Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15)

Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15) is sponsored by National Institute on Aging (NIA) - NIH. This program supports small-scale research grants with an emphasis on providing biomedical research experiences primarily for health professional and graduate students, and enhancing the research environment at applicant institutions.

PAR-25-298: Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission. Department of Health and Human Services Part 1.

Overview Information Participating Organization(s) National Institutes of Health ( NIH ) Components of Participating Organizations National Institute of Dental and Craniofacial Research ( NIDCR ) National Eye Institute ( NEI ) National Heart, Lung, and Blood Institute ( NHLBI ) National Human Genome Research Institute ( NHGRI ) National Institute on Alcohol Abuse and Alcoholism ( NIAAA ) National Institute of Allergy and Infectious Diseases ( NIAID ) National Institute of Arthritis and Musculoskeletal and Skin Diseases ( NIAMS ) National Institute of Biomedical Imaging and Bioengineering ( NIBIB ) Eunice Kennedy Shriver National Institute of Child Health and Human Development ( NICHD ) National Institute on Deafness and Other Communication Disorders ( NIDCD ) National Institute on Drug Abuse ( NIDA ) National Institute of Environmental Health Sciences ( NIEHS ) National Institute of Mental Health ( NIMH ) National Institute of Neurological Disorders and National Institute of Nursing Research ( NINR ) National Center for Complementary and Integrative Health ( NCCIH ) Division of Program Coordination, Planning and Strategic Initiatives, Office of Research Infrastructure Programs ( ORIP ) National Cancer Institute ( NCI ) Funding Opportunity Title Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) R15 Research Enhancement Award Program (REAP) Notices of Special Interest associated with this funding opportunity January 28, 2026 - NIH Removing AIDS Application Due Dates from NOFOs.

See Notice NOT-OD-26-029 . March 31, 2025 - This funding opportunity was updated to align with agency priorities. Carefully reread the full funding opportunity and make any needed adjustments to your application prior to submission.

April 4, 2024 - Overview of Grant Application and Review Changes for Due Dates on or after January 25, 2025. See Notice NOT-OD-24-084 . August 31, 2022 - Implementation Changes for Genomic Data Sharing Plans Included with Applications Due on or after January 25, 2023.

See Notice NOT-OD-22-198 . August 5, 2022 - Implementation Details for the NIH Data Management and Sharing Policy. See Notice NOT-OD-22-189 .

Funding Opportunity Number (FON) Companion Funding Opportunity Research Enhancement Awards (REA) Research Enhancement Awards (REA) See Section III. 3. Additional Information on Eligibility .

Assistance Listing Number(s) 93. 121, 93. 867, 93.

173, 93. 286, 93. 242, 93.

865, 93. 279, 93. 351, 93.

846, 93. 393, 93. 394, 93.

395, 93. 396, 93. 399, 93.

213, 93. 361, 93. 853, 93.

113, 93. 273, 93. 837, 93.

233, 93. 838, 93. 839, 93.

840, 93. 866, 93. 172, 93.

855 Funding Opportunity Purpose The purpose of the Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools is to support small scale research grants at institutions that do not receive substantial funding from the NIH, with an emphasis on providing biomedical research experiences primarily for health professional, undergraduate and graduate students and enhancing the research environment at applicant institutions.

Eligible institutions must award baccalaureate or advanced science degrees and have received no more than $6 million dollars per year of NIH support (in both direct and F&A/indirect costs) in 4 of the last 7 fiscal years. For institutions composed of multiple schools and colleges, the $6 million funding limit is based on the amount of NIH funding received by all the schools and colleges within the institution as a whole.

Help determining the Organization Funding Level can be found here or https://grants. nih. gov/grants/funding/r15.

htm . Funding Opportunity Announcement Goal(s) NIH’s mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability. Open Date (Earliest Submission Date) The following table includes NIH standard due dates marked with an asterisk.

