NIA Expanding Research in AD/ADRD (ERA) Summer Research Education Program (R25 Independent Clinical Trial Not Allowed)

NIA Expanding Research in AD/ADRD (ERA) Summer Research Education Program (R25 Independent Clinical Trial Not Allowed) is sponsored by National Institute on Aging (NIA) - NIH. This R25 program from NIA supports a summer research education program aimed at expanding research in Alzheimer's Disease and Related Dementias. It focuses on providing research education experiences for a minimum of 8 to a maximum of 14 weeks each year.

RFA-AG-26-011: NIA Expanding Research in AD/ADRD (ERA) Summer Research Education Program (R25 Independent Clinical Trial Not Allowed) Department of Health and Human Services Part 1.

Overview Information Participating Organization(s) National Institutes of Health ( NIH ) Components of Participating Organizations Funding Opportunity Title NIA Expanding Research in AD/ADRD (ERA) Summer Research Education Program (R25 Independent Clinical Trial Not Allowed) April 4, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25, 2025. See Notice NOT-OD-24-084 .

August 31, 2022 - Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023. See Notice NOT-OD-22-198 . August 5, 2022 - Implementation Details for the NIH Data Management and Sharing Policy.

See Notice NOT-OD-22-189 . July 22, 2019 - Requirement for ORCID iDs for Individuals Supported by Research Training, Fellowship, Research Education, and Career Development Awards Beginning in FY 2020. See Notice NOT-OD-19-109 .

Funding Opportunity Number (FON) Companion Funding Opportunity See Section III. 3. Additional Information on Eligibility .

Assistance Listing Number(s) Funding Opportunity Purpose The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH.

The overarching goal of this National Institute on Aging (NIA) R25 program is to support educational activities that compliment and/or enhance training opportunities to ensure a workforce that is well prepared to meet the nation’s biomedical, behavioral and clinical research needs, help recruit individuals with specific specialty or disciplinary backgrounds to research careers in biomedical, behavioral and clinical sciences and foster a better understanding of biomedical, behavioral and clinical research and its implications.

To accomplish the stated over-arching goal, this NOFO will support educational activities with a primary focus on: This Notice of Funding Opportunity (NOFO) invites R25 applications to support the development and implementation of summer research education programs for high school students, undergraduates, or science teachers.

It is essential to expand and broaden the skilled Alzheimer's Disease (AD) and Alzheimer’s Disease Related Dementias (ADRD) research workforce and provide exposure to AD/ADRD research to individuals early in their careers.

The proposed research education programs will support intensive summer research experiences in the AD/ADRD field with the goal of exposing participants to AD/ADRD research and encouraging further study or participation in biomedical and behavioral research. This NOFO does not allow participants to lead an independent clinical trial, but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor.

Funding Opportunity Announcement Goal(s) To encourage biomedical, social, and behavioral research and research training directed toward greater understanding of the aging process and the diseases, special problems, and needs of people as they age.

Open Date (Earliest Submission Date) Renewal / Resubmission / Revision (as allowed) AIDS - New/Renewal/Resubmission/Revision, as allowed All applications are due by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

No late applications will be accepted for this Notice of Funding Opportunity (NOFO). Required Application Instructions It is critical that applicants follow the instructions in the Research (R) Instructions in the How to Apply - Application Guide , except where instructed to do otherwise (in this NOFO or in a Notice from NIH Guide for Grants and Contracts ).

Conformance to all requirements (both in the How to Apply - Application Guide and the NOFO) is required and strictly enforced. Applicants must read and follow all application instructions in the How to Apply - Application Guide as well as any program-specific instructions noted in Section IV . When the program-specific instructions deviate from those in the How to Apply - Application Guide , follow the program-specific instructions.

Applications that do not comply with these instructions may be delayed or not accepted for review. There are several options available to submit your application through Grants. gov to NIH and Department of Health and Human Services partners.

You must use one of these submission options to access the application forms for this opportunity. Use the NIH ASSIST system to prepare, submit and track your application online. Use an institutional system-to-system (S2S) solution to prepare and submit your application to Grants.

gov and eRA Commons to track your application. Check with your institutional officials regarding availability. Workspace to prepare and submit your application and eRA Commons to track your application.

Part 1. Overview Information Part 2. Full Text of Announcement Section I.

