July 08, 2026 Expiration Date: August 08, 2026 NOT-OD-23-106 : Revising the NIH/AHRQ/NIOSH Post-Submission Material Policy PAR-23-138 : Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed) PAR-23-171 : Diagnostic Centers of Excellence (X01 Clinical Trial Not Allowed) Application Due Date(s): May 15, 2023, May 15, 2024, May 15, 2025 Expiration Date: May 16, 2025 The Intersection of Sex and Gender Influences on Health and Disease (R01 Clinical Trial Optional) Application Due Date(s): December 19, 2022, November 22, 2023; November 22, 2024 Expiration Date: November 23, 2024 Notice of Special Interest (NOSI): Research on the Health of Sexual and Gender Minority (SGM) Populations Dissemination and Implementation Research in Health (R01 Clinical Trial Optional) Application Due Date(s): June 15, 2022, October 05, 2022, February 05, 2023, June 05, 2023, June 05, 2023, February 05, 2024, June 05, 2024, October 05, 2024, February 05, 2025 Expiration Date: May 8, 2025 Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed) Application Due Date(s): June 16, 2022, October 16, 2022, February 16, 2023, June 16, 2023, October 16, 2023, February 16, 2024, June 16, 2024, February 16, 2025, June 16, 2025 Expiration Date: September 8, 2025 Dissemination and Implementation Research in Health (R21 Clinical Trial Optional) Application Due Date(s): June 16, 2022, October 16, 2022, February 16, 2023, June 16, 2023, October 16, 2023, February 16, 2024, June 16, 2024, October 16, 2024 Expiration Date: February 16, 2025 Notice of Special Interest (NOSI): Epidemiologic studies in Asian Americans, Native Hawaiians, and Pacific Islanders (Parent R01 Clinical Trial Not Allowed) NOT-HL-23-001 Administrative Supplements to Promote Diversity in Research and Development Small Businesses-SBIR/STTR (Admin Supp Clinical Trial Not Allowed) PA-21-345 Application Due Dates: Rolling Expiration Date: September 10, 2024 Announcing the High-Priority, Short-Term Project Award (R56) Notice of NHGRI's Participation in NOT-OD-04-047 "High Priority, Short-Term Project Award (R56)" NOT-HG-17-004 [grants.

nih. gov] Expired Grant Application Solicitations and Notices FY2024 NHGRI Funding Policy Last updated: November 26, 2024