Renewal / Resubmission / Revision (as allowed) AIDS - New/Renewal/Resubmission/Revision, as allowed All applications are due by 5:00 PM local time of applicant organization. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

Required Application Instructions It is critical that applicants follow the instructions in the Research (R) Instructions in the How to Apply - Application Guide , except where instructed to do otherwise (in this NOFO or in a Notice from NIH Guide for Grants and Contracts ). Conformance to all requirements (both in the Application Guide and the NOFO) is required and strictly enforced.

Applicants must read and follow all application instructions in the Application Guide as well as any program-specific instructions noted in Section IV. When the program-specific instructions deviate from those in the Application Guide, follow the program-specific instructions. Applications that do not comply with these instructions may be delayed or not accepted for review.

There are several options available to submit your application through Grants. gov to NIH and Department of Health and Human Services partners. You must use one of these submission options to access the application forms for this opportunity.

Use the NIH ASSIST system to prepare, submit and track your application online. Use an institutional system-to-system (S2S) solution to prepare and submit your application to Grants. gov and eRA Commons to track your application.

Check with your institutional officials regarding availability. Workspace to prepare and submit your application and eRA Commons to track your application. Part 1.

Overview Information Part 2. Full Text of Announcement Section I. Notice of Funding Opportunity Description Section II.

Award Information Section III. Eligibility Information Section IV. Application and Submission Information Section V.

Application Review Information Section VI. Award Administration Information Section VII. Agency Contacts Section VIII.

Other Information Part 2. Full Text of Announcement Section I. Notice of Funding Opportunity Description The National Institutes of Health (NIH) is continuing to make a special effort to stimulate research at educational institutions that provide baccalaureate and/or advanced degrees for a significant number of the Nation's research institutions that have not been major recipients of NIH support.

Since Fiscal Year (FY) 1985 Congressional appropriations for the NIH have included funds for this initiative, known as the Academic Research Enhancement Award (AREA) program that was intended to focus on undergraduate institutions (PAR-25-134).

To complement the AREA program, this notice of funding opportunity (NOFO) specifically supports eligible health professional schools and graduate schools, along with undergraduate schools to provide research experiences to health professional, undergraduate and/or graduate students pursuing biomedical or behavioral research.

The three objectives of this NOFO are to: (1) provide support for meritorious research; (2) strengthen the research environment at these institutions; and (3) give health professional, undergraduate and/or graduate students an opportunity to gain significant biomedical research experience through active involvement in the research.

The REAP program will enable eligible institutions to receive support for small-scale research projects led by faculty members.

It is anticipated that investigators supported under the REAP program will benefit from the opportunity to conduct independent research; that the recipient institution will benefit from a research environment strengthened through REAP grants; and that students at recipient institutions will benefit from exposure to and participation in scientific research in the biomedical sciences and be inspired to consider careers in biomedical research.

The REAP NOFO emphasizes the engagement of health professional, undergraduates and/or graduate students in research. The research project must involve health professional, undergraduate and/or graduate students and the research team must be composed primarily of health professional, undergraduate and/or graduate students.

Student involvement in research may include participation in the design of experiments and controls, collection and analysis of data, execution and troubleshooting of experiments, presenting at meetings, drafting journal articles, participation in lab meetings to discuss results and future experiments, etc. The REAP is a research grant program, not a training or fellowship program.

As such, applications should not include training plans such as didactic training or non-research activities relating to professional development. This NOFO does not provide support for research at undergraduate-focused institutions, and investigators from those institutions should apply to PAR-25-134 Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed).

Additional information on R15 programs can be found at: NIH Research Enhancement Award (R15) . A REAP application submitted to this NOFO may include other investigators, such as technicians, collaborators, consultants, or other individuals such as high school students, post baccalaureate participants, postdoctoral fellows, or clinical fellows.

However, the involvement of such individuals does not fulfill the goal of engaging health professional, undergraduate and/or graduate students at eligible institutions. This NOFO will support basic and/or human subjects research but will NOT support research meeting the NIH definition of a clinical trial.