Funding Opportunity Description Section II. Award Information Other Award Budget Information Section III. Eligibility Information Section IV.

Application and Submission Information Section V. Application Review Information Section VI. Award Administration Information Section VII.

Agency Contacts Section VIII. Other Information Part 2. Full Text of Announcement Section I.

Funding Opportunity Description The NIH Research Education Program (R25) supports research educational activities that complement other formal training programs in the mission areas of the NIH Institutes and Centers.

A major goal of the National Plan to address Alzheimer’s Disease (AD) and Alzheimer’s Disease-related Dementias (ADRD) is to reduce the burden of AD/ADRD by accelerating research toward treatments, improving care and support for people facing these conditions now, and reducing the risk of AD/ADRD by promoting brain health.

Despite this, there is a shortage of scientists conducting the wide variety of necessary innovative and interdisciplinary research projects, including basic biomedical, behavioral, clinical, translational, prevention, and treatment research on AD/ADRD. This Notice of Funding Opportunity (NOFO) aims to support the recruitment of early-stage investigators to the NIH AD/ADRD portfolio.

This NOFO also aims to address the lack of early exposure to high-quality, hands-on research education experiences in the AD/ADRD field, another major barrier to increasing the AD/ADRD capable workforce. To further expand the AD/ADRD research workforce pathways for earlier stage students, NIA will support summer research experiences for high school students, undergraduates, or science teachers.

The expectation is that such a program would incubate and develop the next generation of early-stage investigators to pursue research careers representative of NIA mission-critical areas, namely AD/ADRD research, including frontotemporal, Lewy body, and vascular dementia.

Proposed programs should provide authentic "open-ended", hands-on exposure to AD/ADRD research as it relates to aging as part of a comprehensive program based in sound educational practices designed to stimulate the interest and advance the knowledge base of participants.

In addition to hands-on research experiences, programs are expected to include complementary educational enrichment activities that support the participants' scientific development, such as relevant workshops (e.g., scientific writing and presentation skills), journal clubs, technical laboratory coursework, among other relevant activities.

Program goals and objectives should be grounded in literature and appropriate for the educational level of the audience to be reached, including the content to be conveyed, and the intended outcome(s). Outcomes for high school students may include preparing them for undergraduate admissions and enhancing their interest in pursuing a science decree.

Outcomes for college students may include reinforcing their intent to graduate with a science degree, preparing them for graduate or medical school admissions, and/or preparing them for careers in AD/ADRD research.

Support for science teachers will be limited to those programs with a clear plan for how teachers will utilize their summer experience in their teaching during the school year, such as enhancing the science, technology, engineering, and mathematics (STEM) curriculum or increasing number of STEM courses taught.

Focus on High School Students, Undergraduates, or Science Teachers : Science education research has demonstrated that early exposure to scientific research leads to the retention of trainees in STEM.

The President’s Council of Advisors on Science and Technology (PCAST) specifically highlights the need for retention of trainees in STEM by involving them in contemporary, hands-on research experiences especially during the first two years of college. Summer research experiences provide important experiential learning to sustain students’ interests in STEM and medicine careers.

The short-term summer experience, in contrast to a year-long experience, allows for a focused and concentrated effort on instruction, and intentionally coincides with the time of year when the target populations of this program (i.e., high school students, undergraduate college students, or science teachers) would typically have the opportunity to engage in such a research educational experience.

All programs are expected to provide opportunities for participants to interact with investigators who could contribute to their growth. Applications from a variety of institutions are encouraged. Applicants should consider how the developed programs can optimize participation and potentially include additional participants from outside the applicant institution, especially those in local and/or affiliated institutions.

Applicants must demonstrate how this program will add significant value over existing programs at the applicant institution. Each institution must have a unique program structure that maximizes resources, departments, and faculty at the applicant institution to address the target population. Applicants are encouraged to propose collaborations with affiliated and/or local institutions, as appropriate.

Applicants are also encouraged to partner with existing NIH-funded or other federally-funded resources and programs and leverage research education activities from both federal and private-sector partners including, but not limited to, the following: Alzheimer's Disease Research Centers (ADRCs) Centers on the Demography and Economics of Aging Claude D. Pepper Older Americans Independence Center (OAIC) Edward R.

Roybal Centers for Translation Research in the Behavioral and Social Sciences of Aging NCATS Clinical and Translational Science Awards (CTSA) Non-Responsiveness Criteria Applications that propose programs primarily outside of AD/ADRD research, or have a general STEM focus, will be considered non-responsive to this NOFO and will be withdrawn prior to review.

Research education programs may complement ongoing research training and education occurring at the applicant institution, but the proposed educational experiences must be distinct from those training and education programs currently receiving federal support. R25 programs may augment institutional research training programs (e.g., T32, T90), but cannot be used to replace or circumvent Ruth L.

Kirschstein National Research Service Award (NRSA) programs. See Section VIII. Other Information for award authorities and regulations.

Section II. Award Information Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity. Application Types Allowed The OER Glossary and the How to Apply - Application Guide provide details on these application types.

Only those application types listed here are allowed for this NOFO. Not Allowed: Only accepting applications that do not propose clinical trial(s). Note: Appointed participants are permitted to obtain research experience in a clinical trial led by a mentor or co-mentor.

Need help determining whether you are doing a clinical trial? Funds Available and Anticipated Number of Awards NIA intends to commit $1,000,000 respectively in FY 2027 and FY 2028 to fund up to 5 new awards each year. Direct costs up to $200,000 per year may be requested.

A project period of up to five years may be requested. Funds may be requested for a minimum of 8 weeks and a maximum of 14 weeks of research education experience each year. Other Award Budget Information Individuals designing, directing, and implementing the research education program may request salary and fringe benefits appropriate for the person months devoted to the program.

Salaries requested may not exceed the levels commensurate with the institution's policy for similar positions and may not exceed the congressionally mandated cap. (If mentoring interactions and other activities with participants are considered a regular part of an individual's academic duties, then any costs associated with the mentoring and other interactions with participants are not allowable costs from grant funds).

Participants may be compensated for participation in activities specifically required by the proposed research education program, if sufficiently justified. Participant costs must be itemized in the proposed budget. Allowable participant costs depend on the educational level/career status of the individuals to be selected to participate in the program.

Salary: High-school students and undergraduate students must be provided with salary and fringe benefits for the duration of the program consistent with institutional salary policies with justification. Science teachers can be provided with salary and fringe benefits up to $20,000 per science teacher.

Participants supported by other NIH training mechanisms such as the T-awards or other R25 education programs may not receive additional salary. Housing support to cover housing cost at the program site may be requested. Registration fees or tuition: Registration fees or tuition may not be charged for participation to this program.

Travel funds may be expended to cover the costs of travel between the place of residence and the training institution. Expenses may be requested for program-related expenses and travel to relevant scientific meetings that occur during the participant’s period of appointment.

Other Program-Related Expenses Consultant costs, equipment, supplies, travel for key persons, and other program-related expenses may be included in the proposed budget. These expenses must be justified as specifically required by the proposed program and must not duplicate items generally available at the applicant institution. Limited program evaluation costs are allowed up to a maximum of $3,000 per year.

This includes salaries for evaluation consultants, if any. Reasonable expenses per participant may be requested to support participant travel to the research site or to a domestic scientific conference.

Indirect Costs (also known as Facilities & Administrative [F&A] Costs) are reimbursed at 8% of modified total direct costs (exclusive of tuition and fees, expenditures for equipment and consortium costs in excess of $25,000), rather than on the basis of a negotiated rate agreement. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO. Section III.

Eligibility Information Higher Education Institutions - Includes all types Public/State Controlled Institutions of Higher Education Private Institutions of Higher Education Nonprofits Other Than Institutions of Higher Education Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education) Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education) For-Profit Organizations (Other than Small Businesses) City or Township Governments Special District Governments Indian/Native American Tribal Governments (Federally Recognized) Indian/Native American Tribal Governments (Other than Federally Recognized) U.S. Territory or Possession Independent School Districts Public Housing Authorities/Indian Housing Authorities Native American Tribal Organizations (other than Federally recognized tribal governments) Faith-based or Community-based Organizations The sponsoring institution must assure support for the proposed program.

Appropriate institutional commitment to the program includes the provision of adequate staff, facilities, and educational resources that can contribute to the planned program. Institutions with existing Ruth L.

Kirschstein National Research Service Award (NRSA) institutional training grants (e.g., T32) or other Federally funded training programs may apply for a research education grant provided that the proposed educational experiences are distinct from those training programs receiving federal support.