Applicants are strongly encouraged to refer to NIH guidance on clinical trials ( Clinical Trial Requirements for Grants and Contracts ) or consult with NIH staff before applying. In addition, applicants are encouraged to consult the Frequently Asked Questions website and the NIH Research Enhancement Award R15 website for more information about this program. Participating NIH Institutes and Centers are indicated in Part 1.

Overview "Components of Participating Organizations". For additional scientific program information and for pre-application guidance, applicants are encouraged to contact the person listed for the participating NIH IC(s) with research interests relevant to the applicant's proposed topic. Consultation with relevant NIH staff prior to the application due date is strongly encouraged for new and resubmission applications.

See Section VII. for contact information. Institute/Center Specific Interests National Heart, Lung, and Blood Institute ( NHLBI ) The NHLBI supports basic and clinical research pertaining to the structure, function, and diseases of the cardiovascular system, lungs, blood and blood vessels, and sleep disorders.

NHLBI supports clinical trial research that is mechanistic and/or efficacy focused, including behavioral, pharmacotherapeutic, device-based, and other intervention approaches. The NHLBI also supports research in stem cell biology and transplantation, transfusion medicine, and blood resources.

The NHLBI carries out its mission through a number of research programs that provide support for projects ranging from studies at the molecular level to whole body studies in man and animals.

Examples of research areas supported by the NHLBI include atherosclerosis, hypertension, cerebrovascular disease (directed at the dependent variable of blood, heart, or blood vessel), coronary heart disease, peripheral vascular diseases, arrhythmias, heart failure, and shock, congenital and rheumatic heart diseases, cardiomyopathies and infections of the heart, circulatory assistance, lung cell and molecular biology, chronic obstructive lung diseases, pediatric pulmonary diseases, cystic fibrosis, sleep-disordered breathing, asthma, fibrotic and immunologic lung diseases, acute respiratory failure, pulmonary vascular diseases, HIV-associated lung disorders and bone marrow suppression, bleeding and clotting disorders, disorders of the red blood cell such as sickle cell disease and Cooley's anemia, bone marrow failure syndromes, and blood resources.

National Human Genome Research Institute ( NHGRI) NHGRI supports the development of resources, approaches, and technologies that will accelerate genomic research on the structure of genomes, the biology of genomes, and the biology of disease; that will use genomics to advance the science of medicine; and that will incorporate genomics to improve the effectiveness of healthcare.

NHGRI also supports genomic research in several cross-cutting areas, including the ethical, legal and societal implications of genomics and genetics research, bioinformatics, technology development, and research training and career development. In general, NHGRI supports studies that provide generalizable methods and knowledge.

Applications for studies relevant only to a particular disease or organ system should be directed to the appropriate Institute or Center. NHGRI strongly encourages potential applicants to reach out to the listed scientific contact in the early stages of developing an application.

National Institute on Aging ( NIA ) NIA will accept applications for research projects in areas within the Institute's mission that includes genetic, biological, behavior, social, and economic research on aging. In addition, NIA encourages applications on Alzheimer’s Disease (AD) and AD Related Dementias (ADRD). The NIA website ( https://www.

nia. nih. gov/ ) provides additional information.

about the Institute mission and areas of research interest. For additional scientific program information and for pre-application guidance, a potential applicant is encouraged to contact the NIA Program Director ( link ) whose portfolio covers the scientific topic of interest.

National Institute of Alcohol Abuse and Alcoholism ( NIAAA ) National Institute of Allergy and Infectious Diseases ( NIAID ) NIAID supports basic and applied research to better understand, treat, and prevent infectious, immunologic, and allergic diseases, with the goal of developing new therapies, vaccines, diagnostic tests, and other technologies.

Research areas include microbiology and infectious diseases, AIDS and AIDS -related research, immunology, allergy, transplantation, radiation medical countermeasures,and biodefense.