In many cases, it is anticipated that the proposed research education program will complement ongoing research training occurring at the applicant institution. Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement , are not allowed.

Applicant organizations must complete and maintain the following registrations as described in the How to Apply - Application Guide to be eligible to apply for or receive an award. All registrations must be completed prior to the application being submitted. Registration can take 6 weeks or more, so applicants should begin the registration process as soon as possible.

Failure to complete registrations in advance of a due date is not a valid reason for a late submission, please reference NIH Grants Policy Statement Section 2. 3. 9.

2 Electronically Submitted Applications for additional information. System for Award Management (SAM) – Applicants must complete and maintain an active registration, which requires renewal at least annually . The renewal process may require as much time as the initial registration.

SAM registration includes the assignment of a Commercial and Government Entity (CAGE) Code for domestic organizations which have not already been assigned a CAGE Code. NATO Commercial and Government Entity (NCAGE) Code – Foreign organizations must obtain an NCAGE code (in lieu of a CAGE code) in order to register in SAM. Unique Entity Identifier (UEI) – A UEI is issued as part of the SAM.

gov registration process. The same UEI must be used for all registrations, as well as on the grant application. eRA Commons - Once the unique organization identifier is established, organizations can register with eRA Commons in tandem with completing their Grants.

gov registration; all registrations must be in place by time of submission. eRA Commons requires organizations to identify at least one Signing Official (SO) and at least one Program Director/Principal Investigator (PD/PI) account in order to submit an application. Grants.

gov – Applicants must have an active SAM registration in order to complete the Grants. gov registration. Program Directors/Principal Investigators (PD(s)/PI(s)) All PD(s)/PI(s) must have an eRA Commons account.

PD(s)/PI(s) should work with their organizational officials to either create a new account or to affiliate their existing account with the applicant organization in eRA Commons. If the PD/PI is also the organizational Signing Official, they must have two distinct eRA Commons accounts, one for each role. Obtaining an eRA Commons account can take up to 2 weeks.

Eligible Individuals (Program Director/Principal Investigator) Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) is invited to work with their organization to develop an application for support.

For institutions/organizations proposing multiple PDs/PIs, visit the Multiple Program Director/Principal Investigator Policy and submission details in the Senior/Key Person Profile (Expanded) Component of the How to Apply - Application Guide .

The PD/PI should be an established investigator in the scientific area in which the application is targeted and capable of providing both administrative and scientific leadership to the development and implementation of the proposed program. The PD/PI will be expected to monitor and assess the program and submit all documents and reports as required.

NIA encourages multiple PD(s)/PI(s), particularly when each brings a unique perspective and skill set that will enhance the research education program. The PD(s)/PI(s) must be able to provide both administrative and scientific leadership to the development and implementation of the proposed program.

At least one of the PD(s)/PI(s) should be an investigator with an active research program in an AD/ADRD-related discipline (e.g., as demonstrated by recent publications and current research support).

Additional PD(s)/PI(s), including individuals with experience in the science of education, relevant social science disciplines, program evaluation, mentoring, experience in expanding and broadening participation in the AD/ADRD research workforce, or university administration may be included to achieve the program goals. Any of the PD(s)/PI(s) may serve as the contact PD/PI.

This NOFO does not require cost sharing as defined in the NIH Grants Policy Statement Section 1. 2 Definition of Terms . 3.

Additional Information on Eligibility Applicant organizations may submit more than one application, provided that each application is scientifically distinct. NIH will not accept duplicate or highly overlapping applications under review at the same time per NIH Grants Policy Statement Section 2. 3.

7. 4 Submission of Resubmission Application . This means that the NIH will not accept: A new (A0) application that is submitted before issuance of the summary statement from the review of an overlapping new (A0) or resubmission (A1) application.

A resubmission (A1) application that is submitted before issuance of the summary statement from the review of the previous new (A0) application. An application that has substantial overlap with another application pending appeal of initial peer review. ( see NIH Grants Policy Statement 2.

3. 9. 4 Similar, Essentially Identical, or Identical Applications ) No more than two applications are allowed per institution.

If two applications are submitted, then the two awards must be for different target groups. Researchers from a variety of scientific backgrounds are encouraged to participate as preceptors/mentors. Mentors should have research expertise and experience relevant to the proposed program.

Mentors must be committed to continue their involvement throughout the total period of the mentee’s participation in this award. Unless strongly justified on the basis of exceptional relevance to NIH, research education programs should be used primarily for the education of U.S. citizens and permanent residents. Section IV.

Application and Submission Information 1. Requesting an Application Package The application forms package specific to this opportunity must be accessed through ASSIST, Grants. gov Workspace or an institutional system-to-system solution.

Links to apply using ASSIST or Grants. gov Workspace are available in Part 1 of this NOFO. See your administrative office for instructions if you plan to use an institutional system-to-system solution.

2. Content and Form of Application Submission It is critical that applicants follow the instructions in the Research (R) Instructions in the How to Apply - Application Guide , except where instructed in this Notice of Funding Opportunity to do otherwise. Conformance to the requirements in the How to Apply - Application Guide is required and strictly enforced.

Applications that are out of compliance with these instructions will not be reviewed. Although a letter of intent is not required, is not binding, and does not enter into the review of a subsequent application, the information that it contains allows IC staff to estimate the potential review workload and plan the review. By the date listed in Part 1.

Overview Information , prospective applicants are asked to submit a letter of intent that includes the following information: Descriptive title of proposed activity Name(s), address(es), and telephone number(s) of the PD(s)/PI(s) Names of other key personnel Participating institution(s) Number and title of this funding opportunity The letter of intent should be sent to: National Institute on Aging (NIA) All page limitations described in the How to Apply - Application Guide and the Table of Page Limits must be followed.

Instructions for Application Submission The following section supplements the instructions found in the How to Apply - Application Guide and should be used for preparing an application to this NOFO. Follow all instructions provided in the How to Apply - Application Guide . SF424(R&R) Project/Performance Site Locations Follow all instructions provided in the How to Apply - Application Guide .

SF424(R&R) Other Project Information Component Follow all instructions provided in the How to Apply - Application Guide with the following additional modifications: Facilities & Other Resources. Describe the educational environment, including the facilities, laboratories, participating departments, computer services, and any other resources to be used in the development and implementation of the proposed program.

List all thematically related sources of support for research training and education following the format for Current and Pending Support. Appropriate institutional commitment should include the provision of adequate staff, facilities, and educational resources that can contribute to the planned research education program.

Advisory Committee: While not required, an Advisory Committee may be useful in structuring and evaluating the program. Please include a plan for the appointment of an Advisory Committee to monitor progress of the research education program, if applicable. The composition, roles, responsibilities, and desired expertise of committee members, frequency of committee meetings, and other relevant information should be included.

Describe how the Advisory Committee will evaluate the overall effectiveness of the program. New applications should not include the names of proposed Advisory Committee members, and proposed members should not be contacted prior to peer review. Please name your file “Advisory_Committee.

pdf”. Program Faculty Biosketches : Biosketches of Program Faculty must be included. The personal statement should describe a commitment to scientific rigor, training, mentoring, as well as promoting supportive scientific environments.

Please upload all of the biosketches as a single PDF and name your file “Program Faculty Biosketches. pdf”. The filename provided for each “Other Attachment” will be the name used for the bookmark in the electronic application in eRA Commons.

SF424(R&R) Senior/Key Person Profile Expanded Follow all instructions provided in the How to Apply - Application Guide . Describe the qualifications of the PD(s)/PI(s), collaborators, and other researchers without duplicating information in the biographical sketches. Describe the experience and training of key personnel in the early stages of their independent careers.

Describe the ongoing record of accomplishments of established investigators that have advanced their field(s). Senior/Key Personnel profiles must collectively reflect strong evidence of the following: The ability of the PD(s)/PI(s) to provide both administrative and scientific leadership to the development and implementation of the proposed program.

An appropriate level of effort will be devoted by the program leadership to ensure the program's intended goal is accomplished. If the project is collaborative or multi-PD/PI, the investigators' complementary and integrated expertise, leadership approach, governance, and organizational structure as appropriate for the proposed project.

Follow all instructions provided in the How to Apply - Application Guide with the following additional modifications: Include all personnel other than the PD(s)/PI(s) in the Other Personnel section, including clerical and administrative staff. Use the section on Participant/Trainee Support Costs to include all allowable categories of funds requested to support participants in the program.

PHS 398 Cover Page Supplement Follow all instructions provided in the How to Apply - Application Guide .