National Institute of Arthritis and Musculoskeletal and Skin Diseases ( NIAMS ) NIAMS supports research into the causes, treatment, and prevention of arthritis and musculoskeletal and skin diseases; the training of basic and clinical scientists to carry out this research; and the dissemination of information on research progress in these diseases.

NIAMS also conducts and supports basic research on the normal structure and function of bones, joints, muscles, and skin. Basic research involves a wide variety of scientific disciplines, including immunology, genetics, molecular biology, structural biology, biochemistry, physiology, virology, and pharmacology.

Clinical research includes rheumatology, orthopedics, dermatology, metabolic bone diseases, heritable disorders of bone and cartilage, inherited and inflammatory muscle diseases, and sports and rehabilitation medicine. NIAMS will accept applications for research projects in areas within the Institute's mission. The NIAMS website ( https://www.

niams. nih. gov/ ) provides information about the institute mission and areas of research interest ( https://www.

niams. nih. gov/about-niams/strategic-plan-fiscal-years-2020-2024 ).

For additional scientific program information and for pre-application guidance, potential applicants are encouraged to contact the NIAMS Extramural Research Program Staff whose portfolio covers the scientific topic of interest ( https://www. niams. nih.

gov/grants-funding/funding-opportunities/supported-scientific-areas ). National Institute of Biomedical Imaging and Bioengineering ( NIBIB ) The mission of the National Institute of Biomedical Imaging and Bioengineering (NIBIB) is to improve human health by supporting the development of cutting-edge technologies and computational methods in Biomedical imaging and Bioengineering.

NIBIB-funded innovations have broad impact and fundamentally change our ability to prevent, diagnose, and treat human disease. Under this FOA, NIBIB will fund research projects that can be generalized to multiple conditions and physiological contexts and that fall under one or more of its Scientific Program Areas.

Eunice Kennedy Shriver National Institute of Child Health and Human Development ( NICHD ) The NICHD supports biological, behavioral, and clinical research related to conception and pregnancy, normal and abnormal development in childhood, reproductive health, population dynamics across the lifespan, and rehabilitation medicine. https://www. nichd.

nih. gov/grants-funding/opportunities-mechanisms/areas-research/Pages/default. aspx .

Research projects considered by funding by NICHD must fall within the scientific missions of the twelve Scientific Branches of the NICHD Division of Extramural Research (DER) or the National Center for Medical Rehabilitation Research (NCMRR). Information about those scientific missions and program staff contacts may be found on the web pages for the DER scientific branches at: http://www. nichd.

nih. gov/about/org/der/branches/Pages/index. aspx and the NCMRR at: http://www.

nichd. nih. gov/about/org/ncmrr/Pages/overview.

aspx . Potential applicants are strongly encouraged to read these webpages for any updates in response to recent scientific advances or emerging public health topics. NICHD encourages applications that address its extramural program priorities and will consider how well research projects align with one or more of those priorities when making award decisions.

A detailed list of NICHD high priority research areas may be found at https://www. nichd. nih.

gov/grants-funding/opportunities-mechanisms/areas-research/Pages/priorities. asp . National Institute on Deafness and other Communication Disorders ( NIDCD ) NIDCD supports applications that proposes research projects in the normal and disordered processes of hearing, balance, taste, smell, voice, speech, and language.

Applicants are strongly encouraged to learn more about NIDCD research areas at https://www. nidcd. nih.

gov/research/extramural . National Institute of Dental and CraniofacialResearch ( NIDCR ) NIDCR supports research concerning the etiology, epidemiology, prevention, diagnosis, and treatment of dental, oral and craniofacial disorders and diseases.

In this context, the NIDCR emphasizes research on caries and periodontal diseases; oral infections (viral, fungal, and bacterial) host-responses to oral infections, (e.g., innate and adaptive immune responses), biofilms and microbial ecology, genomics and proteomics; oral aspects of AIDS/HIV infection; head and neck cancers; craniofacial development, physiology and malformations; orofacial pain and other oral sensory and motor dysfunctions; salivary glands and disorders such as Sjögren's disease; temporomandibular joint disorders; and restoration and regeneration of dental, oral and craniofacial structures.