All instructions in the How to Apply - Application Guide must be followed, with the following additional instructions: Research Strategy section must be used to upload the Research Education Program Plan , which must include the following components described below: Proposed Research Education Program Program Director/Principal Investigator Institutional Environment and Commitment Plan for Instruction in the Responsible Conduct of Research Research Education Program Plan Proposed Research Education Program.

While the proposed research education program may complement ongoing research training and education occurring at the applicant institution, the proposed educational experiences must be distinct from those research training and research education programs currently receiving federal support.

When research training programs are on-going in the same department, the applicant organization should clearly distinguish between the activities in the proposed research education program and the research training supported by the training program.

Program Rationale, Mission, Objectives, and Overall Research Education Plan: Applications must include the rationale for the proposed NIA ERA program as well as the feasibility of success in the context of the institutional setting. Describe and summarize relevant institutional and externally sponsored programs at the participating institution within the last five years.

Specifically, the application should describe the following: The goals and objectives of the proposed research experience program and how they address the NIA mission with respect to AD/ADRD must be justified.

Each program, depending on whether the target group is high-school students, college-students, or science teachers, must describe the innovative aspects and the significance of the research experience program as well as the educational concepts and principles on which the program is based. Overall didactic philosophy, strategy, and concepts must be clearly articulated.

The activities that support the participants' scientific development, such as scientific writing and presentation skills. Each program must describe the feasibility of the proposed activities and how they relate to the strengths of the institution and describe the benchmarks to be used to assess the success of the research experiences program.

Potential problems that may be encountered and describe alternative strategies that could be employed. The application must describe and justify the timeline for the overall Research Education Program Plan.

Professional Development : The application should describe how the program participants will: For high school students: Enhance their interest in college level STEM education as well as increase their understanding of the skills, knowledge, and steps needed to attain positions in the sectors of the AD/ADRD research workforce that are of interest to them.

For undergraduates: Increase their interest and retention in STEM degrees and their interest in graduate level science education or scientific careers related to AD/ADRD. For science teachers: Enhance teachers’ scientific knowledge base and allow them to develop hands-on scientific curriculum focused on AD/ADRD.

Program Oversight, Participating Faculty Selection, and Mentor Training: The application must include the planned strategy and administrative structure to oversee and monitor the program and to ensure appropriate participant progress.

All programs must describe a mechanism to monitor mentoring, including oversight of the effectiveness of the participant/faculty match, and a plan for removing faculty displaying unacceptable mentorship qualities from the research education program. If a program will utilize an Advisory Committee for oversight, provide details in the Advisory Committee attachment.

If a program coordinator or administrator position is planned to enhance oversight, a description of the person's administrative capabilities that are essential to coordinate the program must be included in the application. Program Director/Principal Investigator. Describe arrangements for administration of the program.

Provide evidence that the Program Director/Principal Investigator is actively engaged in research and/or teaching in an area related to the mission of NIH, and can organize, administer, monitor, and evaluate the research education program. For programs proposing multiple PDs/PIs, describe the complementary and integrated expertise of the PDs/PIs, their leadership approach, and governance appropriate for the planned project.

NIA encourages multiple PD(s)/PI(s) (MPI), particularly when each brings a unique perspective and skill set that will enhance the research education program as described in the Eligible Individuals section above.

The application must expand on the information in the biosketch(es) to address how the PD/PI or PD/PI team has the following: The administrative and training experience and skills to provide strong leadership, direction, management, and administration of the proposed research education program; The time to commit sufficient effort to ensure the program’s success given other professional obligations (the application should indicate the program director’s effort in person months in the proposed program); At least one member who has scientific expertise in AD/ADRD and who has a record of using rigorous and transparent methods in experimental design, data collection, analysis, and reporting; A demonstrated commitment to the development of the next generation of AD/ADRD research workforce, leading efforts to expand and broaden participation in biomedical and behavioral sciences, and fostering supportive research environments.

The PD(s)/PI(s) must receive training on how to effectively mentor high school, undergraduate, or science teacher participants. The administrative structure and leadership succession plan for critical positions (e.g., PD(s)/PI(s)). Program Faculty.

Researchers from a variety of scientific backgrounds are encouraged to participate as program faculty. Faculty should have research expertise and experience relevant to the proposed program and demonstrate a history of, or the potential for, their intended roles. The application must address the following: Whether the participating faculty have sufficient time to