National Institute of Drug Abuse ( NIDA ) National Institute of Environmental Health Sciences ( NIEHS ) National Institute for Mental Health ( NIMH ) The National Institute of Neurological Disorders and Stroke ( NINDS ) NINDS seeks fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease.

NINDS supports basic, translational and clinical research within specifically defined areas of neuroscience. Research projects considered for funding by NINDS must fall within the scientific research mission of the Institute.

Applicants are strongly encouraged to contact the person listed under Agency Contacts (Section VII) early in the application preparation process to confirm the relevance of the proposed research to the NINDS mission and for preapplication guidance.

National Institute of Nursing Research ( NINR ) The National Institute of Nursing Research (NINR) supports research that builds the scientific foundation for nursing practice and policy across clinical and community settings, and advances the prevention, detection, and management of disease and disability.

Drawing on nursing’s holistic perspective, NINR funds research that integrates factors at multiple levels, including social determinants of health, to identify their role in health, health improvement, and health inequities. NINR promotes research that improves the health of individuals, families, and populations in a variety of settings, translating science in order to maximize the impact of findings on practice and policy.

Advancing health equity is an area of high priority. National Center for Complementary and Integrative Health ( NCCIH ) Office of Research Infrastructure Programs ( ORIP ) ORIP’s mission is to support research infrastructure and related programs, including research resources centers that provide animal models used to study the causes, treatment, and prevention of diseases.

These resources benefit researchers supported by many NIH Institutes, Centers, and Offices (ICOs). ORIP also provides specialized biomedical research training for veterinary scientists. See Section VIII.

Other Information for award authorities and regulations. Section II. Award Information Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.

Application Types Allowed The OER Glossary and the How to Apply Application Guide provide details on these application types. Only those application types listed here are allowed for this NOFO. Not Allowed: Only accepting applications that do not propose clinical trials.

Need help determining whether you are doing a clinical trial? Funds Available and Anticipated Number of Awards The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications. Applicants may request up to $375,000 in direct costs, excluding consortium F&A, for the entire project period of up to 3 years.

The scope of the proposed project should determine the project period. The maximum project period is 3 years. NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.

Section III. Eligibility Information Higher Education Institutions Public/State Controlled Institutions of Higher Education Private Institutions of Higher Education Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.

In addition, all organizations must meet the following criteria at the time of submission: The applicant organization must be an accredited public or non-profit private school that grants baccalaureate or advanced degrees in health professions (see section below for more details) or biomedical and behavioral sciences.

The application must be submitted by the eligible organization with a unique entity identifier (UEI) and a unique NIH eRA Institutional Profile File (IPF) number. At the time of application submission, all components of the institution combined must not have received support from the NIH totaling more than $6 million per year (in both direct and F&A/indirect costs) in 4 of the last 7 years.

A year is defined as a federal fiscal year: from October 1 through September 30. For institutions composed of multiple schools and colleges, the $6 million funding limit is based on the amount of NIH funding received by all of the schools and colleges within the institution as a whole. Note that all activity codes are included in this calculation except the following: C06, S10, and all activity codes starting with a G.

For this NOFO: Only eligible Health Professional or Graduate Institutions may apply For this NOFO: Non-health professional or non-graduate academic institutions are not eligible to apply For the purposes of this NOFO, a graduate school offers advanced degrees, beyond the undergraduate level, in an academic discipline including M. A. , M.

S. , and Ph. D.

degrees. Health professional schools and colleges are accredited institutions that provide education and training leading to a health professional degree, including but not limited to: BSN, MSN, DNP, MD, DDS, DMD, DO, PharmD, DVM, OD, DPT, DC, ND, DPM, MOT, OTD, MS-SLP, CScD, SLPD, AuD, MSPO, MSAT, and MPH.

Eligible health professional schools/colleges may include schools or colleges of nursing, medicine, dentistry, osteopathy, pharmacy, veterinary medicine, public health, optometry, allied health, chiropractic, naturopathy, podiatry, rehabilitation medicine, physical therapy, orthotics & prosthetics, kinesiology, occupational therapy and psychology.

Accreditation must be provided by a body approved for such purpose by the Secretary of Education. For institutions with multiple campuses, eligibility can be considered for each individual campus (e.g., main, satellite, etc.) only if a unique entity identifier (UEI) and NIH IPF number are established for each campus.

For institutions that use one UEI or NIH IPF number for all campuses, eligibility is determined for all campuses (e.g., main, satellite, etc.) together. Additional Eligibility Guidance A signed letter is required from the Provost or similar official with institution-wide responsibility verifying the eligibility of the applicant institution at the time of application submission according to the eligibility criteria indicated above.

See the application instructions for "Other Attachments" on the SF424(R&R) Other Project Information form in Section IV. 2 Instructions for Application Submission. Final eligibility will be validated by NIH prior to award.

To assist in determining eligibility, organizations are encouraged to use the NIH RePORT website under NIH Awards by Location & Organization (http://projectreporter. nih. gov/reporter.

cfm). A REAP grant is permitted to have a subcontract to a non-REAP-eligible institution. However, applicants should keep the goals of the REAP program in mind when preparing the application, which include strengthening the research environment of eligible institutions and engaging students from eligible institutions in research.

It is expected that the majority of the research must be directed by the PD(s)/PI(s) at the recipient institution.

Undergraduate-focused institutions with undergraduate enrollment greater than graduate enrollment should apply to PAR-25-134 , Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15-Clinical Trial Not Allowed) or to PAR-25-148 , Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15- Clinical Trial Required).

Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement , are allowed. Applicant organizations must complete and maintain the following registrations as described in the How to Apply- Application Guide to be eligible to apply for or receive an award.

All registrations must be completed prior to the application being submitted. Registration can take 6 weeks or more, so applicants should begin the registration process as soon as possible. Failure to complete registrations in advance of a due date is not a valid reason for a late submission, please reference the NIH Grants Policy Statement Section 2.

3. 9. 2 Electronically Submitted Applications for additional information.

System for Award Management (SAM) – Applicants must complete and maintain an active registration, which requires renewal at least annually . The renewal process may require as much time as the initial registration. SAM registration includes the assignment of a Commercial and Government Entity (CAGE) Code for domestic organizations which have not already been assigned a CAGE Code.

NATO Commercial and Government Entity (NCAGE) Code – Foreign organizations must obtain an NCAGE code (in lieu of a CAGE code) in order to register in SAM. Unique Entity Identifier (UEI) - A UEI is issued as part of the SAM. gov registration process.

The same UEI must be used for all registrations, as well as on the grant application. eRA Commons - Once the unique organization identifier is established, organizations can register with eRA Commons in tandem with completing their Grants. gov registrations; all registrations must be in place by time of submission.

eRA Commons requires organizations to identify at least one Signing Official (SO) and at least one Program Director/Principal Investigator (PD/PI) account in order to submit an application. Grants. gov – Applicants must have an active SAM registration in order to complete the Grants.

gov registration. Program Directors/Principal Investigators (PD(s)/PI(s)) All PD(s)/PI(s) must have an eRA Commons account. PD(s)/PI(s) should work with their organizational officials to either create a new account or to affiliate their existing account with the applicant organization in eRA Commons.

If the PD/PI is also the organizational Signing Official, they must have two distinct eRA Commons accounts, one for each role. Obtaining an eRA Commons account can take up to 2 weeks.

Eligible Individuals (Program Director/Principal Investigator) Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) is invited to work with their organization to develop an application for support.

For institutions/organizations proposing multiple PDs/PIs, visit the Multiple Program Director/Principal Investigator Policy and submission details in the Senior/Key Person Profile (Expanded) Component of the How to Apply-Application Guide.

To be eligible for a REAP grant, the PD(s)/PI(s) must meet the following additional criteria: Each PD(s)/PI(s) must have a primary appointment at a health professional or graduate school or college within the applicant institution, as defined in " Eligible Institutions ," above. If proposing multiple PD(s)/PI(s), each PD/PI must be at a REAP-eligible institution.

Each PD(s)/PI(s) may not be the PD(s)/PI(s) of an active NIH research grant, including another R15 grant, at the time of award of a REAP grant, although they may be one of the Key Personnel for an active NIH grant held by another PD/PI. Each PD(s)/PI(s) may not be awarded more than one R15 grant at a time, although they may hold successive New or Renewal grants.

This NOFO does not require cost sharing as defined in the NIH Grants Policy Statement Section 1. 2 Definition of Terms . 3.

Additional Information on Eligibility Applicant organizations may submit more than one application, provided that each application is scientifically distinct. The NIH will not accept duplicate or highly overlapping applications under review at the same time, per NIH Grants Policy Statement Section 2. 3.

7. 4 Submission of Resubmission Application . This means that the NIH will not accept: A new (A0) application that is submitted before issuance of the summary statement from the review of an overlapping new (A0) or resubmission (A1) application.

A resubmission (A1) application that is submitted before issuance of the summary statement from the review of the previous new (A0) application. An application that has substantial overlap with another application pending appeal of initial peer review (see NIH Grants Policy Statement 2. 3.

9. 4 Similar, Essentially Identical, or Identical Applications ). Section IV.

Application and Submission Information 1. Requesting an Application Package The application forms package specific to this opportunity must be accessed through ASSIST, Grants. gov Workspace or an institutional system-to-system solution.

Links to apply using ASSIST or Grants. gov Workspace are available in Part 1 of this NOFO. See your administrative office for instructions if you plan to use an institutional system-to-system solution.

2. Content and Form of Application Submission It is critical that applicants follow the instructions in the Research (R) Instructions in the How to Apply - Application Guide except where instructed in this notice of funding opportunity to do otherwise. Conformance to the requirements in the Application Guide is required and strictly enforced.

Applications that are out of compliance with these instructions may be delayed or not accepted for review. All page limitations described in the How to Apply- Application Guide and the Table of Page Limits must be followed. Instructions for Application Submission The following section supplements the instructions found in the How to Apply- Application Guide and should be used for preparing an application to this NOFO.

All instructions in the How to Apply - Application Guide must be followed. SF424(R&R) Project/Performance Site Locations All instructions in the How to Apply- Application Guide must be followed. SF424(R&R) Other Project Information All instructions in the How to Apply- Application Guide must be followed.

Facilities & Other Resources : The following information should be included. A profile of the students of the applicant institution and any information or estimate of the number who have obtained a health professional, baccalaureate or advanced degree and gone on to obtain an academic or professional doctoral or other advanced degree in the health-related sciences during the last five years.

Please note that the race, ethnicity, or sex of students of the applicant institution will not be considered in the application review process or when making funding decisions. Description of plans to inform undergraduate students of potential opportunities to participate in the research project.

Description of the special characteristics of the applicant institution that make it appropriate for a REAP grant awarded through this NOFO, where the goals of this NOFO are to: (1) provide support for meritorious research at health professional or graduate institution or institutional components; (2) strengthen the research environment at these institutions/components; and (3) give health professional, undergraduate and/or graduate students an opportunity to gain significant biomedical research experience through active involvement in the research.

Description of the likely impact of a REAP grant on the PD(s)/PI(s). Description of the likely impact of a REAP grant on the research environment of the applicant institution. Description of the likely impact of the REAP grant on the ability of health professional, undergraduate and/or graduate students at the institution to gain experience conducting biomedical research.

Provide a description of the resources of the recipient institution available for the proposed research (e.g., equipment, supplies, laboratory space, release time, matching funds, etc.). Although the majority of the research must be directed by the PD(s)/PI(s) and conducted at